ID A0A165UAV1_9APHY Unreviewed; 1143 AA.
AC A0A165UAV1;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Ras GEF {ECO:0000313|EMBL:KZT74642.1};
GN ORFNames=DAEQUDRAFT_700547 {ECO:0000313|EMBL:KZT74642.1};
OS Daedalea quercina L-15889.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Polyporales; Daedalea.
OX NCBI_TaxID=1314783 {ECO:0000313|EMBL:KZT74642.1, ECO:0000313|Proteomes:UP000076727};
RN [1] {ECO:0000313|EMBL:KZT74642.1, ECO:0000313|Proteomes:UP000076727}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=L-15889 {ECO:0000313|EMBL:KZT74642.1,
RC ECO:0000313|Proteomes:UP000076727};
RX PubMed=26659563; DOI=10.1093/molbev/msv337;
RA Nagy L.G., Riley R., Tritt A., Adam C., Daum C., Floudas D., Sun H.,
RA Yadav J.S., Pangilinan J., Larsson K.H., Matsuura K., Barry K., Labutti K.,
RA Kuo R., Ohm R.A., Bhattacharya S.S., Shirouzu T., Yoshinaga Y.,
RA Martin F.M., Grigoriev I.V., Hibbett D.S.;
RT "Comparative Genomics of Early-Diverging Mushroom-Forming Fungi Provides
RT Insights into the Origins of Lignocellulose Decay Capabilities.";
RL Mol. Biol. Evol. 33:959-970(2016).
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DR EMBL; KV429032; KZT74642.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A165UAV1; -.
DR STRING; 1314783.A0A165UAV1; -.
DR OrthoDB; 4819765at2759; -.
DR Proteomes; UP000076727; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR CDD; cd06224; REM; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.840.10; Ras guanine-nucleotide exchange factors catalytic domain; 1.
DR Gene3D; 1.20.870.10; Son of sevenless (SoS) protein Chain: S domain 1; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR008937; Ras-like_GEF.
DR InterPro; IPR000651; Ras-like_Gua-exchang_fac_N.
DR InterPro; IPR023578; Ras_GEF_dom_sf.
DR InterPro; IPR001895; RASGEF_cat_dom.
DR InterPro; IPR036964; RASGEF_cat_dom_sf.
DR PANTHER; PTHR23113; GUANINE NUCLEOTIDE EXCHANGE FACTOR; 1.
DR PANTHER; PTHR23113:SF99; RAP GUANINE NUCLEOTIDE EXCHANGE FACTOR 1; 1.
DR Pfam; PF00617; RasGEF; 1.
DR Pfam; PF00618; RasGEF_N; 1.
DR SMART; SM00175; RAB; 1.
DR SMART; SM00147; RasGEF; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48366; Ras GEF; 1.
DR PROSITE; PS50009; RASGEF_CAT; 1.
DR PROSITE; PS50212; RASGEF_NTER; 1.
PE 4: Predicted;
KW Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658,
KW ECO:0000256|PROSITE-ProRule:PRU00168};
KW Reference proteome {ECO:0000313|Proteomes:UP000076727}.
FT DOMAIN 636..761
FT /note="N-terminal Ras-GEF"
FT /evidence="ECO:0000259|PROSITE:PS50212"
FT DOMAIN 877..1120
FT /note="Ras-GEF"
FT /evidence="ECO:0000259|PROSITE:PS50009"
FT REGION 1..88
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 102..244
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 512..636
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 792..861
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 22..67
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 102..145
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 166..180
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 181..204
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 223..237
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 512..530
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 545..559
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 571..591
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 593..615
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 620..634
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 812..829
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 838..856
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1143 AA; 126115 MW; 40BDDEF1604573FE CRC64;
MTAKNRQIDL PPIPFLPPIQ MPDASQLSSS SQAANRTNLQ SLRRHIPSPH ASQDTTMTAQ
TSQDAVTPPM ADEDYYGAPS PTFSQSSSLR KSLSVDSFVK ARQQGIPQST RAARGNTLSS
NLAPPPETRQ RVHTQSVSVP VDSAASSSRV PLREREKPAI PPLPTPSRSR GTSVSTNADD
REGTKFFDES DLERSEDLSR RTRKSKTMSR QLMPPPGELG LPSRLQSVNT SPSISASHPP
APIMPVRSSS LSHKLAKQKQ AMSVDTRIPP QHPQITIAVM GSAGCGKSTA IQKGLKVYGL
SDPVVATISP AMNDSDEAPV TCLERTGKLS FTSNSQEYAL RVVEVDTSKL DLNNTGCEDW
EKPSIKGVVV CYDCSREETF KHVVEGIREF ALLKIPLIVL ACKSDLEKRV DPTQATRVLE
EFDAGLVEVS LTTSAGKERI RGAFEWLLRA IYHELQAEIP GSARSERDGY RNPASPSVLG
ALTASEISRA SSATPTAASV GATQLVSSYS QTQPFLSQPM TQTETPPQSQ PPSHMGTPHP
SHALRLPSPS GPTPSRTPTT PTSPSRARST SDLLSEHEKS KREERESHSA GRNVAHGSPN
VRSRGSLNAL TVTSSGEGGH IADDSHDASR DVSVKESRAP PWMVLDELLD KLLFMAVSDD
DPLFVSHFLL TYRRFASPRS VLLAMQKRMR ALEQPTGDPM FACYAQLRIC LLLDRWITTY
PTDFAVPGAA GALRALIKST LTKTYLLHYG ALFLPFLETV PTLRDRDASW ALKVEEDSDG
SSFVSDDADF AVTGSDSRSL PELPTRGPQR NGGQPAPGQT VTARDRKSSL PLSVTAKALG
LGSSTPTSSN AESPPEPSPK QLLKRLQNMS DEVLKADFGQ IAESITRIEA RYFLQIEPRH
WLQHVFTPGK KDPEKDPIAK YNQVSNRLAD WVVSLILCHD KPKKRATQIE KFVQVAEVLR
VQHNYSALRA FVAGINSATF EGDLALEIFQ TRTPDQWKRF QSYDHLLQSV RSHQKYRMAL
RNSKGACIPA LEIHLSDLIR AHEGNPDYQD DDPTKIHWAK FNMMARFIDV ITQCQEGCRT
SEQFRDVEKL RQQEPWYLRW ESDNGLMSLE MQRSRIAPPD ADDDYGQLYQ SKDAAAIRKI
FFW
//
