ID   A0A166IM05_9AGAM        Unreviewed;       744 AA.
AC   A0A166IM05;
DT   06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT   06-JUL-2016, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=Polynucleotide 5'-hydroxyl-kinase GRC3 {ECO:0000256|ARBA:ARBA00019824};
DE   AltName: Full=Polynucleotide 5'-hydroxyl-kinase grc3 {ECO:0000256|ARBA:ARBA00018706};
GN   ORFNames=PENSPDRAFT_602671 {ECO:0000313|EMBL:KZV73603.1};
OS   Peniophora sp. CONT.
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Russulales; Peniophoraceae; Peniophora.
OX   NCBI_TaxID=1314672 {ECO:0000313|EMBL:KZV73603.1, ECO:0000313|Proteomes:UP000077086};
RN   [1] {ECO:0000313|EMBL:KZV73603.1, ECO:0000313|Proteomes:UP000077086}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CONT {ECO:0000313|EMBL:KZV73603.1,
RC   ECO:0000313|Proteomes:UP000077086};
RX   PubMed=26659563; DOI=10.1093/molbev/msv337;
RA   Nagy L.G., Riley R., Tritt A., Adam C., Daum C., Floudas D., Sun H.,
RA   Yadav J.S., Pangilinan J., Larsson K.H., Matsuura K., Barry K., Labutti K.,
RA   Kuo R., Ohm R.A., Bhattacharya S.S., Shirouzu T., Yoshinaga Y.,
RA   Martin F.M., Grigoriev I.V., Hibbett D.S.;
RT   "Comparative Genomics of Early-Diverging Mushroom-Forming Fungi Provides
RT   Insights into the Origins of Lignocellulose Decay Capabilities.";
RL   Mol. Biol. Evol. 33:959-970(2016).
CC   -!- SIMILARITY: Belongs to the Clp1 family. NOL9/GRC3 subfamily.
CC       {ECO:0000256|ARBA:ARBA00011003}.
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DR   EMBL; KV424488; KZV73603.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A166IM05; -.
DR   STRING; 1314672.A0A166IM05; -.
DR   InParanoid; A0A166IM05; -.
DR   OrthoDB; 5480745at2759; -.
DR   Proteomes; UP000077086; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0051731; F:polynucleotide 5'-hydroxyl-kinase activity; IEA:InterPro.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR045116; Clp1/Grc3.
DR   InterPro; IPR032319; CLP1_P.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR12755; CLEAVAGE/POLYADENYLATION FACTOR IA SUBUNIT CLP1P; 1.
DR   PANTHER; PTHR12755:SF3; POLYNUCLEOTIDE 5'-HYDROXYL-KINASE NOL9; 1.
DR   Pfam; PF16575; CLP1_P; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Kinase {ECO:0000256|ARBA:ARBA00022777};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000077086};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          365..523
FT                   /note="Polyribonucleotide 5'-hydroxyl-kinase Clp1 P-loop"
FT                   /evidence="ECO:0000259|Pfam:PF16575"
FT   REGION          1..163
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        16..51
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        64..81
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        82..101
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   744 AA;  79895 MW;  9C3AB663BA8731CC CRC64;
     MLSAVAARKL KQGQQDPAAP SPTTVQPAAP IPSILNGSPS KQHASSSKKT NNKPSSKRKP
     SGHPAPKSAS KKPRRSRSKG KDKATPRYFA EPVHADASDD DAVISVDEDE EDEREGMLVG
     PNTDPLPSST KRAYSPSRPV EEDSSDDDVP APSAPLRLKS VQRQPAPVTV STFEPSLDQN
     MFVLTADERS ILALGDENAI VLLLSAQETF SFIGTSRLHV LRGSVVMHGT TLRASNISHP
     VFAPRSSPVP SLQAITTPDG SSEQASVALP SRIKRLSKGA AAIVALREMF TGVEGLGHVV
     RTFDGVFRPS LDDSVLELPL VGAAMCVRSS RDIQPFVMPS SWEDALQEVT SAEGSGAPPV
     YFVKGPKNSG KSTLARTMVN RLTARYRRVA YLDCDIGQSE FTPGGMVALT VVERPLFGPP
     FTHMTVPYQA HYLGSSSPRS SPSHYLSCIE ALLHAYRIDL QYGAVVDVDD DAEDGRIPES
     IPLVVNTMGW AKGLGADLTL KIEHLAAPSA VFSFYPDPPP EEYDGPPLHL LDPIAPPTHV
     PRYTAADHRA LALLSYFHSI FPSSDRTVAQ RTAEKWDTRL PLCATPPYEL DMRATIQNVV
     LAGAGMEDVV PTEILRVLNG ALVGLVKSDD DGAPYTSEGW ALPYSQAAPP PDPTASHCTA
     LAVIRAVSPD GSKIHLLTPL PSSANTFVKG ELEIPVWGML DFRDGGAGEE TGLPFLRWGK
     AGADGAIGGE RRRIRRNLMR KGQM
//