ID A0A166T4G6_9RHOB Unreviewed; 430 AA.
AC A0A166T4G6;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=3-hydroxyacyl-CoA dehydrogenase {ECO:0000313|EMBL:KZY02686.1};
GN ORFNames=A3721_04205 {ECO:0000313|EMBL:KZY02686.1};
OS Sulfitobacter sp. HI0023.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Sulfitobacter.
OX NCBI_TaxID=1822225 {ECO:0000313|EMBL:KZY02686.1, ECO:0000313|Proteomes:UP000077323};
RN [1] {ECO:0000313|EMBL:KZY02686.1, ECO:0000313|Proteomes:UP000077323}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HI0023 {ECO:0000313|EMBL:KZY02686.1,
RC ECO:0000313|Proteomes:UP000077323};
RA Sosa O.A.;
RT "Microbial cycling of marine high molecular weight dissolved organic
RT matter.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KZY02686.1}.
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DR EMBL; LWEQ01000179; KZY02686.1; -; Genomic_DNA.
DR RefSeq; WP_067920680.1; NZ_LWEQ01000179.1.
DR AlphaFoldDB; A0A166T4G6; -.
DR OrthoDB; 9771883at2; -.
DR Proteomes; UP000077323; Unassembled WGS sequence.
DR GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0044248; P:cellular catabolic process; IEA:UniProt.
DR GO; GO:0006631; P:fatty acid metabolic process; IEA:InterPro.
DR GO; GO:1901575; P:organic substance catabolic process; IEA:UniProt.
DR Gene3D; 1.10.1040.50; -; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR006176; 3-OHacyl-CoA_DH_NAD-bd.
DR InterPro; IPR006108; 3HC_DH_C.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR23309; 3-HYDROXYACYL-COA DEHYROGENASE; 1.
DR PANTHER; PTHR23309:SF9; PEROXISOMAL BIFUNCTIONAL ENZYME; 1.
DR Pfam; PF00725; 3HCDH; 2.
DR Pfam; PF02737; 3HCDH_N; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 2.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000077323}.
FT DOMAIN 38..213
FT /note="3-hydroxyacyl-CoA dehydrogenase NAD binding"
FT /evidence="ECO:0000259|Pfam:PF02737"
FT DOMAIN 218..302
FT /note="3-hydroxyacyl-CoA dehydrogenase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00725"
FT DOMAIN 338..417
FT /note="3-hydroxyacyl-CoA dehydrogenase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00725"
SQ SEQUENCE 430 AA; 46958 MW; A45E47EEF683D24F CRC64;
MTRPSEAETG DYIAKAGKAA WEVPGLPEDT PRREIRSVGI IGAGTMGGGI AMNFATAGIP
VKIVETTQEA LDRGLKVVRG NYQRSADKGR FPQDEVEARM DRFDGRLDIA DLADCDLVIE
AVFEDMELKR KIFTRLDEVM KQGAILATNT SALDIDEIAA MTKRPEDVIG LHFFSPANVM
KLLEIVRAAH TADDVVATCM DLAAKINKIA VLVGVCPGFV GNRILFARQK QANKLVYQGV
MPWDVDAALN DFGFKMGPFQ MSDLAGLDIG WSKGANTDNP IRDALCEMDR RGQKTGAGFY
DYDENRRPIP SDVTAGVVKD ITGAEPTSMS RDEIIEICIY PMINEAVKIL EENKAQRPSD
IDVVWLNGYG WPADKGGPMF YGDIVGAQAV LDRMEKLGAE DPEFAPADTL RELARTGGKF
TEIDKGGLKT
//
