ID A0A165U8V5_9AGAM Unreviewed; 663 AA.
AC A0A165U8V5;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=RA-domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=NEOLEDRAFT_1239967 {ECO:0000313|EMBL:KZT27806.1};
OS Neolentinus lepideus HHB14362 ss-1.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Gloeophyllales; Gloeophyllaceae; Neolentinus.
OX NCBI_TaxID=1314782 {ECO:0000313|EMBL:KZT27806.1, ECO:0000313|Proteomes:UP000076761};
RN [1] {ECO:0000313|EMBL:KZT27806.1, ECO:0000313|Proteomes:UP000076761}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HHB14362 ss-1 {ECO:0000313|EMBL:KZT27806.1,
RC ECO:0000313|Proteomes:UP000076761};
RX PubMed=26659563; DOI=10.1093/molbev/msv337;
RA Nagy L.G., Riley R., Tritt A., Adam C., Daum C., Floudas D., Sun H.,
RA Yadav J.S., Pangilinan J., Larsson K.H., Matsuura K., Barry K., Labutti K.,
RA Kuo R., Ohm R.A., Bhattacharya S.S., Shirouzu T., Yoshinaga Y.,
RA Martin F.M., Grigoriev I.V., Hibbett D.S.;
RT "Comparative Genomics of Early-Diverging Mushroom-Forming Fungi Provides
RT Insights into the Origins of Lignocellulose Decay Capabilities.";
RL Mol. Biol. Evol. 33:959-970(2016).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004413};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004413};
CC Cytoplasmic side {ECO:0000256|ARBA:ARBA00004413}. Cytoplasm,
CC cytoskeleton, actin patch {ECO:0000256|ARBA:ARBA00004134}. Endosome
CC membrane {ECO:0000256|ARBA:ARBA00004125}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004125}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004125}. Membrane
CC {ECO:0000256|ARBA:ARBA00004287}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004287}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004287}.
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DR EMBL; KV425560; KZT27806.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A165U8V5; -.
DR STRING; 1314782.A0A165U8V5; -.
DR InParanoid; A0A165U8V5; -.
DR OrthoDB; 1423392at2759; -.
DR Proteomes; UP000076761; Unassembled WGS sequence.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd01786; RA_STE50; 1.
DR CDD; cd00174; SH3; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 2.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR InterPro; IPR000159; RA_dom.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR15735; FCH AND DOUBLE SH3 DOMAINS PROTEIN; 1.
DR PANTHER; PTHR15735:SF20; PROTEIN NERVOUS WRECK; 1.
DR Pfam; PF00788; RA; 1.
DR Pfam; PF07647; SAM_2; 1.
DR Pfam; PF00018; SH3_1; 2.
DR SMART; SM00314; RA; 1.
DR SMART; SM00454; SAM; 1.
DR SMART; SM00326; SH3; 2.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR SUPFAM; SSF50044; SH3-domain; 2.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS50200; RA; 1.
DR PROSITE; PS50105; SAM_DOMAIN; 1.
DR PROSITE; PS50002; SH3; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000076761};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 16..73
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT DOMAIN 237..314
FT /note="Ras-associating"
FT /evidence="ECO:0000259|PROSITE:PS50200"
FT DOMAIN 441..510
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 548..608
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 159..234
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 321..428
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 639..663
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 104..131
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 164..212
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 327..365
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 401..428
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 639..654
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 663 AA; 72682 MW; 20D4E3635CE13750 CRC64;
MYAGMNEEPQ KNILDWDEND VQAFFAKLGY PQYEVQIREH NISGDVLCML DADTLKEVGV
ATVGQRLAIL KAVYLEKLVH DVPIEDDQYV PPSEAEERNS NVSVDKLYTL VRSQEERLHH
LEDENHRLRD SLHSCMEDLS GIRSSYARPS EDSLLRRQPS FKWAHYKPNQ SPTKASLESP
QPSPQRMEHD TSYNARNGSQ SQQTNDKWKG SPADNSSGAM VPVPPKPVRQ ESSDNLKSFK
VSLDDPAWKV LPAALKKYKI NNDDWQNYAM FICYGSSGNR IERCLSFDEK PLLLFQKLKD
AKKNPVFMLK HIKDIRSPIA VAQQKQAARK ASESSTSGSG PKTAGGSAGQ GRSTSRPSKL
QVHDPIATSS PPLLTGMTSA QGGWPEIMSP AAETKERSEE VGLTSSTTTT VSGTEPLKTK
AQENNEPNGI ISTRENMVAS AGMSYAVAIY PYMAEQEDEF DVVVGDTFII LSRARGWWVV
QRDPAGTGAV EPDMTKQGWV PAGCLLETNI PVASAVAEAN ALRGPMSDSS PSSPQSKKTP
ILPLSIVSTS FPGIALMDYE GKGDEELDLM KDDALRVFKR YNHWSYAVKE EGGDRGWVPS
WYIGKISATG ATPATPSTSH PPAIISSSMT LDAMADSNTA SQQLQVSPMS SAFPPVAKTT
PLL
//
