ID A0A165JCC3_9BASI Unreviewed; 938 AA.
AC A0A165JCC3;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE SubName: Full=DNA mismatch repair protein {ECO:0000313|EMBL:KZT61654.1};
GN ORFNames=CALCODRAFT_479692 {ECO:0000313|EMBL:KZT61654.1};
OS Calocera cornea HHB12733.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Dacrymycetes;
OC Dacrymycetales; Dacrymycetaceae; Calocera.
OX NCBI_TaxID=1353952 {ECO:0000313|EMBL:KZT61654.1, ECO:0000313|Proteomes:UP000076842};
RN [1] {ECO:0000313|EMBL:KZT61654.1, ECO:0000313|Proteomes:UP000076842}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HHB12733 {ECO:0000313|EMBL:KZT61654.1,
RC ECO:0000313|Proteomes:UP000076842};
RX PubMed=26659563; DOI=10.1093/molbev/msv337;
RA Nagy L.G., Riley R., Tritt A., Adam C., Daum C., Floudas D., Sun H.,
RA Yadav J.S., Pangilinan J., Larsson K.H., Matsuura K., Barry K., Labutti K.,
RA Kuo R., Ohm R.A., Bhattacharya S.S., Shirouzu T., Yoshinaga Y.,
RA Martin F.M., Grigoriev I.V., Hibbett D.S.;
RT "Comparative Genomics of Early-Diverging Mushroom-Forming Fungi Provides
RT Insights into the Origins of Lignocellulose Decay Capabilities.";
RL Mol. Biol. Evol. 33:959-970(2016).
CC -!- FUNCTION: Component of the post-replicative DNA mismatch repair system
CC (MMR). {ECO:0000256|RuleBase:RU003756}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the DNA mismatch repair MutS family.
CC {ECO:0000256|ARBA:ARBA00006271, ECO:0000256|RuleBase:RU003756}.
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DR EMBL; KV423921; KZT61654.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A165JCC3; -.
DR STRING; 1353952.A0A165JCC3; -.
DR InParanoid; A0A165JCC3; -.
DR OrthoDB; 168255at2759; -.
DR Proteomes; UP000076842; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR CDD; cd03285; ABC_MSH2_euk; 1.
DR Gene3D; 1.10.1420.10; -; 2.
DR Gene3D; 3.40.1170.10; DNA repair protein MutS, domain I; 1.
DR Gene3D; 3.30.420.110; MutS, connector domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR011184; DNA_mismatch_repair_Msh2.
DR InterPro; IPR007695; DNA_mismatch_repair_MutS-lik_N.
DR InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR InterPro; IPR007861; DNA_mismatch_repair_MutS_clamp.
DR InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR InterPro; IPR016151; DNA_mismatch_repair_MutS_N.
DR InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR InterPro; IPR007860; DNA_mmatch_repair_MutS_con_dom.
DR InterPro; IPR032642; Msh2_ATP-bd.
DR InterPro; IPR036678; MutS_con_dom_sf.
DR InterPro; IPR045076; MutS_family.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11361:SF35; DNA MISMATCH REPAIR PROTEIN MSH2; 1.
DR PANTHER; PTHR11361; DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER; 1.
DR Pfam; PF01624; MutS_I; 1.
DR Pfam; PF05188; MutS_II; 1.
DR Pfam; PF05192; MutS_III; 1.
DR Pfam; PF05190; MutS_IV; 1.
DR Pfam; PF00488; MutS_V; 1.
DR PIRSF; PIRSF005813; MSH2; 1.
DR SMART; SM00534; MUTSac; 1.
DR SMART; SM00533; MUTSd; 1.
DR SUPFAM; SSF53150; DNA repair protein MutS, domain II; 1.
DR SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00486; DNA_MISMATCH_REPAIR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763, ECO:0000256|RuleBase:RU003756};
KW DNA repair {ECO:0000256|RuleBase:RU003756};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU003756};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU003756}; Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000076842}.
FT DOMAIN 742..758
FT /note="DNA mismatch repair proteins mutS family"
FT /evidence="ECO:0000259|PROSITE:PS00486"
SQ SEQUENCE 938 AA; 105070 MW; 61060A6F21BAB59C CRC64;
MMYDKEKPEM ELDNASEVGF CQFFERLPKV AEGTVRLFDR TDYYSVHGED AKYVAQHVYH
TNTVIKYLGK KNGGLPSVTL SMTLAKAFLR EALTAKQLRV EIWQSEGAKK NANFKLGKEA
SPGNLQSVED LLFSDRDLLS APIVMAIKLS TQENIKIVGV AYADASIREI GVSQFPDNDL
FSNIESLVIQ LGVKECLIQS DEKRTDFDLT KLKGVLDRCN VVITERRTNE FAVRNVEQDL
RRILKEETAT VQLPEFDLKT AMAATSALLS YLSILMDESN YGQYTLKHHD LSQYMRLDSS
ALRALNLMPG PQDGAANKNA SVFGLLNRCK TSQGTRLLGA WLKQPLVNLH EIRRRQDLVE
AMVEDSNTRR ALQDDFVKSM PDMRRISKRF QKGIANLEDV VRVYQAIVKL PGLIAALEDI
DTGNDDHKEL VADQWVKNLK EYLTSLEKMA EMVEHTLDLE ELDNHNYVIK PDFDDELKRI
SEDLRNVRDR LDAEHHRVGN ELDLDLDKKL HLESNTVYGY CLRLSKNDAK VIHNVRGYIE
LSTQKAGVYF TTKQLKEASI DHADLTDKYG RMQSGLVKEV VNIAATYTPV LETLDNLVAH
LDVILSFAHV SVNAPIPYIK PTMSEKGTGN IVIKEARHPC LEVQDDVNFI PNDHEMIKGE
SDFQIITGPN MGGKSTYIRQ IGVIALMAQT GCFVPCAEAE LPIFDSILAR VGAGDSQLKG
VSTFMAEMLE TATILKSASK DSLIIIDELG RGTSTYDGFG LAWAISENIA TEINAFCLFA
THFHELTALA QEVSHVKNLH VVAHVTKRGS SNHDRDITLL YKVEPGVCDQ SFGIHVAELA
NFPESVVKLA KRKADELEDF SGVSEPPSKI SQEETDAGTH LIKEFYAALK ERSTADGEDI
AMDERSPDEQ MAILRATVEQ FKSRFEANEW TKDIIAAL
//
