ID A0A166BSU2_DAUCS Unreviewed; 827 AA.
AC A0A166BSU2;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=CSC1/OSCA1-like 7TM region domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=DCAR_011578 {ECO:0000313|EMBL:KZN02822.1};
OS Daucus carota subsp. sativus (Carrot).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Apiales; Apiaceae; Apioideae; Scandiceae; Daucinae;
OC Daucus; Daucus sect. Daucus.
OX NCBI_TaxID=79200 {ECO:0000313|EMBL:KZN02822.1, ECO:0000313|Proteomes:UP000077755};
RN [1] {ECO:0000313|EMBL:KZN02822.1, ECO:0000313|Proteomes:UP000077755}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. DH1 {ECO:0000313|Proteomes:UP000077755};
RC TISSUE=Leaf {ECO:0000313|EMBL:KZN02822.1};
RX PubMed=27158781; DOI=10.1038/ng.3565;
RA Iorizzo M., Ellison S., Senalik D., Zeng P., Satapoomin P., Huang J.,
RA Bowman M., Iovene M., Sanseverino W., Cavagnaro P., Yildiz M.,
RA Macko-Podgorni A., Moranska E., Grzebelus E., Grzebelus D., Ashrafi H.,
RA Zheng Z., Cheng S., Spooner D., Van Deynze A., Simon P.;
RT "A high-quality carrot genome assembly provides new insights into
RT carotenoid accumulation and asterid genome evolution.";
RL Nat. Genet. 48:657-666(2016).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CSC1 (TC 1.A.17) family.
CC {ECO:0000256|ARBA:ARBA00007779}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KZN02822.1}.
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DR EMBL; LNRQ01000003; KZN02822.1; -; Genomic_DNA.
DR RefSeq; XP_017242890.1; XM_017387401.1.
DR AlphaFoldDB; A0A166BSU2; -.
DR STRING; 79200.A0A166BSU2; -.
DR EnsemblPlants; KZN02822; KZN02822; DCAR_011578.
DR GeneID; 108215068; -.
DR Gramene; KZN02822; KZN02822; DCAR_011578.
DR KEGG; dcr:108215068; -.
DR OMA; EEYPLEH; -.
DR OrthoDB; 459972at2759; -.
DR Proteomes; UP000077755; Chromosome 3.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005227; F:calcium-activated cation channel activity; IEA:InterPro.
DR GO; GO:0006623; P:protein targeting to vacuole; IEA:EnsemblPlants.
DR InterPro; IPR045122; Csc1-like.
DR InterPro; IPR003864; CSC1/OSCA1-like_7TM.
DR InterPro; IPR027815; CSC1/OSCA1-like_cyt.
DR InterPro; IPR032880; Csc1/OSCA1-like_N.
DR PANTHER; PTHR13018:SF114; EXPRESSED PROTEIN; 1.
DR PANTHER; PTHR13018; PROBABLE MEMBRANE PROTEIN DUF221-RELATED; 1.
DR Pfam; PF14703; PHM7_cyt; 1.
DR Pfam; PF02714; RSN1_7TM; 2.
DR Pfam; PF13967; RSN1_TM; 1.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023303};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000077755};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 46..67
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 116..137
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 161..182
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 413..436
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 471..492
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 508..527
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 568..590
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 681..711
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 744..762
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 72..179
FT /note="CSC1/OSCA1-like N-terminal transmembrane"
FT /evidence="ECO:0000259|Pfam:PF13967"
FT DOMAIN 211..400
FT /note="CSC1/OSCA1-like cytosolic"
FT /evidence="ECO:0000259|Pfam:PF14703"
FT DOMAIN 411..596
FT /note="CSC1/OSCA1-like 7TM region"
FT /evidence="ECO:0000259|Pfam:PF02714"
FT DOMAIN 673..760
FT /note="CSC1/OSCA1-like 7TM region"
FT /evidence="ECO:0000259|Pfam:PF02714"
SQ SEQUENCE 827 AA; 93384 MW; 4C3B892CD1EE5AA1 CRC64;
MKFANPRLLI MQFQPPKASP IEFNLNSISP SNDDSDDFNF AWYGNIQYLI NISAIGTITC
ILIFVLLKLR SDHRRLPGPT AIASKLLAVW HATGRQISLH CGADAAQFLL IEGGSCALLV
SLAFLDVSVL LPLNIYAGNA PMADQFSKTT ITHITKGSSL LWVHFVFVVI VVVIVHFAIN
LIERKLKVTR FRDGNGNPSD PGVNNSSTAI FTVMVLGVPK NLGFDKTPFV EYFQHKYPGK
VYRVIVPMDL CALDDLVTEL VKVREDISKL VRKMELRDLG EDYYESEYGL HGSWRRVKDL
WGRFVDELGL SNEEKLRKLQ ERRADLEMDM AAYKEGRAKG AGVAFVVFKD VYTTNKAVQD
FRNEKKRRVG KFFSVMELQL QKNHWKVDRA PLATDLYWNH LGSTKLSLKL RRVFVNTCLL
LLLLFFSSPL AVITAIKSAG RIINAEAMDN AQIWFAWIQS SSWLATLFFQ FLPNVLIFVS
MYIVIPSALY YLSKFERHLT VSGEQRAALL KMVCFFLVNL ILLRALVESS LESAILSMGR
CYLDGEDCKR IEEYMSASFL SRSCLSSVAF LIISTFLGIS FDLLAPIPWI KRKIQKFQKN
DMLQLVPENS EDYALESSDT ESLQRPLMHD GMFNTAVGNG GSVNGGSGSS EIDIPGQDLS
EYPISRTSPV PKQTFDFAQY YAFNLTIFAL TLIYSSFAPL VVPVGAIYFG YRYVVDKYNF
LFVYRVQGFP AGNDGRLMDT VLSIMRFCVD LFLLSMLLFF SVKGDSTKLQ AIFTLGLLVM
YKILPSDNDG FQPALLQGMQ TVDNIVEGPI DYEVFSQPKF EWDTYNL
//
