ID A0A167AN60_9PEZI Unreviewed; 594 AA.
AC A0A167AN60;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Probable lysosomal cobalamin transporter {ECO:0000256|ARBA:ARBA00017088};
GN ORFNames=CI238_10023 {ECO:0000313|EMBL:KZL80326.1};
OS Colletotrichum incanum.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Glomerellales; Glomerellaceae; Colletotrichum;
OC Colletotrichum spaethianum species complex.
OX NCBI_TaxID=1573173 {ECO:0000313|EMBL:KZL80326.1, ECO:0000313|Proteomes:UP000076584};
RN [1] {ECO:0000313|EMBL:KZL80326.1, ECO:0000313|Proteomes:UP000076584}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MAFF 238704 {ECO:0000313|EMBL:KZL80326.1,
RC ECO:0000313|Proteomes:UP000076584};
RA Hacquard S., Kracher B., Hiruma K., Weinman A., Muench P., Garrido Oter R.,
RA Ver Loren van Themaat E., Dallerey J.-F., Damm U., Henrissat B.,
RA Lespinet O., Thon M., Kemen E., McHardy A.C., Schulze-Lefert P.,
RA O'Connell R.J.;
RT "Survival trade-offs in plant roots during colonization by closely related
RT pathogenic and mutualistic fungi.";
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Probable lysosomal cobalamin transporter. Required to export
CC cobalamin from lysosomes allowing its conversion to cofactors.
CC {ECO:0000256|ARBA:ARBA00025515}.
CC -!- SUBCELLULAR LOCATION: Lysosome membrane
CC {ECO:0000256|ARBA:ARBA00004155}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004155}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the LIMR family. LMBRD1 subfamily.
CC {ECO:0000256|ARBA:ARBA00009901}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KZL80326.1}.
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DR EMBL; LFIW01001914; KZL80326.1; -; Genomic_DNA.
DR STRING; 1573173.A0A167AN60; -.
DR OrthoDB; 8533at2759; -.
DR Proteomes; UP000076584; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0031419; F:cobalamin binding; IEA:UniProtKB-KW.
DR InterPro; IPR006876; LMBR1-like_membr_prot.
DR PANTHER; PTHR16130:SF2; LYSOSOMAL COBALAMIN TRANSPORT ESCORT PROTEIN LMBD1; 1.
DR PANTHER; PTHR16130; LYSOSOMAL COBALAMIN TRANSPORTER-RELATED; 1.
DR Pfam; PF04791; LMBR1; 1.
PE 3: Inferred from homology;
KW Cobalamin {ECO:0000256|ARBA:ARBA00022628};
KW Cobalt {ECO:0000256|ARBA:ARBA00023285};
KW Lysosome {ECO:0000256|ARBA:ARBA00023228};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000076584};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
SQ SEQUENCE 594 AA; 65802 MW; 29F1506601D1203F CRC64;
MANAGLLQTS LIWVAYAVAV VLCLLAAIIT TFTWQTPRER SAIVSIVAIV SLTSLLATVL
LLPVDIALIS STTHASLGVK KDWATEQRVH DILQTLRIVY YSLYSFDALL CLLIIPFAYF
WHEEYDEIEV EEGRSFGSRL ISALKYTLVF VVLVVILFLV GFFVPAAGDH NGANWDLDYF
KRILVQNNGQ KALSFALGLL VTLGVLLYVI YTAAGLALLP MSFIKSAPSI SAPQLTESTA
SALEQNRERQ RQLEMRNAGR PEGMPSKDRR ELEALVREER TLTRRERLAA EASGEGRSTI
YKVWLKICAV FRPIKLLGGI LLLLLSVLIW VSMLITGIDK AKNSFCKGKC GYILGHINIF
QPINWIFTQS AKAFPVDYIL MALLVLFFFS SSISGIATVG IRFLWVRIFQ IRKGRTAPQA
LLVATVMLAL IILAINYAIA NMVAPQYSIY GTQTFCTAPH HAGETPNCRG RPDYLVQCSE
ALDPDALKVC TPSIMAEFLN RIAITWPFFG SLDFWAQFVF LGIFLIVFVT GLFRAPKLNV
SELDEDAEED EEEGLLASTG RRFGATWQDI TGRTKSKSTY GTQEGNNGGG SSEA
//
