ID   A0A167EYM8_9HYPO        Unreviewed;       860 AA.
AC   A0A167EYM8;
DT   06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT   06-JUL-2016, sequence version 1.
DT   24-JAN-2024, entry version 24.
DE   RecName: Full=Anaphase-promoting complex subunit 2 {ECO:0000256|ARBA:ARBA00016068};
GN   ORFNames=BBO_04060 {ECO:0000313|EMBL:OAA44577.1};
OS   Beauveria brongniartii RCEF 3172.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Cordycipitaceae; Beauveria;
OC   Beauveria brongniartii.
OX   NCBI_TaxID=1081107 {ECO:0000313|EMBL:OAA44577.1, ECO:0000313|Proteomes:UP000076863};
RN   [1] {ECO:0000313|EMBL:OAA44577.1, ECO:0000313|Proteomes:UP000076863}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RCEF 3172 {ECO:0000313|EMBL:OAA44577.1,
RC   ECO:0000313|Proteomes:UP000076863};
RX   PubMed=27071652; DOI=10.1093/gbe/evw082;
RA   Shang Y., Xiao G., Zheng P., Cen K., Zhan S., Wang C.;
RT   "Divergent and convergent evolution of fungal pathogenicity.";
RL   Genome Biol. Evol. 8:1374-1387(2016).
CC   -!- SIMILARITY: Belongs to the cullin family. {ECO:0000256|PROSITE-
CC       ProRule:PRU00330, ECO:0000256|RuleBase:RU003829}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OAA44577.1}.
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DR   EMBL; AZHA01000010; OAA44577.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A167EYM8; -.
DR   OrthoDB; 2786196at2759; -.
DR   Proteomes; UP000076863; Unassembled WGS sequence.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR   Gene3D; 1.20.1310.10; Cullin Repeats; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR044554; APC2-like.
DR   InterPro; IPR014786; APC2_C.
DR   InterPro; IPR016158; Cullin_homology.
DR   InterPro; IPR036317; Cullin_homology_sf.
DR   InterPro; IPR001373; Cullin_N.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR45957; ANAPHASE-PROMOTING COMPLEX SUBUNIT 2; 1.
DR   PANTHER; PTHR45957:SF1; ANAPHASE-PROMOTING COMPLEX SUBUNIT 2; 1.
DR   Pfam; PF08672; ANAPC2; 1.
DR   Pfam; PF00888; Cullin; 1.
DR   SMART; SM01013; APC2; 1.
DR   SMART; SM00182; CULLIN; 1.
DR   SUPFAM; SSF75632; Cullin homology domain; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50069; CULLIN_2; 1.
PE   3: Inferred from homology;
KW   Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW   Cell division {ECO:0000256|ARBA:ARBA00022618};
KW   Mitosis {ECO:0000256|ARBA:ARBA00022776};
KW   Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT   DOMAIN          530..733
FT                   /note="Cullin family profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50069"
FT   REGION          24..62
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          757..786
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   860 AA;  95796 MW;  9310EA9BC9CA3864 CRC64;
     MSALTVRARR QKIFKAVFQT DLSQPTPLLS STEPGEPFGG PPAATVKASP RRRRSAGNDG
     GISDQVKWDR AWHLVTSRIQ LPSSVAIEDS FGTLPPQSQD SDSDFYEALP IVLDPAVNVP
     CAAHTEDILL WHARQVRQHF VHHVLPLLAA CASLADTSQV VSSTVNTLAA AHRQYLNGLL
     LVVRGISNEA ASETATSTFR RDLHAVIGNS WTQGLINALN PALKRLLRTV LNIGQRFDGR
     HTPEEPNASS AREELLSLLE SLQRVGLAGD KFQVLFAELM DNCMHEFIQT AYDGVWDSAE
     VKDSSTGSVM PGCMAHLCDW VENHYGRLAV EVFSRLGGQV KWADVEQWRD IAIGRLATLR
     IHELFDIVLH WPETKGGLDD LGYSVTTPQR RLELTDAFSA ALQQRLLHPG RSTLEILQTY
     ISMIRTFHAL DHSKVLLDRV VHALQLYLCQ RDDAIRIVVT GLLANPKGDD DIEAKTKLVE
     LAVVINEASQ QQRTAIDEED LDWDDMNWVP DPVDAGVNYK RPKNEDVVGT LISALGSQDI
     FIKEFQHIIA ERLLSKQHGF QQEIKVLGLL KKRFGQHALQ NCDVMVKDIQ DSRRLDTVLR
     RNIRSNQDPE SPALSYHSKI LSRLFWPSLT KETFKVPAPV AEIQSQYEAG FEQLKSSRKL
     GWLDNLGTAT VKLELDDRTV EVDCKTCEAA VIFEFQGDGA QSDTGAQQRT FEELWQSLMM
     DEDALELALR FWVAKKVLKD IGSQTYVVVE RLTPDEAAGD TRDDASVEEG PEAPGSISPK
     KAKALDPREA ERRTIYWQFI LGMLTNSAPA MPLGQIAMMM KMLIADGCDW SNEELQGFLD
     GKIAAGELEL AGGKYRLPKK
//