ID A0A166FQQ9_DAUCS Unreviewed; 2707 AA.
AC A0A166FQQ9;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE RecName: Full=DNA-directed DNA polymerase {ECO:0008006|Google:ProtNLM};
GN ORFNames=DCAR_000737 {ECO:0000313|EMBL:KZN08068.1};
OS Daucus carota subsp. sativus (Carrot).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Apiales; Apiaceae; Apioideae; Scandiceae; Daucinae;
OC Daucus; Daucus sect. Daucus.
OX NCBI_TaxID=79200 {ECO:0000313|EMBL:KZN08068.1, ECO:0000313|Proteomes:UP000077755};
RN [1] {ECO:0000313|EMBL:KZN08068.1, ECO:0000313|Proteomes:UP000077755}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. DH1 {ECO:0000313|Proteomes:UP000077755};
RC TISSUE=Leaf {ECO:0000313|EMBL:KZN08068.1};
RX PubMed=27158781; DOI=10.1038/ng.3565;
RA Iorizzo M., Ellison S., Senalik D., Zeng P., Satapoomin P., Huang J.,
RA Bowman M., Iovene M., Sanseverino W., Cavagnaro P., Yildiz M.,
RA Macko-Podgorni A., Moranska E., Grzebelus E., Grzebelus D., Ashrafi H.,
RA Zheng Z., Cheng S., Spooner D., Van Deynze A., Simon P.;
RT "A high-quality carrot genome assembly provides new insights into
RT carotenoid accumulation and asterid genome evolution.";
RL Nat. Genet. 48:657-666(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KZN08068.1}.
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DR EMBL; LNRQ01000001; KZN08068.1; -; Genomic_DNA.
DR STRING; 79200.A0A166FQQ9; -.
DR EnsemblPlants; KZN08068; KZN08068; DCAR_000737.
DR Gramene; KZN08068; KZN08068; DCAR_000737.
DR Proteomes; UP000077755; Chromosome 1.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:InterPro.
DR GO; GO:0006261; P:DNA-templated DNA replication; IEA:InterPro.
DR GO; GO:0050896; P:response to stimulus; IEA:UniProt.
DR CDD; cd18026; DEXHc_POLQ-like; 2.
DR CDD; cd08638; DNA_pol_A_theta; 1.
DR CDD; cd18795; SF2_C_Ski2; 1.
DR Gene3D; 1.10.3380.20; -; 1.
DR Gene3D; 3.30.70.370; -; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR001098; DNA-dir_DNA_pol_A_palm_dom.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR002298; DNA_polymerase_A.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR046931; HTH_61.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR048960; POLQ-like_helical.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR10133; DNA POLYMERASE I; 1.
DR PANTHER; PTHR10133:SF62; DNA POLYMERASE THETA; 1.
DR Pfam; PF00270; DEAD; 2.
DR Pfam; PF00476; DNA_pol_A; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF20470; HTH_61; 1.
DR Pfam; PF21099; POLQ_helical; 1.
DR PRINTS; PR00868; DNAPOLI.
DR SMART; SM00487; DEXDc; 2.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00482; POLAc; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR SUPFAM; SSF158702; Sec63 N-terminal domain-like; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 2.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000077755}.
FT DOMAIN 524..718
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 1061..1255
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 1295..1487
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 109..142
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 665..690
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1202..1223
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1991..2014
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..18
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 668..687
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1205..1223
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2707 AA; 298821 MW; B13E0408E8C02697 CRC64;
MASNSPRSRV NQFYASKKKS KGASPLLKSK LVEKDARVTL DASPSGKGSL EGFLVTSQDD
LPPAGSLQTA NCSSARTDFV KRKLELDVRL SSKDENEEVY LGGEGPCQMA KASGEAQQKK
LKTSDVGDFS SKGLGKDTSD SSYGLKNPEL KQFAADFLSL YCSKEVPPCT AKRQGSPSSI
ASEEKLQKRR HFSNDECQYL TKGEETCSGE KFNEQVQRQP NVIAKSEVAA NNFSREVIVN
DSSINFRGSL KKCENTLVDM ACCGTPGPLI SNGGARETPK SMHGSSIFSP GETFWNEAVK
IADGLLAVNK NIPVKVVQQI KDTDKSCKTR NLDMLTDEHH PKQSNVIEYE GPKRICDAGS
ASLALRRENE NNLEKVVSPM PVKHFDFSSE EKAYQKEAQS DQSEHILKAD EQGRCYSTNH
KPLQRGHIAS QMSNELPELH VSTSQKIVDN LLGVNASSTS NTPNNEFRFS SATHSCSEEL
TPSSFLSPKD RLDIINWLPS EICNTYRKRG ISKLYPWQVD CLQVDGVLQR RNLVYCASTS
AGKSFVAEIL MLRRVLSTGK MALLVLPYVS ICAEKAEHLE ALLEPLDKHV RSYYGNQGGG
TLPKDTSVAV CTIEKANSLL NRLLEEGRMS EVGIIVIDEL HMVGDQSRGY LLELMLTKLR
YAAGDGSTEL SSGESSATST TSGKNDPAHG LQIVGMSATL PNVAAVADWL QGSPSSIASE
EKLQKRRHFS NDECQYLTKG EETCSGEKFN EQVQRQPNVI AKSEVAANNF SREVIVNDSS
INFRGSLKKC ENTLVDMACC GTPGPLISNG GARETPKSMH GSSIFSPGET FWNEAVKIAD
GLLAVNKNIP VKVVQQIKDT DKSCKTRNLD MLTDEHHPKQ SNVIEYEGPK RICDAGSASL
ALRRENENNL EKVVSPMPVK HFDFSSEEKA YQKEAQSDQS EHILKADEQG RCYSTNHKPL
QRGHIASQMS NELPELHVST SQKIVDNLLG VNASSTSNTP NNEFRFSSAT HSCSEELTPS
SFLSPKDRLD IINWLPSEIC NTYRKRGISK LYPWQVDCLQ VDGVLQRRNL VYCASTSAGK
SFVAEILMLR RVLSTGKMAL LVLPYVSICA EKAEHLEALL EPLDKHVRSY YGNQGGGTLP
KDTSVAVCTI EKANSLLNRL LEEGRMSEVG IIVIDELHMV GDQSRGYLLE LMLTKLRYAA
GDGSTELSSG ESSATSTTSG KNDPAHGLQI VGMSATLPNV AAVADWLQAA LYQTDFRPVP
LVEYIKVGNT IYNKSMEIIR TIAKGAELGG KDPDHIVQLC NEVVQEGHSV LMFCSSRKGC
ESTAAHIAKY LKKFSANSCS DQTEFSDINS AIDTLRRSPA GLDPVLETTL PSGVAYHHAG
LTVEEREVVE SCYRKGLVRV LTATSTLAAG VNLPARRVIF RQPRIGRDFI DGTRYRQMSG
RAGRTGIDTK GESVLICKPE EVKRILGLIN DSCPPLHSCL SEDKNGMTHA ILEVVSGGIV
QTARDIHCYV RCTLLNSTKP FEDVVRSAQD SLRWLCQKKF LEWSEDTKLY SSTPLGRASF
GSSLCPEESL IVLDDLSRAR EGFVLASDLH LVYLVTPINV DVEPDWELYY ERFMELSPLD
QSVGNRVGVQ EPFLMRMAHG APVRTSNRSR DITKGFQGRS ETRHGVLSHG MLSDDQSLRV
CKRFYVALIL SRLVQEIPVT EVCGAFKVAR GMVQALQENA GRFASMVSVF CERLGWHDLE
GLVAKFQNRV SFGVRAEIVE LTTIPFVKGS RARALYKAGL RTPQAIAESP IPEIVKALFE
SSAWAAEEGS AQRRIQMGVA KKIKNGARKI VLDKAEEARV AAFSAFKSLG LEVPHFPPAQ
LPTAAGSASR KERSTSPVEE AMSSIILEHG KPISTRQSLE MRTIKDKVSS DAGEVPKKLS
DGGIEIPGAA SEVGNMHDAK NIAVGGKEST TYEFKSSVNC ISNTETAVSS PLKATAAGNR
LDNKCVNNIR PNPGLEGNES HYGKDTASEK GPINAAKTPG GFESFLDVWD SREDFFFDIH
FNKRSEFNSL APFEIHGVAI CWENSPVYYI NLPKDLFSSE NESNNNVSVN MSNSKKNLFA
QKQLIEVAKR RWDRISRILG REDVRKFGWN MKIQIQALKN PAFSIQRFVG LNLGSKSLGL
ELVDSSYYMF SPIHVKRGVD LCIVAWILWP DEERSSNPNL EKEVKKRLSS EAAAAASRCS
RWKNQMRQAA HNGCCRRVAL SRALYSVLWK LLTSEELMEA LLTIESPLVN ILADMELCGI
GVDMEGCIRA RHLLGRKLKC LEKEAHRLAG MTFSLYATAD IANVLYQRLK LPIPEGYNKG
KQHPSTDKHC LELLRHEHPI IAIIKEHRTL AKLLNSTLGS ICSLARLSMR TQKYTLHGHW
LQTSTATGRL SMEEPNLQCV EHMVDFQMSD SEKGECTDGD NYRISPRDFF VPTQENWLLL
AADYSQIELR LMAHFSKDPS LVELLSKRKS DVFRIIAAKW TGKMESSVSS IEREQTKKLI
YGILYGMGAN SLAEQLECSS EDAAEKIQSF KRSFQGVASW LREAVISCRQ KGYVETLKGR
KRFLANIKFG NSKEKSKAER QAVNSICQGS AADIIKIAMI NLHSALVQDV SGSDLSTSLE
GSHLKGRCRI LLQVHDELVL EADPSVMKEA GLLLQKTMES AATLLVPLHV KLQVGRTWGT
LEPFSLE
//
