ID A0A166FY80_9AGAM Unreviewed; 1366 AA.
AC A0A166FY80;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=Ras GTPase-activating protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=FIBSPDRAFT_747344 {ECO:0000313|EMBL:KZP17291.1};
OS Fibularhizoctonia sp. CBS 109695.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Atheliales; Atheliaceae; Fibularhizoctonia.
OX NCBI_TaxID=436010 {ECO:0000313|EMBL:KZP17291.1, ECO:0000313|Proteomes:UP000076532};
RN [1] {ECO:0000313|EMBL:KZP17291.1, ECO:0000313|Proteomes:UP000076532}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 109695 {ECO:0000313|EMBL:KZP17291.1,
RC ECO:0000313|Proteomes:UP000076532};
RX PubMed=26659563; DOI=10.1093/molbev/msv337;
RA Nagy L.G., Riley R., Tritt A., Adam C., Daum C., Floudas D., Sun H.,
RA Yadav J.S., Pangilinan J., Larsson K.H., Matsuura K., Barry K., Labutti K.,
RA Kuo R., Ohm R.A., Bhattacharya S.S., Shirouzu T., Yoshinaga Y.,
RA Martin F.M., Grigoriev I.V., Hibbett D.S.;
RT "Comparative Genomics of Early-Diverging Mushroom-Forming Fungi Provides
RT Insights into the Origins of Lignocellulose Decay Capabilities.";
RL Mol. Biol. Evol. 33:959-970(2016).
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DR EMBL; KV417584; KZP17291.1; -; Genomic_DNA.
DR STRING; 436010.A0A166FY80; -.
DR OrthoDB; 12619at2759; -.
DR Proteomes; UP000076532; Unassembled WGS sequence.
DR GO; GO:0016043; P:cellular component organization; IEA:UniProt.
DR CDD; cd21206; CH_IQGAP; 1.
DR Gene3D; 1.20.5.190; -; 1.
DR Gene3D; 1.10.418.10; Calponin-like domain; 1.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR000593; RasGAP_C.
DR InterPro; IPR001936; RasGAP_dom.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR PANTHER; PTHR14149:SF14; PATTERNED EXPRESSION SITE; 1.
DR PANTHER; PTHR14149; RAS GTPASE-ACTIVATING PROTEIN WITH IQ MOTIF; 1.
DR Pfam; PF00307; CH; 1.
DR Pfam; PF00612; IQ; 2.
DR Pfam; PF00616; RasGAP; 1.
DR Pfam; PF03836; RasGAP_C; 1.
DR SMART; SM00015; IQ; 11.
DR SMART; SM00323; RasGAP; 1.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR SUPFAM; SSF143885; RGC domain-like; 1.
DR PROSITE; PS50021; CH; 1.
DR PROSITE; PS50096; IQ; 9.
DR PROSITE; PS50018; RAS_GTPASE_ACTIV_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000076532}.
FT DOMAIN 1..84
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 722..923
FT /note="Ras-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50018"
FT COILED 1193..1220
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1366 AA; 156636 MW; 8A42DCA7B22A8107 CRC64;
MEEGMRNGVV LAKLVRAFQG EKVVRRIYEA PKLDFRHSDN INVFFNFVRE VGLPEGFIFE
LTDLYNKKNL PKVIYCIHAL SHLLARRGLA QRIGNLIGQL KFSDDQLHAT QKGLKDAGVA
MPNFGNIGKE LAKDLNEEPE VEVETEEEVR DRLLSEAEPS IIATQQICRG FLVRKAQATQ
HIQLRLAERY LPKLQGHCRA FLTRQRVQVQ RQEQTDLTPW AMALQASIRA SAQYVIKVQA
QGRGVIQRRR FAQLHAAMKR STFSVVKLQS LARARVTRNA HKEVKKTFSK PQVFHSIVGL
QAQARGLLAR RKVAKQMQAL QRFVKSFSKL EAQSRGVLVR RQMRKQMAKL EDVSSTVIRI
QAAARTYLAR KRLLMLIRSL RKATPMLIGL QARARANLAR QEHKNVSKAL SEVNVVSGVN
TFQALARAAI TRNRHREQAK SLEFVAPDVV GFQATARGYL IRCDFYAWRD HLWRSQPIAT
IMQAMLRGVL QRRRFRAKME YFHANLNKVV KIQSLFRAKE TREQYRQLTL GKNVSVGTIK
NFVHLLDDSE TDFQEEIKIE RLRKRVVEGI RENQALESDV SDLDVKIALV VQNVKSFEEL
IKARRLYGAD NAAAHATRAS ILAAHGDPFA GTSSLDQSAK RKLELYKQLF YLLQTEPHYL
SRLFLRMSIE DTPEKNRRLT ERVVLTLFGY GQDRREEFLL LKLFQVSWLM ICLENNFTTL
SVQEEIAAAN SISAVIHGHP MYINVAVHYV RPKQVAYVRE TLQAIIRDVI HSQELDLEID
PSIIHRGLIV AHEMRSGVAS ATPKDLPFAQ ALEDPNTRAE YIRRLQMLQK LTEAFFNVII
RSTKRMPYGM RLLARETLEA LQTSFPDATH EEYAACIGRI VYYRYINPAI ITPETFDIVT
KTVDVASRKN LAQISRVLTQ ITSGIEFGDD KPIYVPMNGY VRKAIDEMTA WLLEVADVPD
AEAHFQAHEF LDVTVQPKPI YISPNEVYSM HTLLSQHQDH LAIPEHVKNK QRVRGHSHAT
ARDDTLRVIL TELDGVPNLG NEELKDARDR AITLELSNRF ANVRDPEAEE KALWVQAKRG
VLAILRVQPA QDLVESLMRP VTDEEEELWE HVLEAEIENE QTRQVPRRQR SEAAGDSAYR
LEDIRSLTFK EVKAHAIFFL LELEKLGKIT RTDGFQGILN AIASDVRSKH RKRLQRQQEM
ANMNDALKHL KDRKKHFEEQ IDSYHNYVEA SMATMQRGKG KNRLTLPFTK QYFHLRDLQK
AGKSPQFGSF KYSCKSLYEK GILLSIDPYS PRQFDKLDMT MSSNKAGIFT IEVYNNTLGI
TNRLGSADLR MEDLLQAQFE NQASVSVCND LVKVNLQLFL YQINKK
//
