ID   A0A166X798_9PEZI        Unreviewed;       758 AA.
AC   A0A166X798;
DT   06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT   06-JUL-2016, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=DUF21 and CBS domain protein {ECO:0000313|EMBL:KZL76327.1};
GN   ORFNames=CT0861_12415 {ECO:0000313|EMBL:KZL76327.1};
OS   Colletotrichum tofieldiae.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Glomerellales; Glomerellaceae; Colletotrichum;
OC   Colletotrichum spaethianum species complex.
OX   NCBI_TaxID=708197 {ECO:0000313|EMBL:KZL76327.1, ECO:0000313|Proteomes:UP000076552};
RN   [1] {ECO:0000313|EMBL:KZL76327.1, ECO:0000313|Proteomes:UP000076552}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=0861 {ECO:0000313|EMBL:KZL76327.1,
RC   ECO:0000313|Proteomes:UP000076552};
RA   Hacquard S., Kracher B., Hiruma K., Weinman A., Muench P., Garrido Oter R.,
RA   Ver Loren van Themaat E., Dallerey J.-F., Damm U., Henrissat B.,
RA   Lespinet O., Thon M., Kemen E., McHardy A.C., Schulze-Lefert P.,
RA   O'Connell R.J.;
RT   "Survival trade-offs in plant roots during colonization by closely related
RT   pathogenic and mutualistic fungi.";
RL   Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KZL76327.1}.
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DR   EMBL; LFIV01000016; KZL76327.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A166X798; -.
DR   STRING; 708197.A0A166X798; -.
DR   OrthoDB; 248389at2759; -.
DR   Proteomes; UP000076552; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0010960; P:magnesium ion homeostasis; IEA:InterPro.
DR   CDD; cd04590; CBS_pair_CorC_HlyC_assoc; 1.
DR   Gene3D; 3.10.580.10; CBS-domain; 1.
DR   InterPro; IPR045095; ACDP.
DR   InterPro; IPR000644; CBS_dom.
DR   InterPro; IPR046342; CBS_dom_sf.
DR   InterPro; IPR002550; CNNM.
DR   InterPro; IPR044751; Ion_transp-like_CBS.
DR   PANTHER; PTHR12064; METAL TRANSPORTER CNNM; 1.
DR   PANTHER; PTHR12064:SF100; PROTEIN MAM3; 1.
DR   Pfam; PF01595; CNNM; 1.
DR   SUPFAM; SSF54631; CBS-domain pair; 1.
DR   PROSITE; PS51371; CBS; 1.
DR   PROSITE; PS51846; CNNM; 1.
PE   4: Predicted;
KW   CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW   ProRule:PRU01193}; Reference proteome {ECO:0000313|Proteomes:UP000076552};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW   ProRule:PRU01193};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, ECO:0000256|PROSITE-
KW   ProRule:PRU01193}.
FT   TRANSMEM        20..44
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        64..86
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        178..198
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          57..242
FT                   /note="CNNM transmembrane"
FT                   /evidence="ECO:0000259|PROSITE:PS51846"
FT   DOMAIN          322..388
FT                   /note="CBS"
FT                   /evidence="ECO:0000259|PROSITE:PS51371"
FT   REGION          404..462
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          522..758
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        447..462
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        546..562
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        608..629
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        637..654
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        670..718
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   758 AA;  80842 MW;  F3FBBD79DF2CCF77 CRC64;
     MATRGVVPTR RANNAGGFGL FRTAVLGLTK ALTLGVSSVA AAPIHAVNHP DNEPEAEGSS
     FWPLMGASIA LVLLGGAFAG LTIALMGQDS IYLQVLAGDP DESQSKNAKR VYNLLKKGKH
     WVLVTLLLSN VIVNESLPVV LDRCLGGGVE AVVGSTVLIV IFGEVVPQSV CVRYGLQIGG
     YMSKPVLLLM WLMAPIAWPT AKLLDWALGE DHGTVYKKSG LKTLVTLHKS LGEVGERLNQ
     DEVTIISAVL DLKEKPVENV MTPMDDVFIM AEDTVLDEKT MDRILSEGYS RIPIHATGKP
     TDFVGMLLVK ILITYDPEDC LQVKDFPLAT LPETRPETSC LDIVNFFQEG KSHMVLVSEY
     PGADYGAIGV VTLEDVIEEL IGEEIIDESD VYIDVHKAIR RMTPAPKART PKKTGQPSPR
     PIPENGDLIE FGDEPHPPYE RNGSISALSD APENLSSSAP RTTFLMRRSS AGPDGRMTSS
     AVPIKATFDE AKQHLKHLGP SNRASNPKNT KSTTVKIKPV QTGAPLSQVH SPSPALRPAS
     AAGEVSEQRL DEETDEHTPL MRPKLTGKGG VHAIRKSYGG AGKSEAQVRL SSGGHDAEDD
     KSTDEVNVPA TVPENGSPEA TQSGSPEAPR TDLTIIVSPG RVSSATSVTS IAEEGSATPK
     RRPLVRSGSI SENVVETSSG VRKIIIQAAS SDSDEAGSKG SSGHRSRTAS QANTQTSGRD
     SEGEEHDGDG ASSTAPSTNN SQQASKKKNR RKKRKNKS
//