ID A0A165MHA8_9AGAM Unreviewed; 776 AA.
AC A0A165MHA8;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=DNA ligase/mRNA capping enzyme {ECO:0000313|EMBL:KZT18333.1};
GN ORFNames=NEOLEDRAFT_1184374 {ECO:0000313|EMBL:KZT18333.1};
OS Neolentinus lepideus HHB14362 ss-1.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Gloeophyllales; Gloeophyllaceae; Neolentinus.
OX NCBI_TaxID=1314782 {ECO:0000313|EMBL:KZT18333.1, ECO:0000313|Proteomes:UP000076761};
RN [1] {ECO:0000313|EMBL:KZT18333.1, ECO:0000313|Proteomes:UP000076761}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HHB14362 ss-1 {ECO:0000313|EMBL:KZT18333.1,
RC ECO:0000313|Proteomes:UP000076761};
RX PubMed=26659563; DOI=10.1093/molbev/msv337;
RA Nagy L.G., Riley R., Tritt A., Adam C., Daum C., Floudas D., Sun H.,
RA Yadav J.S., Pangilinan J., Larsson K.H., Matsuura K., Barry K., Labutti K.,
RA Kuo R., Ohm R.A., Bhattacharya S.S., Shirouzu T., Yoshinaga Y.,
RA Martin F.M., Grigoriev I.V., Hibbett D.S.;
RT "Comparative Genomics of Early-Diverging Mushroom-Forming Fungi Provides
RT Insights into the Origins of Lignocellulose Decay Capabilities.";
RL Mol. Biol. Evol. 33:959-970(2016).
CC -!- SIMILARITY: Belongs to the ATP-dependent DNA ligase family.
CC {ECO:0000256|ARBA:ARBA00007572}.
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DR EMBL; KV425689; KZT18333.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A165MHA8; -.
DR STRING; 1314782.A0A165MHA8; -.
DR InParanoid; A0A165MHA8; -.
DR OrthoDB; 2788069at2759; -.
DR Proteomes; UP000076761; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003910; F:DNA ligase (ATP) activity; IEA:InterPro.
DR GO; GO:0051103; P:DNA ligation involved in DNA repair; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR Gene3D; 1.10.3260.10; DNA ligase, ATP-dependent, N-terminal domain; 1.
DR Gene3D; 3.30.470.30; DNA ligase/mRNA capping enzyme; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR InterPro; IPR012310; DNA_ligase_ATP-dep_cent.
DR InterPro; IPR016059; DNA_ligase_ATP-dep_CS.
DR InterPro; IPR012308; DNA_ligase_ATP-dep_N.
DR InterPro; IPR036599; DNA_ligase_N_sf.
DR InterPro; IPR029710; LIG4.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR PANTHER; PTHR45997:SF2; ATP DEPENDENT DNA LIGASE DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G02430); 1.
DR PANTHER; PTHR45997; DNA LIGASE 4; 1.
DR Pfam; PF01068; DNA_ligase_A_M; 1.
DR Pfam; PF04675; DNA_ligase_A_N; 1.
DR SUPFAM; SSF56091; DNA ligase/mRNA capping enzyme, catalytic domain; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR PROSITE; PS00697; DNA_LIGASE_A1; 1.
DR PROSITE; PS50160; DNA_LIGASE_A3; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:KZT18333.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000076761}.
FT DOMAIN 421..571
FT /note="ATP-dependent DNA ligase family profile"
FT /evidence="ECO:0000259|PROSITE:PS50160"
FT REGION 743..776
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 743..760
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 776 AA; 87241 MW; 3136B4F2E6ED3820 CRC64;
MASFDLSLSS FTSLLENISH VAPRRTRSYS RGTHPQPVVE IFRHWVAQLK AGHGHVPAGA
TSVVFRLLFP EEDVCRKYEL QETKLAQYLV KIFASAPTSA KQRLIHWNSE SSKGCLGIVV
KDTQDEDAVP QPTLKDLDAL LSELASTSAY SARSNRSNQP KSRRRPRFEI LSSIYSRLTP
SAASFITQII LKDLRPVLYT ITETHFTAAL KEYKSNAVTM LTKDDAMKIW DPSGVMWRAY
KSTNSFEDAS MALESSLPPD LCKLQVGVPI QIPKCRKAQS CLHALQQFRS TDRVWAETKY
DGERAQIHVQ VLNDGVPKIT IYSKSRRDST LDRIAVHPIV LRVLGFDNLT HSDNSNPTRR
RCHSKIWKNI VLEAEMVAFS EELNKIDEFY HIRDLIEFTA QGVRGSRRFT AMAADNDSQT
SASSPRHLAL VFFDLLLLNS VSLLSTPYAT RRALLESIIL PEPGYAMLAD RFLIGEVWEG
GENGEGEEAR GQLREVFAQA LVRREEGLVL KAEKGWYGGW SPWVKLKKDY IPGHGDAVDL
VLLAARWDKD RGRELRVAPG TYTTFYLGAL KNSAECKINS STKPDFQVLA EASYGLSREQ
LEQLNFMIRS AESFVYGSHS PDQLTYTVSG MGCFPKPEVI LEVPLVVEVF GAGFTKERSS
KYYALRFPRL TKVFRRAERT WADATPLGEY QSIALAAVGK DRPDKDVEDW CKGLWGHEAS
PGVSCPVKRK REVEGWRERL MEADEGRAGK RRKTGDQEKR LALKPLASIT NTKGGD
//
