ID A0A165Y4J9_9AGAM Unreviewed; 889 AA.
AC A0A165Y4J9;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=SPX-domain-containing protein {ECO:0000313|EMBL:KZV60914.1};
GN ORFNames=PENSPDRAFT_659281 {ECO:0000313|EMBL:KZV60914.1};
OS Peniophora sp. CONT.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Russulales; Peniophoraceae; Peniophora.
OX NCBI_TaxID=1314672 {ECO:0000313|EMBL:KZV60914.1, ECO:0000313|Proteomes:UP000077086};
RN [1] {ECO:0000313|EMBL:KZV60914.1, ECO:0000313|Proteomes:UP000077086}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CONT {ECO:0000313|EMBL:KZV60914.1,
RC ECO:0000313|Proteomes:UP000077086};
RX PubMed=26659563; DOI=10.1093/molbev/msv337;
RA Nagy L.G., Riley R., Tritt A., Adam C., Daum C., Floudas D., Sun H.,
RA Yadav J.S., Pangilinan J., Larsson K.H., Matsuura K., Barry K., Labutti K.,
RA Kuo R., Ohm R.A., Bhattacharya S.S., Shirouzu T., Yoshinaga Y.,
RA Martin F.M., Grigoriev I.V., Hibbett D.S.;
RT "Comparative Genomics of Early-Diverging Mushroom-Forming Fungi Provides
RT Insights into the Origins of Lignocellulose Decay Capabilities.";
RL Mol. Biol. Evol. 33:959-970(2016).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Vacuole membrane
CC {ECO:0000256|ARBA:ARBA00004128}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004128}.
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DR EMBL; KV424814; KZV60914.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A165Y4J9; -.
DR STRING; 1314672.A0A165Y4J9; -.
DR InParanoid; A0A165Y4J9; -.
DR OrthoDB; 11387at2759; -.
DR Proteomes; UP000077086; Unassembled WGS sequence.
DR GO; GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
DR CDD; cd07751; PolyPPase_VTC4_like; 1.
DR CDD; cd14480; SPX_VTC2_like; 1.
DR Gene3D; 3.20.100.30; VTC, catalytic tunnel domain; 1.
DR InterPro; IPR003807; DUF202.
DR InterPro; IPR004331; SPX_dom.
DR InterPro; IPR018966; VTC_domain.
DR InterPro; IPR042267; VTC_sf.
DR PANTHER; PTHR46140; VACUOLAR TRANSPORTER CHAPERONE 1-RELATED; 1.
DR PANTHER; PTHR46140:SF1; VACUOLAR TRANSPORTER CHAPERONE 4; 1.
DR Pfam; PF02656; DUF202; 1.
DR Pfam; PF03105; SPX; 2.
DR Pfam; PF09359; VTC; 1.
DR PROSITE; PS51382; SPX; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000077086};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Vacuole {ECO:0000256|ARBA:ARBA00022554}.
FT TRANSMEM 792..812
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 818..841
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 862..881
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..193
FT /note="SPX"
FT /evidence="ECO:0000259|PROSITE:PS51382"
FT REGION 87..139
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 540..590
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 621..682
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 707..751
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 87..112
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 113..130
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 667..682
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 707..726
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 737..751
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 889 AA; 100665 MW; FC76809A3ADEFB28 CRC64;
MKFGRKINQD LYSEWRPFYI DYTKLKRELK TRTTSHNWDD EDEEAFIRLL ELELDKVNDF
QSSKTAELST RIRNTEKAVK RLVAEEQAHL RHGHSQDTSG DPEEQLVDDR GPDGGSDDED
ESDDEDHVAL SSEDDTSVDR DEQFVALEEE VAELVADVHD LALFSKLNFT GFMKILKKHD
KKTGRKLKST FSQRYLERRP FHKYNWDALI IKLSRSYDLV RTRGHPVAGD SSAGGSQSAF
VRQTTKYWVH PDNLVPLKLA ILRHLPVLVF DANKEFEEKD AAITSIYFDN EDLELYLGRL
EKTEGAQAVR LRWYGDVNNR QIFVERKTHR EDWTGEKSVK ARFPIAEDKV NAFLSGEYDM
EPEFRALVTK GKKTVQEVEN MIQLANEVQY AIITKQLQPV MRTFYNRTAF QLPGDARVRI
SLDTELTMVR EDNWDGRQRA GENWRRTDIG IDHPFDQLAP EDKELFPYGV LEVKLQTQFG
QEPPRWVLEL VNSHLVEAVP KFSKFIHGCA TLLPHRVDLI PFWLPQMDVD ILKPDTGLMR
LDRPKHDSSA RSSRLNSGAH TPASGSDART PDEPGYTEPL SEDEDDGEEA VLRPARDEGA
VARLSTVDAA EATAFREKLL AASSSRSGSL RGSRKDKNQN QRVRLTIPEG RVQSDDAPEE
EHHNGNGNGA APSTSPQPEN GTLSRRALAI NPLAPASIFD AAFKKRLDGK PNGHTQADHA
REDESDEDET RPNDDSDADE SEAVRALEGA PRTDDERILV RDWRAPAGKR IAIPIRIEPK
VYFATERTFL KWLHFSIYVG TVATTLLNFI PADDARGLVS AAFFTLAALA SIAYSAGVFV
YRARRIRMRA ASGMYYDKWG PTVLCALLLL ALVVNVIFRM TEVASSGED
//
