ID A0A166B9Q7_9AGAM Unreviewed; 1739 AA.
AC A0A166B9Q7;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Ketoacyl-synt-domain-containing protein {ECO:0000313|EMBL:KZV64746.1};
GN ORFNames=PENSPDRAFT_756992 {ECO:0000313|EMBL:KZV64746.1};
OS Peniophora sp. CONT.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Russulales; Peniophoraceae; Peniophora.
OX NCBI_TaxID=1314672 {ECO:0000313|EMBL:KZV64746.1, ECO:0000313|Proteomes:UP000077086};
RN [1] {ECO:0000313|EMBL:KZV64746.1, ECO:0000313|Proteomes:UP000077086}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CONT {ECO:0000313|EMBL:KZV64746.1,
RC ECO:0000313|Proteomes:UP000077086};
RX PubMed=26659563; DOI=10.1093/molbev/msv337;
RA Nagy L.G., Riley R., Tritt A., Adam C., Daum C., Floudas D., Sun H.,
RA Yadav J.S., Pangilinan J., Larsson K.H., Matsuura K., Barry K., Labutti K.,
RA Kuo R., Ohm R.A., Bhattacharya S.S., Shirouzu T., Yoshinaga Y.,
RA Martin F.M., Grigoriev I.V., Hibbett D.S.;
RT "Comparative Genomics of Early-Diverging Mushroom-Forming Fungi Provides
RT Insights into the Origins of Lignocellulose Decay Capabilities.";
RL Mol. Biol. Evol. 33:959-970(2016).
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DR EMBL; KV424640; KZV64746.1; -; Genomic_DNA.
DR STRING; 1314672.A0A166B9Q7; -.
DR InParanoid; A0A166B9Q7; -.
DR OrthoDB; 5396558at2759; -.
DR Proteomes; UP000077086; Unassembled WGS sequence.
DR GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:InterPro.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
DR GO; GO:0009403; P:toxin biosynthetic process; IEA:UniProt.
DR CDD; cd00833; PKS; 1.
DR Gene3D; 3.30.70.3290; -; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR Gene3D; 1.10.1200.10; ACP-like; 2.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR Gene3D; 3.40.366.10; Malonyl-Coenzyme A Acyl Carrier Protein, domain 2; 1.
DR Gene3D; 3.10.129.110; Polyketide synthase dehydratase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR001227; Ac_transferase_dom_sf.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR014043; Acyl_transferase.
DR InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR InterPro; IPR018201; Ketoacyl_synth_AS.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR016036; Malonyl_transacylase_ACP-bd.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR042104; PKS_dehydratase_sf.
DR InterPro; IPR020807; PKS_DH.
DR InterPro; IPR049551; PKS_DH_C.
DR InterPro; IPR049552; PKS_DH_N.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR020802; PKS_thioesterase.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR InterPro; IPR030918; PT_fungal_PKS.
DR InterPro; IPR001031; Thioesterase.
DR InterPro; IPR016039; Thiolase-like.
DR NCBIfam; TIGR04532; PT_fungal_PKS; 1.
DR PANTHER; PTHR43775; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR43775:SF37; FATTY ACID SYNTHASE; 1.
DR Pfam; PF00698; Acyl_transf_1; 1.
DR Pfam; PF00109; ketoacyl-synt; 1.
DR Pfam; PF02801; Ketoacyl-synt_C; 1.
DR Pfam; PF21089; PKS_DH_N; 1.
DR Pfam; PF00550; PP-binding; 2.
DR Pfam; PF14765; PS-DH; 1.
DR Pfam; PF00975; Thioesterase; 1.
DR SMART; SM00827; PKS_AT; 1.
DR SMART; SM00826; PKS_DH; 1.
DR SMART; SM00825; PKS_KS; 1.
DR SMART; SM00823; PKS_PP; 2.
DR SMART; SM00824; PKS_TE; 1.
DR SUPFAM; SSF47336; ACP-like; 2.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR SUPFAM; SSF52151; FabD/lysophospholipase-like; 1.
DR SUPFAM; SSF55048; Probable ACP-binding domain of malonyl-CoA ACP transacylase; 1.
DR SUPFAM; SSF53901; Thiolase-like; 1.
DR PROSITE; PS50075; CARRIER; 2.
DR PROSITE; PS00606; KS3_1; 1.
DR PROSITE; PS52004; KS3_2; 1.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 2.
PE 4: Predicted;
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000077086};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 26..454
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
FT DOMAIN 1275..1351
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 1375..1449
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
SQ SEQUENCE 1739 AA; 189369 MW; FE538F60E4A327E0 CRC64;
MSTYNQAAVF DPAVPAEHAI PAAPHHESIA IVGMAVNMPG APDASRLWGI LEHGINTVAE
IPGHRFKVSN YEEADTGRAA RTMKARTGNF IDDPEGFDAA FFKISPREAR SMDPQARILL
HTAYEALEDA GYVPSATPSF APETFGCYVG VATGDYTQNL RKDIDVYYST GTLRAFLSGR
ISYVFKWGGP SVVLDTACSS SMVSIYQACR ALTSHDCNAA MAGGVNVITS PDMFLGLDRG
HFLSPTGQCK AFDASADGYS RGEGCGLFVL KRLSDALAEN DNILGVIRGV EVNQSGLAHS
ITHPHAPTQA RLFRRLLERS GVNASRVNVV EAHGTGTQAG DPNELESIRN VLSVGRDAEN
PLHVTSVKAN IGHLEAASGA ASLAKLLLML KHGTIPRQIS LCNLNPRVTN LVRDHIVIDR
EQVPWQPVHE GERRMALLNN FGAAGSNTAL LLEEYVADPV CAPDTASTFV FGISAKSPET
LLRLRDAYVQ WLQRDEHQDT RLVDIAYTAT ARRIVYDYRF AVTASSKKEL VEKLTTSNSA
SPSRVPKKIA FVFSGQGGKY RGMGSTLYRT SSLFREIVDE CHSFLVDSGF PGVLQVLYPK
RSPADISQEE EFEINQSAIF VLEYGMARLW LSWGVEPAAV VGHSLGEYVA QVVSGVLLLK
DALTLIANRV RLMVTQCATG STSMLAVNVG RSELEGILAS SSSFADLSIA CCNSPTDTVV
SGPVRALKEL KVHLDSEVHV KHVMLSVPFG YHSRAMDIIF PDLLAMGQRV TVRPPSIAIV
SNVLGQVVMP GTQGVFTPDY YARHCSDPVR FEQGITSLCQ ANGFDDISVW IEIGPHSSTL
PMLKAHPLVR DDAVLIPSLR RKQDAWATLS SALAQLYLTS NTIRWRDTFT HVDARCTHLP
AYPWSKTKFW VAFEEDSLAT GALTTNSKPL GTALVQKHAM LHRWVRSPNL ESEPTAVFEA
PVASLARAIT GHKVGGVALC PASVYGELAL AGIDAATERL GLVTDDFVVT LRDTEFTRPL
IFDAGIERKV YTSITLASGD TGSWHVSSRV DERSEDVHSV GTFKRQPNKK IVTKFTRAAP
MVLRQIAVVQ AALDAESFST RTVYDIIFPR VVEYGNEYRT IRSLRISSDG MEGYAVVQLP
DDHDRQRFVI HPTFLDTLFH VAGFAANIRG DKGDAYICSR VEKIMALPQL VDPAARYGVY
FRNIWFSEER TILAESYAIE LDGQRRVVAH VKGIHFRRVL LSGLERSFTF AAGGHARPPL
HRNERYLSST HKPSQSTVEA ETIVKQLVAK TCDIPNIDPF VDLDTYGVDS LMSIEICHKL
IQAFPTVALD ANVLQSCTTV AQLIEAVVRR LPACLQTATP PSTTSVATRS QPQSVATSAD
ARAIIATTLG VSVYELADEV DLDALGLDSL TAIEATMALQ TAFARSLPKT LFESVKTVKD
ALDVISYTTR STDIGNATQF ALTPPHTPAH DALEPMLIAP ETRARLTKSL RLDEIPVLLQ
AGTGTPLFLV HDGSGVVSYL KRVEPLGRAL WGLNNPHFLD GTSWDSLETM AGAYARQILE
TIGGTGPVIL GGWSFGGVVA FEAARQLRAL GAPVRGVLLI DSPPPRGHVP FDDTLITAIA
SADGRSPTND LTRLVSRQFE LSSRLLGAYG ANALEGPFEE RVVLLRSREG YRTVNHEVQV
PQWIADRTDT GVVVDGWEEM LGYRIKVLPI PGNHFEVFAP QTMAQLSETI AGAADYLDE
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