ID   A0A165XB03_9AGAM        Unreviewed;       702 AA.
AC   A0A165XB03;
DT   06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT   06-JUL-2016, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=RhoGAP-domain-containing protein {ECO:0000313|EMBL:KZV59915.1};
GN   ORFNames=PENSPDRAFT_659856 {ECO:0000313|EMBL:KZV59915.1};
OS   Peniophora sp. CONT.
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Russulales; Peniophoraceae; Peniophora.
OX   NCBI_TaxID=1314672 {ECO:0000313|EMBL:KZV59915.1, ECO:0000313|Proteomes:UP000077086};
RN   [1] {ECO:0000313|EMBL:KZV59915.1, ECO:0000313|Proteomes:UP000077086}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CONT {ECO:0000313|EMBL:KZV59915.1,
RC   ECO:0000313|Proteomes:UP000077086};
RX   PubMed=26659563; DOI=10.1093/molbev/msv337;
RA   Nagy L.G., Riley R., Tritt A., Adam C., Daum C., Floudas D., Sun H.,
RA   Yadav J.S., Pangilinan J., Larsson K.H., Matsuura K., Barry K., Labutti K.,
RA   Kuo R., Ohm R.A., Bhattacharya S.S., Shirouzu T., Yoshinaga Y.,
RA   Martin F.M., Grigoriev I.V., Hibbett D.S.;
RT   "Comparative Genomics of Early-Diverging Mushroom-Forming Fungi Provides
RT   Insights into the Origins of Lignocellulose Decay Capabilities.";
RL   Mol. Biol. Evol. 33:959-970(2016).
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DR   EMBL; KV424929; KZV59915.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A165XB03; -.
DR   STRING; 1314672.A0A165XB03; -.
DR   InParanoid; A0A165XB03; -.
DR   OrthoDB; 5482027at2759; -.
DR   Proteomes; UP000077086; Unassembled WGS sequence.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProt.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR   Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR   InterPro; IPR027267; AH/BAR_dom_sf.
DR   InterPro; IPR031160; F_BAR.
DR   InterPro; IPR001060; FCH_dom.
DR   InterPro; IPR008936; Rho_GTPase_activation_prot.
DR   InterPro; IPR000198; RhoGAP_dom.
DR   PANTHER; PTHR23176:SF134; ACTIVATING PROTEIN, PUTATIVE-RELATED; 1.
DR   PANTHER; PTHR23176; RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN; 1.
DR   Pfam; PF00611; FCH; 1.
DR   Pfam; PF00620; RhoGAP; 1.
DR   SMART; SM00324; RhoGAP; 1.
DR   SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR   SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR   PROSITE; PS51741; F_BAR; 1.
DR   PROSITE; PS50238; RHOGAP; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|PROSITE-ProRule:PRU01077};
KW   Reference proteome {ECO:0000313|Proteomes:UP000077086}.
FT   DOMAIN          110..399
FT                   /note="F-BAR"
FT                   /evidence="ECO:0000259|PROSITE:PS51741"
FT   DOMAIN          494..688
FT                   /note="Rho-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50238"
FT   REGION          1..86
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          221..251
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          430..490
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        31..52
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        446..489
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   702 AA;  75728 MW;  0C319722159FD65E CRC64;
     MSVDGQHPSR APMSLDGHTH PHDDHPSVSS GLPSDAYSRP SLSLSSSTSI SPPPDRDDKR
     SSYTGSLTAK PFTPSVAGGG GGGPSQAALA AGADYISLSE QPEAPPLVDA SFDEDVLRAL
     CTLDCSVPLM TDRLKQDLAA TKEVAGFLKR RAAVEDEYGR KLLKTARSTA ESYALSDGKA
     GSFVNAWSQC LRIHERMGEN RVRYASRLRE MADDLGKLSA ETERARQTHK DAAESAEADL
     RASEQSTEKA KLRLDGSADE LERLLLAKEG ESAKDGVQIR PPGAGGTGKR ALGKATALLK
     GRGPAAIQRQ EEDVRTRLNA NGVSYNKSME DTQKRRQEYF GFHLPRTLRA LKEASDEIDL
     GTQYHLQRYA FLTESIVMAD GQILAPTTNT IGKDGKEEDN TGLQAALAAL DYRADFRVYM
     QNYAYAHGGT AKGPRRTGPE HEGFLPPLPQ HVPSPRTALP TNGFPPPPTS ASSTTTPLPP
     PPPLQIPPRA TFGIPLSSQL LRDNAEIPPI LIKLTSFIEK YGLLSQGIYR LSGTMSKINK
     LKGLLDEGLD KVDLDREEWK GDVNNVASAA KAWFRELPEG VMTDALRLGF LDAAAIENDR
     LRHIRLHERI NDLPDANYAT LKFFLGHLSR IAQHADANQM SVGNLAIVFG PTLFGSPAGA
     GQGSGGGGEL VLQNKAIETI LEHYADIFID EGEAEQPGPA VP
//