ID A0A165ZIS7_DAUCS Unreviewed; 1111 AA.
AC A0A165ZIS7;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KZN00079.1};
GN ORFNames=DCAR_008833 {ECO:0000313|EMBL:KZN00079.1};
OS Daucus carota subsp. sativus (Carrot).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Apiales; Apiaceae; Apioideae; Scandiceae; Daucinae;
OC Daucus; Daucus sect. Daucus.
OX NCBI_TaxID=79200 {ECO:0000313|EMBL:KZN00079.1};
RN [1] {ECO:0000313|EMBL:KZN00079.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Leaf {ECO:0000313|EMBL:KZN00079.1};
RX PubMed=27158781; DOI=10.1038/ng.3565;
RA Iorizzo M., Ellison S., Senalik D., Zeng P., Satapoomin P., Huang J.,
RA Bowman M., Iovene M., Sanseverino W., Cavagnaro P., Yildiz M.,
RA Macko-Podgorni A., Moranska E., Grzebelus E., Grzebelus D., Ashrafi H.,
RA Zheng Z., Cheng S., Spooner D., Van Deynze A., Simon P.;
RT "A high-quality carrot genome assembly provides new insights into
RT carotenoid accumulation and asterid genome evolution.";
RL Nat. Genet. 48:657-666(2016).
CC -!- FUNCTION: Confers resistance to late blight (Phytophthora infestans)
CC races carrying the avirulence gene Avr1. Resistance proteins guard the
CC plant against pathogens that contain an appropriate avirulence protein
CC via an indirect interaction with this avirulence protein. That triggers
CC a defense system including the hypersensitive response, which restricts
CC the pathogen growth. {ECO:0000256|ARBA:ARBA00002074}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004170};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004170}.
CC -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC {ECO:0000256|ARBA:ARBA00008894}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KZN00079.1}.
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DR EMBL; LNRQ01000003; KZN00079.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A165ZIS7; -.
DR EnsemblPlants; KZN00079; KZN00079; DCAR_008833.
DR Gramene; KZN00079; KZN00079; DCAR_008833.
DR OMA; PKDYFFE; -.
DR Proteomes; UP000077755; Chromosome 3.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR GO; GO:0051707; P:response to other organism; IEA:UniProt.
DR Gene3D; 1.20.5.4130; -; 1.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR041118; Rx_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR PANTHER; PTHR23155:SF1235; DISEASE RESISTANCE RPP13-LIKE PROTEIN 1; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF18052; Rx_N; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF52047; RNI-like; 1.
DR PROSITE; PS00018; EF_HAND_1; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Hypersensitive response {ECO:0000256|ARBA:ARBA00022667};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW Reference proteome {ECO:0000313|Proteomes:UP000077755}.
FT DOMAIN 11..97
FT /note="Disease resistance N-terminal"
FT /evidence="ECO:0000259|Pfam:PF18052"
FT DOMAIN 133..357
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
SQ SEQUENCE 1111 AA; 125500 MW; 9CBF79DE0D44C625 CRC64;
MVDAFVADLA SGLVVKLVSL AAEELIQAWN LQEDLVTLGE RLETIDALLS DADSKRLNMS
AVQSWFNKLE DVAHVADAFM DELAYEVTRQ KVENRSKARE IRNTPPFEDE SLIVGRDDEI
SFLVKTVCTN HAEDLPVIAV MGMGGQGKTT LARMVYNRDV VTDMFKKRMW VTVSDDFDFM
KILNQMVASL TSTASVLENT EGLIKKLQSF LRDVKFLLVL DDVWNERTEK WNKLRDSLLG
VGGASGSMIL VTTRKQKVVD VMRCFITHRV EKLSEEDSWE LFKRRAFSRG GVIETARFAA
MGREMVERCG GLPLAINALG GLLHSKKSEQ EWLRIQDSAT WDSNDDVLPS LRLSYDNLPH
SSLKKCFAYC SILPKDSRIS KDEMVRIWMA LGFLLPPKGS NKLMEDIGRE YFNILLGNCL
LQNGDIRDYK MHDLVHDLAL DLSRNHSATV KADGHELNDI SKAIYVKVDK GITNIKPPLL
KRNFEKVQVL YADAPIVKDL VPYPSHLIGL VLEGTFEDDP LPSSLSTLKY LKYLDISRCY
MTKNKLPDYI TRLYNLQTLS VRSVTQLPRN ICNLINLRHI LVDAPYYDFE NSDIITVFSR
IERLTCLQTL PFFIVSRDHQ CVIGQLGSLR NLQGTLTLYG LSDVENMEEA RKASLLTKSN
IERLQLDWRK NKDVMEEKEN NHEDVMEGLE PHANLRELIV ENFMGKKFAA WITIMTNLEV
ITFINCNRCE EFPQLGHLPK LRMIDIEGMD NVKVISSHLC GGRQGSISGE LNDDGAEETV
LTMYPSLKNL SLNNMPKLEE WLDPATDTSD EDRNNVLAFS ELVELIIWGC PKLTRIPGSC
YPLMKTLKIK DLDNSKLLES MSEKACGLTG VYLDNISGRV GCSSSSSCSS SSMNCIIGKL
LKNNSVSLET LRVIKLQGLT HLTLGAGLKS LCVSDLPDLN TINIVKGSDA LKYLSISKCL
NYEVFAQSVS CTIERLELGP FSEDLDEFPW PLSFSFPNVI KLTVSGWEKL KWIVDEGQPD
DYLSSIFPAL RQLWIDSFKG VKSLPISLAK LPFLESLYIW NCGNLESLPK FHHNFQYLDI
IGCPIIKERY RRGSGPEWSK IQHIKQIVGL G
//
