ID A0A166C4N0_9EURY Unreviewed; 254 AA.
AC A0A166C4N0;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE RecName: Full=Large ribosomal subunit protein uL4 {ECO:0000256|HAMAP-Rule:MF_01328};
GN Name=rplD {ECO:0000313|EMBL:KZX11197.1};
GN Synonyms=rpl4 {ECO:0000256|HAMAP-Rule:MF_01328};
GN ORFNames=MBCUR_14690 {ECO:0000313|EMBL:KZX11197.1};
OS Methanobrevibacter curvatus.
OC Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC Methanobacteriales; Methanobacteriaceae; Methanobrevibacter.
OX NCBI_TaxID=49547 {ECO:0000313|EMBL:KZX11197.1, ECO:0000313|Proteomes:UP000077245};
RN [1] {ECO:0000313|EMBL:KZX11197.1, ECO:0000313|Proteomes:UP000077245}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 11111 {ECO:0000313|EMBL:KZX11197.1,
RC ECO:0000313|Proteomes:UP000077245};
RA Poehlein A., Seedorf H., Daniel R.;
RT "Genome sequence of Methanobrevibacter curvatus DSM 11111.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Forms part of the polypeptide exit tunnel.
CC {ECO:0000256|HAMAP-Rule:MF_01328}.
CC -!- FUNCTION: One of the primary rRNA binding proteins, this protein
CC initially binds near the 5'-end of the 23S rRNA. It is important during
CC the early stages of 50S assembly. It makes multiple contacts with
CC different domains of the 23S rRNA in the assembled 50S subunit and
CC ribosome. {ECO:0000256|HAMAP-Rule:MF_01328}.
CC -!- SUBUNIT: Part of the 50S ribosomal subunit. {ECO:0000256|HAMAP-
CC Rule:MF_01328}.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uL4 family.
CC {ECO:0000256|ARBA:ARBA00010528, ECO:0000256|HAMAP-Rule:MF_01328}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KZX11197.1}.
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DR EMBL; LWMV01000191; KZX11197.1; -; Genomic_DNA.
DR RefSeq; WP_067092099.1; NZ_LWMV01000191.1.
DR AlphaFoldDB; A0A166C4N0; -.
DR STRING; 49547.MBCUR_14690; -.
DR PATRIC; fig|49547.3.peg.1570; -.
DR OrthoDB; 10737at2157; -.
DR Proteomes; UP000077245; Unassembled WGS sequence.
DR GO; GO:1990904; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
DR GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR Gene3D; 3.40.1370.10; -; 1.
DR HAMAP; MF_01328_A; Ribosomal_L4_A; 1.
DR InterPro; IPR002136; Ribosomal_uL4.
DR InterPro; IPR023574; Ribosomal_uL4_dom_sf.
DR InterPro; IPR013000; Ribosomal_uL4_euk/arc_CS.
DR InterPro; IPR045240; Ribosomal_uL4_euk/arch.
DR InterPro; IPR019970; Ribosomall_uL4-arc.
DR NCBIfam; TIGR03672; rpl4p_arch; 1.
DR PANTHER; PTHR19431; 60S RIBOSOMAL PROTEIN L4; 1.
DR PANTHER; PTHR19431:SF0; 60S RIBOSOMAL PROTEIN L4; 1.
DR Pfam; PF00573; Ribosomal_L4; 1.
DR SUPFAM; SSF52166; Ribosomal protein L4; 1.
DR PROSITE; PS00939; RIBOSOMAL_L1E; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000077245};
KW Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274, ECO:0000256|HAMAP-
KW Rule:MF_01328};
KW Ribosomal protein {ECO:0000256|ARBA:ARBA00022980, ECO:0000256|HAMAP-
KW Rule:MF_01328}; RNA-binding {ECO:0000256|HAMAP-Rule:MF_01328};
KW rRNA-binding {ECO:0000256|HAMAP-Rule:MF_01328}.
FT REGION 45..66
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 254 AA; 28035 MW; 95309A9EB162E93A CRC64;
MKVNVYSIEG EVVEEIELPK IFNEEFRPDL IKRAVISSQT ARVQPWGTDP MAGKRTSAKS
WGSGRGAAMV PRIKNGSKAA FIPQAIGGRR AHPPRPVKTY KEKINIKERR FAIRSAVAAT
SKSELVANRG HKVENVPQFP IIVDDEFSSI KKTKETRQIF EKLGLIDDLT RAKNSKKIKS
GKGKLRGRKY RTAKGPLVVV GEDKGINLAV RNYPGVDVVN VENLNAELLA PGTHPGRLTL
FTKSAIEKLG GLFQ
//
