ID   A0A166CKP0_9EURY        Unreviewed;       434 AA.
AC   A0A166CKP0;
DT   06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT   06-JUL-2016, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   SubName: Full=Divalent cation transporter {ECO:0000313|EMBL:KZX14611.1};
GN   ORFNames=MBCUT_20010 {ECO:0000313|EMBL:KZX14611.1};
OS   Methanobrevibacter cuticularis.
OC   Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC   Methanobacteriales; Methanobacteriaceae; Methanobrevibacter.
OX   NCBI_TaxID=47311 {ECO:0000313|EMBL:KZX14611.1, ECO:0000313|Proteomes:UP000077275};
RN   [1] {ECO:0000313|EMBL:KZX14611.1, ECO:0000313|Proteomes:UP000077275}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 11139 {ECO:0000313|EMBL:KZX14611.1,
RC   ECO:0000313|Proteomes:UP000077275};
RA   Poehlein A., Seedorf H., Daniel R.;
RT   "Genome sequence of Methanobrevibacter cuticularis DSM 11139.";
RL   Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the SLC41A transporter family.
CC       {ECO:0000256|ARBA:ARBA00009749}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KZX14611.1}.
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DR   EMBL; LWMW01000158; KZX14611.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A166CKP0; -.
DR   STRING; 47311.MBCUT_20010; -.
DR   PATRIC; fig|47311.3.peg.2186; -.
DR   OrthoDB; 86118at2157; -.
DR   Proteomes; UP000077275; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 1.10.357.20; SLC41 divalent cation transporters, integral membrane domain; 2.
DR   InterPro; IPR006667; SLC41_membr_dom.
DR   InterPro; IPR036739; SLC41_membr_dom_sf.
DR   InterPro; IPR045349; SLC41A1-3.
DR   PANTHER; PTHR16228; DIVALENT CATION TRANSPORTER SOLUTE CARRIER FAMILY 41; 1.
DR   PANTHER; PTHR16228:SF7; SOLUTE CARRIER FAMILY 41 MEMBER 1-LIKE PROTEIN; 1.
DR   Pfam; PF01769; MgtE; 2.
DR   SUPFAM; SSF161093; MgtE membrane domain-like; 2.
PE   3: Inferred from homology;
KW   Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW   Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000077275};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        6..25
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        46..70
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        116..138
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        158..180
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        192..220
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        226..244
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        260..283
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        330..351
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        363..390
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        411..433
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          80..210
FT                   /note="SLC41A/MgtE integral membrane"
FT                   /evidence="ECO:0000259|Pfam:PF01769"
FT   DOMAIN          292..423
FT                   /note="SLC41A/MgtE integral membrane"
FT                   /evidence="ECO:0000259|Pfam:PF01769"
SQ   SEQUENCE   434 AA;  46801 MW;  E0706F6970E6FC81 CRC64;
     MLVLFIVNSI LFLYEKLEML CSLVYSAINR FNSFFKDSNS VIKEGLIALL ICAIGDLFAG
     IILGNMTFFL ETFPGLMVLI PGAIGMRGNI FGALGSRLGS NLHIGLISPK LKRSKILTEN
     ILSSLILTLI LSLFLAFLAK GICTLFNFDS MSLLDFTLIS VFAGLISSVI MLPLTMLISL
     KSFKNGWDPD NISTPLIAAF GDLFTLPSII LSLIIVSLLS HVLLKYSLFI LAIIITIIVF
     IYAIRSEGEM RDIVMQSTPV LLLSSVLGVS AGGFLNSSIS VLLKNPSLLT LVPLFSGESG
     NLVSILGARL SSALHAGLIE PVLKPEKTSV NNFLIIVVLA IIIYPIIGFL AEASSRLLNF
     PGIGFFSILS ISTVSGMILI GIMILIVFFI SSISYRKGFN PDNIVIPIST SITDSISSLI
     LVTVALAVLH IFVI
//