ID   A0A165RVG4_9GAMM        Unreviewed;       432 AA.
AC   A0A165RVG4;
DT   06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT   06-JUL-2016, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   SubName: Full=Guanine permease {ECO:0000313|EMBL:KZX54835.1};
GN   ORFNames=A3709_07335 {ECO:0000313|EMBL:KZX54835.1};
OS   Halioglobus sp. HI00S01.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Cellvibrionales; Halieaceae;
OC   Halioglobus.
OX   NCBI_TaxID=1822214 {ECO:0000313|EMBL:KZX54835.1, ECO:0000313|Proteomes:UP000077184};
RN   [1] {ECO:0000313|EMBL:KZX54835.1, ECO:0000313|Proteomes:UP000077184}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HI00S01 {ECO:0000313|EMBL:KZX54835.1,
RC   ECO:0000313|Proteomes:UP000077184};
RA   Sosa O.A.;
RT   "Microbial cycling of marine high molecular weight dissolved organic
RT   matter.";
RL   Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|PIRNR:PIRNR005353};
CC       Multi-pass membrane protein {ECO:0000256|PIRNR:PIRNR005353}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC       2.A.40) family. Azg-like subfamily. {ECO:0000256|ARBA:ARBA00005697,
CC       ECO:0000256|PIRNR:PIRNR005353}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KZX54835.1}.
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DR   EMBL; LWEE01000265; KZX54835.1; -; Genomic_DNA.
DR   RefSeq; WP_066057551.1; NZ_LWEE01000265.1.
DR   OrthoDB; 9808458at2; -.
DR   Proteomes; UP000077184; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:1904823; P:purine nucleobase transmembrane transport; IEA:UniProt.
DR   InterPro; IPR045018; Azg-like.
DR   InterPro; IPR026033; Azg-like_bact_archaea.
DR   InterPro; IPR006043; NCS2.
DR   PANTHER; PTHR43337; XANTHINE/URACIL PERMEASE C887.17-RELATED; 1.
DR   PANTHER; PTHR43337:SF1; XANTHINE_URACIL PERMEASE C887.17-RELATED; 1.
DR   Pfam; PF00860; Xan_ur_permease; 1.
DR   PIRSF; PIRSF005353; PbuG; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW   ECO:0000256|PIRNR:PIRNR005353};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR005353};
KW   Reference proteome {ECO:0000313|Proteomes:UP000077184};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|PIRNR:PIRNR005353};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|PIRNR:PIRNR005353};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR005353}.
FT   TRANSMEM        20..39
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        51..72
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        98..122
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        134..158
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        170..190
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        197..215
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        235..256
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        321..340
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        378..402
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        414..431
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   432 AA;  45104 MW;  9D597CECE18C12C2 CRC64;
     MQALLERLFK LEHHQTRVST ELVAGLTTFI TMAYIIFVNP QMMASAGMDH GASFAATCLA
     AALACIFMGL YANWPVGLAP GMGLNAFFTY TVVGEMGYSW QVALGAVFIA GILFVIMSVT
     PLRAWMLNSI PKDLRVAMAA GVGLFIGFIG LKSAGLIIDN PATLISLGDL TQPEPLLGAL
     GFLLIAGLSV RQVPGSIMLG VLLITVIGLV AGLVEYQGIV SPPPSIAPTF MQLDIAGALE
     VGMVSVVIAI LFVNLFDTAG TLLGVATRAH LVNEEGEIQN MNKALQADSS SSVVGALFGC
     APVTSYVESA AGVAAGGRTG LTAVVVGLLF LLAMFFAPLA GMXPAYATAG ALVYVALLMM
     SGMEQLDYSD ATELTPALLT IIMIPLSFSI ANGIAVGFIS YTVIKVFAGR ANDVSFGAWF
     LTTIFVAKFA FF
//