ID A0A165NAW1_EXIGL Unreviewed; 582 AA.
AC A0A165NAW1;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Cora-domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=EXIGLDRAFT_830641 {ECO:0000313|EMBL:KZW00478.1};
OS Exidia glandulosa HHB12029.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Auriculariales; Exidiaceae; Exidia.
OX NCBI_TaxID=1314781 {ECO:0000313|EMBL:KZW00478.1, ECO:0000313|Proteomes:UP000077266};
RN [1] {ECO:0000313|EMBL:KZW00478.1, ECO:0000313|Proteomes:UP000077266}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HHB12029 {ECO:0000313|EMBL:KZW00478.1,
RC ECO:0000313|Proteomes:UP000077266};
RX PubMed=26659563; DOI=10.1093/molbev/msv337;
RA Nagy L.G., Riley R., Tritt A., Adam C., Daum C., Floudas D., Sun H.,
RA Yadav J.S., Pangilinan J., Larsson K.H., Matsuura K., Barry K., Labutti K.,
RA Kuo R., Ohm R.A., Bhattacharya S.S., Shirouzu T., Yoshinaga Y.,
RA Martin F.M., Grigoriev I.V., Hibbett D.S.;
RT "Comparative Genomics of Early-Diverging Mushroom-Forming Fungi Provides
RT Insights into the Origins of Lignocellulose Decay Capabilities.";
RL Mol. Biol. Evol. 33:959-970(2016).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35)
CC family. {ECO:0000256|ARBA:ARBA00009765}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KV425900; KZW00478.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A165NAW1; -.
DR STRING; 1314781.A0A165NAW1; -.
DR InParanoid; A0A165NAW1; -.
DR OrthoDB; 1382333at2759; -.
DR Proteomes; UP000077266; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0046873; F:metal ion transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0015693; P:magnesium ion transport; IEA:UniProt.
DR Gene3D; 3.30.460.20; CorA soluble domain-like; 1.
DR Gene3D; 1.20.58.340; Magnesium transport protein CorA, transmembrane region; 2.
DR InterPro; IPR045861; CorA_cytoplasmic_dom.
DR InterPro; IPR045863; CorA_TM1_TM2.
DR InterPro; IPR002523; MgTranspt_CorA/ZnTranspt_ZntB.
DR PANTHER; PTHR46494; CORA FAMILY METAL ION TRANSPORTER (EUROFUNG); 1.
DR PANTHER; PTHR46494:SF1; CORA FAMILY METAL ION TRANSPORTER (EUROFUNG); 1.
DR Pfam; PF01544; CorA; 1.
DR SUPFAM; SSF143865; CorA soluble domain-like; 1.
DR SUPFAM; SSF144083; Magnesium transport protein CorA, transmembrane region; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000077266};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 493..515
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 527..547
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..64
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..18
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 44..64
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 582 AA; 65362 MW; C5E335B6C9907403 CRC64;
MGRLSESSGS SSDVDHQGMS PKSPVYGDGP QSTRPFEFPT VSAVMDSEQP SQPSTRQSTL
GPAGTRLRQV ALKVMHMQRS STHFNKAGAG AEPGVDPRRQ TAEELYGHLR QRCDITVIDY
NSVRSSSRTL DNEGLRAYLA GDHRRPPWGR VRWIHCNGVS WDVLSALSLE YRVHPLALED
ILHSHAESRS KSSYFMSHLF LRVMAHQALI GDSDEVSGIT DLARSSSPVE LDDDDSDESR
PALFHFKPRS STFSSRKDVE AAQGQATFDT TKTQRWQHPD EDIERRAERA ELHVIKDDED
RTKLAMNNLF ILLWRDGTVI SIFAKPGSDF AAPIVSRLKS RDTILRATAD PSLLVQSMLD
LVVDQALEVI DRYHAQLTKL EASILIKPQM TAVRSLHILS GDLAMRKRSL EPIKSLVFGL
RRYDLDRSAA LTEDPKEPPV GFMSHKAKIY LADVLDHMDY ILSSIDLFST ISENLISYSF
NMSGYLTNET MRLLTLVTII FMPLTLLTGY FGMNFMPFPA ADNHSDVLFW IIALPVMSII
VPLFLWSDIR RMVHYLRKTS SAKKVSKAIK AGRTWPSRSG TL
//
