ID A0A166IC25_9MICO Unreviewed; 372 AA.
AC A0A166IC25;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE SubName: Full=IMP dehydrogenase {ECO:0000313|EMBL:TCO37089.1};
DE SubName: Full=Putative oxidoreductase {ECO:0000313|EMBL:KZX22126.1};
DE EC=1.-.-.- {ECO:0000313|EMBL:KZX22126.1};
GN ORFNames=ACH61_00771 {ECO:0000313|EMBL:KZX22126.1}, EV639_105177
GN {ECO:0000313|EMBL:TCO37089.1};
OS Rathayibacter tanaceti.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Rathayibacter.
OX NCBI_TaxID=1671680 {ECO:0000313|EMBL:KZX22126.1, ECO:0000313|Proteomes:UP000076717};
RN [1] {ECO:0000313|EMBL:TCO37089.1, ECO:0000313|Proteomes:UP000295366}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM Ac-2596 {ECO:0000313|EMBL:TCO37089.1,
RC ECO:0000313|Proteomes:UP000295366};
RX PubMed=26203337; DOI=.1186/s40793-015-0017-x;
RA Whitman W.B., Woyke T., Klenk H.P., Zhou Y., Lilburn T.G., Beck B.J.,
RA De Vos P., Vandamme P., Eisen J.A., Garrity G., Hugenholtz P.,
RA Kyrpides N.C.;
RT "Genomic Encyclopedia of Bacterial and Archaeal Type Strains, Phase III:
RT the genomes of soil and plant-associated and newly described type
RT strains.";
RL Stand. Genomic Sci. 10:26-26(2015).
RN [2] {ECO:0000313|EMBL:KZX22126.1, ECO:0000313|Proteomes:UP000076717}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM Ac-2596 {ECO:0000313|EMBL:KZX22126.1,
RC ECO:0000313|Proteomes:UP000076717};
RA Vasilenko O.V., Starodumova I.P., Tarlachkov S.V., Dorofeeva L.V.,
RA Evtushenko L.I.;
RT "Draft Genome Sequence of Rathayibacter sp. Strain VKM Ac-2596 Isolated
RT from Leaf Gall Induced by Plant-Parasitic Nematodes.";
RL Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:TCO37089.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=VKM Ac-2596 {ECO:0000313|EMBL:TCO37089.1};
RA Whitman W., Huntemann M., Clum A., Pillay M., Palaniappan K., Varghese N.,
RA Mikhailova N., Stamatis D., Reddy T., Daum C., Shapiro N., Ivanova N.,
RA Kyrpides N., Woyke T.;
RL Submitted (MAR-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the IMPDH/GMPR family.
CC {ECO:0000256|ARBA:ARBA00005502}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KZX22126.1}.
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DR EMBL; LIIN01000015; KZX22126.1; -; Genomic_DNA.
DR EMBL; SLWP01000005; TCO37089.1; -; Genomic_DNA.
DR RefSeq; WP_068208684.1; NZ_SLWP01000005.1.
DR AlphaFoldDB; A0A166IC25; -.
DR PATRIC; fig|1671680.3.peg.819; -.
DR OrthoDB; 9805398at2; -.
DR Proteomes; UP000076717; Unassembled WGS sequence.
DR Proteomes; UP000295366; Unassembled WGS sequence.
DR GO; GO:0003938; F:IMP dehydrogenase activity; IEA:InterPro.
DR GO; GO:0006164; P:purine nucleotide biosynthetic process; IEA:InterPro.
DR CDD; cd00381; IMPDH; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR005990; IMP_DH.
DR InterPro; IPR005992; IMP_DH-rel2.
DR InterPro; IPR001093; IMP_DH_GMPRt.
DR NCBIfam; TIGR01304; IMP_DH_rel_2; 1.
DR PANTHER; PTHR11911:SF111; INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE; 1.
DR PANTHER; PTHR11911; INOSINE-5-MONOPHOSPHATE DEHYDROGENASE RELATED; 1.
DR Pfam; PF00478; IMPDH; 1.
DR SMART; SM01240; IMPDH; 1.
DR SUPFAM; SSF51412; Inosine monophosphate dehydrogenase (IMPDH); 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000313|EMBL:KZX22126.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000076717}.
FT DOMAIN 14..296
FT /note="IMP dehydrogenase/GMP reductase"
FT /evidence="ECO:0000259|Pfam:PF00478"
SQ SEQUENCE 372 AA; 39023 MW; 84F4839257D37DC2 CRC64;
MEIEIGRAKR ARRAYAFDDI AVVPSRRTRD PEVVSVKWSI DAYQFATPIL AAPMDSVVSP
ATAITLGRLG ALGVLDLEGL WTRYEDPEPL LAEIRGLPAE AATARMQEIY SAPIRPELVT
ARLAEIRAAG VTVAGALSPQ RTAELYQTVV DAGVDVFVIR GTTVSAEHVS RDTEPLNLKK
FIYELDVPVI VGGASTYTAA LHLMRTGAAG VLVGFGGGAA STTRTTLGIQ APMATAVADV
AGARRDYLDE SGGRYVHVIA DGGLGTSGDI VKAVAVGADA VMLGSALARA TDAPGGGWHW
GAEAHHPQLP RGRRVQVGTV GTLEQVLYGP ATGADGTANL IGALRRSMAT TGYSDLKEFQ
RVEVVVAPYQ PS
//
