ID A0A166IJG2_9AGAM Unreviewed; 171 AA.
AC A0A166IJG2;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Phosphatidylglycerol/phosphatidylinositol transfer protein {ECO:0000256|ARBA:ARBA00016056};
GN ORFNames=SISSUDRAFT_1057339 {ECO:0000313|EMBL:KZT43803.1};
OS Sistotremastrum suecicum HHB10207 ss-3.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Trechisporales; Trechisporales incertae sedis; Sistotremastrum.
OX NCBI_TaxID=1314776 {ECO:0000313|EMBL:KZT43803.1, ECO:0000313|Proteomes:UP000076798};
RN [1] {ECO:0000313|EMBL:KZT43803.1, ECO:0000313|Proteomes:UP000076798}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HHB10207 ss-3 {ECO:0000313|EMBL:KZT43803.1,
RC ECO:0000313|Proteomes:UP000076798};
RX PubMed=26659563; DOI=10.1093/molbev/msv337;
RA Nagy L.G., Riley R., Tritt A., Adam C., Daum C., Floudas D., Sun H.,
RA Yadav J.S., Pangilinan J., Larsson K.H., Matsuura K., Barry K., Labutti K.,
RA Kuo R., Ohm R.A., Bhattacharya S.S., Shirouzu T., Yoshinaga Y.,
RA Martin F.M., Grigoriev I.V., Hibbett D.S.;
RT "Comparative Genomics of Early-Diverging Mushroom-Forming Fungi Provides
RT Insights into the Origins of Lignocellulose Decay Capabilities.";
RL Mol. Biol. Evol. 33:959-970(2016).
CC -!- FUNCTION: Catalyzes the intermembrane transfer of phosphatidylglycerol
CC and phosphatidylinositol. {ECO:0000256|ARBA:ARBA00002053}.
CC -!- SUBUNIT: Monomer. {ECO:0000256|ARBA:ARBA00011245}.
CC -!- SIMILARITY: Belongs to the NPC2 family.
CC {ECO:0000256|ARBA:ARBA00006370}.
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DR EMBL; KV428006; KZT43803.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A166IJG2; -.
DR Proteomes; UP000076798; Unassembled WGS sequence.
DR GO; GO:0032934; F:sterol binding; IEA:InterPro.
DR GO; GO:0032366; P:intracellular sterol transport; IEA:InterPro.
DR CDD; cd00917; PG-PI_TP; 1.
DR Gene3D; 2.70.220.10; Ganglioside GM2 activator; 2.
DR InterPro; IPR036846; GM2-AP_sf.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR003172; ML_dom.
DR InterPro; IPR033917; ML_PG-PI_TP.
DR InterPro; IPR039670; NPC2-like.
DR PANTHER; PTHR11306; NIEMANN PICK TYPE C2 PROTEIN NPC2-RELATED; 1.
DR PANTHER; PTHR11306:SF0; PHOSPHATIDYLGLYCEROL_PHOSPHATIDYLINOSITOL TRANSFER PROTEIN; 1.
DR Pfam; PF02221; E1_DerP2_DerF2; 1.
DR SMART; SM00737; ML; 1.
DR SUPFAM; SSF81296; E set domains; 1.
PE 3: Inferred from homology;
KW Lipid transport {ECO:0000256|ARBA:ARBA00023055};
KW Reference proteome {ECO:0000313|Proteomes:UP000076798};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transport {ECO:0000256|ARBA:ARBA00023055}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..171
FT /note="Phosphatidylglycerol/phosphatidylinositol transfer
FT protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5007875263"
FT DOMAIN 45..167
FT /note="MD-2-related lipid-recognition"
FT /evidence="ECO:0000259|SMART:SM00737"
SQ SEQUENCE 171 AA; 18667 MW; D3C8C2EC4AC70A91 CRC64;
MLRLQILLAV LLALLQLTVA RVPIFQQNQE IMGTPAVAGR DKWSWTDCGL PTDAAHIDTI
AVSPDPPRPG QNMTVTVTGT VKETIEDGSE ADVAVKLGLL KLLTRTFDLC EEARENDAEV
QCPIEAGYYE VSQTVALPKE IPPAVFSVDL SAYTAEGDDL LCLKLKIDFR K
//
