ID   A0A167INF4_METRR        Unreviewed;       789 AA.
AC   A0A167INF4;
DT   06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT   06-JUL-2016, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   SubName: Full=Heat shock protein 78 {ECO:0000313|EMBL:OAA49257.1};
GN   ORFNames=NOR_01180 {ECO:0000313|EMBL:OAA49257.1};
OS   Metarhizium rileyi (strain RCEF 4871) (Nomuraea rileyi).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Clavicipitaceae; Metarhizium.
OX   NCBI_TaxID=1081105 {ECO:0000313|EMBL:OAA49257.1, ECO:0000313|Proteomes:UP000243498};
RN   [1] {ECO:0000313|EMBL:OAA49257.1, ECO:0000313|Proteomes:UP000243498}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RCEF 4871 {ECO:0000313|EMBL:OAA49257.1,
RC   ECO:0000313|Proteomes:UP000243498};
RX   PubMed=27071652; DOI=10.1093/gbe/evw082;
RA   Shang Y., Xiao G., Zheng P., Cen K., Zhan S., Wang C.;
RT   "Divergent and convergent evolution of fungal pathogenicity.";
RL   Genome Biol. Evol. 8:1374-1387(2016).
CC   -!- SIMILARITY: Belongs to the ClpA/ClpB family.
CC       {ECO:0000256|ARBA:ARBA00008675, ECO:0000256|RuleBase:RU004432}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OAA49257.1}.
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DR   EMBL; AZHC01000003; OAA49257.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A167INF4; -.
DR   STRING; 1081105.A0A167INF4; -.
DR   OMA; SKMMQGE; -.
DR   OrthoDB; 35211at2759; -.
DR   Proteomes; UP000243498; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   CDD; cd00009; AAA; 1.
DR   CDD; cd19499; RecA-like_ClpB_Hsp104-like; 1.
DR   Gene3D; 1.10.8.60; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003959; ATPase_AAA_core.
DR   InterPro; IPR019489; Clp_ATPase_C.
DR   InterPro; IPR001270; ClpA/B.
DR   InterPro; IPR018368; ClpA/B_CS1.
DR   InterPro; IPR028299; ClpA/B_CS2.
DR   InterPro; IPR041546; ClpA/ClpB_AAA_lid.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR11638; ATP-DEPENDENT CLP PROTEASE; 1.
DR   PANTHER; PTHR11638:SF18; HEAT SHOCK PROTEIN 78, MITOCHONDRIAL; 1.
DR   Pfam; PF00004; AAA; 1.
DR   Pfam; PF07724; AAA_2; 1.
DR   Pfam; PF17871; AAA_lid_9; 1.
DR   Pfam; PF10431; ClpB_D2-small; 1.
DR   PRINTS; PR00300; CLPPROTEASEA.
DR   SMART; SM00382; AAA; 2.
DR   SMART; SM01086; ClpB_D2-small; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR   PROSITE; PS00870; CLPAB_1; 1.
DR   PROSITE; PS00871; CLPAB_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU004432};
KW   Chaperone {ECO:0000256|RuleBase:RU004432};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW   ECO:0000256|RuleBase:RU004432};
KW   Reference proteome {ECO:0000313|Proteomes:UP000243498};
KW   Stress response {ECO:0000313|EMBL:OAA49257.1}.
FT   DOMAIN          112..256
FT                   /note="AAA+ ATPase"
FT                   /evidence="ECO:0000259|SMART:SM00382"
FT   DOMAIN          512..652
FT                   /note="AAA+ ATPase"
FT                   /evidence="ECO:0000259|SMART:SM00382"
FT   DOMAIN          690..781
FT                   /note="Clp ATPase C-terminal"
FT                   /evidence="ECO:0000259|SMART:SM01086"
FT   COILED          325..405
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   789 AA;  87683 MW;  FD456EBED0F38C67 CRC64;
     MQARRQLIAS AQQIAGATTR SSRPALRLAA IRSARASPLR LLPTIATRCY ANGRPHPPGG
     THRMNMGGEE EKSALEQFGI DLTSRAKDGK LDPVIGRDAE IQRTIQILSR RTKNNPVLIG
     NAGTGKTAIL EGLALRIVRG DVPESIKNKR VISLDLGSLI AGAKFRGDFE ERLKKVLDEV
     QKAEGQVILF IDELHTLLGL GKAEGSIDAS NLLKPALARG ELQCCGATTL TEYRQIEKDV
     ALARRFQPII VSEPSVEDTV SILRGIKDKY EVHHGVRITD GALVAAATLS NRYVTDRFLP
     DKAIDLMDEA ASHLKLQHES KPEDIMRLDH KIMTIQIELE SLRKEKDVAS QERREKLEKD
     LKGYQDEIAQ LNARWEKERS EIESVKRVQE DLEKARFDLE QAQREGNFAR ASELRFGVIP
     DLEQKLPSNE ESQQTPPEET LIHDSVTSDD IANVVSRITG IPVSKLTSGH IEKLVHMEDT
     LREAVKGQDD AIKAVSDAVR LQRAGLSGEN KPLASFFFLG PTGVGKTELC KKLAGFLFST
     ESAVVRFDMS EFQEKHTISR LIGAPSGYVG YEDAGQLTEA VRRKPYAVLL FDEFEKAHRD
     ISALLLQVLD EGYLTDAQGH KVDFKNTIIV LTSNLGADIL VGQNQLHPYK ESPDGEIDPS
     VRKAVMDVVA QAYPPEFLNR IDSFIVFKRL AQSAIRQIVD IRLKELQHRL DDKRIKLTVP
     DAVKDWLAER GYEPKFGARP LNRLITNEIG NGLADKIIRG QLKMGQAAEV RIRQDNTGLE
     VLNASETVV
//