ID   A0A166A4S8_EXIGL        Unreviewed;       894 AA.
AC   A0A166A4S8;
DT   06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT   06-JUL-2016, sequence version 1.
DT   24-JAN-2024, entry version 23.
DE   SubName: Full=Glycoside hydrolase {ECO:0000313|EMBL:KZV88459.1};
GN   ORFNames=EXIGLDRAFT_722638 {ECO:0000313|EMBL:KZV88459.1};
OS   Exidia glandulosa HHB12029.
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Auriculariales; Exidiaceae; Exidia.
OX   NCBI_TaxID=1314781 {ECO:0000313|EMBL:KZV88459.1, ECO:0000313|Proteomes:UP000077266};
RN   [1] {ECO:0000313|EMBL:KZV88459.1, ECO:0000313|Proteomes:UP000077266}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HHB12029 {ECO:0000313|EMBL:KZV88459.1,
RC   ECO:0000313|Proteomes:UP000077266};
RX   PubMed=26659563; DOI=10.1093/molbev/msv337;
RA   Nagy L.G., Riley R., Tritt A., Adam C., Daum C., Floudas D., Sun H.,
RA   Yadav J.S., Pangilinan J., Larsson K.H., Matsuura K., Barry K., Labutti K.,
RA   Kuo R., Ohm R.A., Bhattacharya S.S., Shirouzu T., Yoshinaga Y.,
RA   Martin F.M., Grigoriev I.V., Hibbett D.S.;
RT   "Comparative Genomics of Early-Diverging Mushroom-Forming Fungi Provides
RT   Insights into the Origins of Lignocellulose Decay Capabilities.";
RL   Mol. Biol. Evol. 33:959-970(2016).
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 5 (cellulase A) family.
CC       {ECO:0000256|ARBA:ARBA00005641}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; KV426099; KZV88459.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A166A4S8; -.
DR   STRING; 1314781.A0A166A4S8; -.
DR   InParanoid; A0A166A4S8; -.
DR   OrthoDB; 69117at2759; -.
DR   Proteomes; UP000077266; Unassembled WGS sequence.
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR   GO; GO:1901136; P:carbohydrate derivative catabolic process; IEA:UniProt.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProt.
DR   Gene3D; 3.20.20.80; Glycosidases; 2.
DR   Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR   InterPro; IPR041036; GH5_C.
DR   InterPro; IPR001547; Glyco_hydro_5.
DR   InterPro; IPR013780; Glyco_hydro_b.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   PANTHER; PTHR31308; -; 1.
DR   PANTHER; PTHR31308:SF5; ERGOSTERYL-BETA-GLUCOSIDASE; 1.
DR   Pfam; PF00150; Cellulase; 1.
DR   Pfam; PF18564; Glyco_hydro_5_C; 1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:KZV88459.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000077266}.
FT   DOMAIN          86..146
FT                   /note="Glycoside hydrolase family 5"
FT                   /evidence="ECO:0000259|Pfam:PF00150"
FT   DOMAIN          676..732
FT                   /note="Glycoside hydrolase family 5 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF18564"
FT   REGION          741..785
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        751..783
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   894 AA;  99189 MW;  4BB172AD5CE98AD1 CRC64;
     MPRVPTLSPA TGASVPHHYV HTTTGQFVDT SGRTLIFRGV NLSGSSKAPL GEQSQKLEDF
     WENAEAGGNS FSGRPLNVDD GSADVHLARL RGWGFNMLRF PVTWEALEHA GPGQYDFEFM
     DYVIRVLQKC KDYGFRIFMD PHQDVWSRFT GGSGAPLWTI YACGMNPRNF TAGRTHMLHC
     EWPSPDASEP SAYPAMMWST NYGRLGSQTL YTMFFGGRDF APKCIIDGVN IQDYLQDHFI
     TAFGLLADRI RERAPELYDA CIVGWDSLNE PAEGLIGYPD VREPSNEQSA QLKKGPFAYP
     AQSFKLGMGQ PQTVENWDFG GFGPSKKGTV TIDPQGVRAW LDPQDDVKYT ARWGWKRDPG
     WTLGTCVWAL HGVWDIASGE VLVPNYFARE TPFTADYWRP HWKKWIERIR PAHPESIHFV
     QPPVFALPPP LDEADTRGRV CYAPHYYDGL TLVSRHWNWY NADALGVLRG KYSAPWQAVK
     IGEGAIRKSI QEQLTVLKDD CPTILGDYPS LIGEIGIPFD MDDRWSYGYT DNGKGLGNYK
     NQQKALDASL NACDGSNALN YTLWTYCPDN SHEWGDGWNL EDLSIWSVDD LRSHRKPGSD
     AFASHAAVVR NHEAPGTPPP EPVTLPGSSA LNLAAVLPSP SSSNDKTLGD ITSIGGWDNA
     WDFLTDGARA AAAFVRPYPM AIVGVPVHWE LNAGKASFTF TVRVSAEDAA PEDDECNPPT
     EIYVPLVHFA SDKTLMGIWA DDDGEQNEDK NSSRTATPAV GQSATASQVD LSSMPPSNSG
     SKDDLSLHKL HHFQARMPGT TNDNSEVTLL ASHADPHLAV DVRVSDGRWE MTGQTLRWWY
     RVPSREEGSV EYKIEVKRQG GPIKLNELGR PVRRASGQSR SWSAVCSDLL DCFS
//