ID A0A167M8B5_PHYB8 Unreviewed; 1583 AA.
AC A0A167M8B5;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=P-loop containing nucleoside triphosphate hydrolase protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=PHYBLDRAFT_170003 {ECO:0000313|EMBL:OAD72104.1};
OS Phycomyces blakesleeanus (strain ATCC 8743b / DSM 1359 / FGSC 10004 / NBRC
OS 33097 / NRRL 1555).
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Phycomycetaceae; Phycomyces.
OX NCBI_TaxID=763407 {ECO:0000313|EMBL:OAD72104.1, ECO:0000313|Proteomes:UP000077315};
RN [1] {ECO:0000313|Proteomes:UP000077315}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 1555(-) {ECO:0000313|Proteomes:UP000077315};
RG DOE Joint Genome Institute;
RA Corrochano L.M., Kuo A., Marcet-Houben M., Polaino S., Salamov A.,
RA Villalobos J.M., Alvarez M.I., Avalos J., Benito E.P., Benoit I.,
RA Burger G., Camino L.P., Canovas D., Cerda-Olmedo E., Cheng J.-F.,
RA Dominguez A., Elias M., Eslava A.P., Glaser F., Grimwood J., Gutierrez G.,
RA Heitman J., Henrissat B., Iturriaga E.A., Lang B.F., Lavin J.L., Lee S.,
RA Li W., Lindquist E., Lopez-Garcia S., Luque E.M., Marcos A.T., Martin J.,
RA McCluskey K., Medina H.R., Miralles-Duran A., Miyazaki A., Munoz-Torres E.,
RA Oguiza J.A., Ohm R., Olmedo M., Orejas M., Ortiz-Castellanos L.,
RA Pisabarro A.G., Rodriguez-Romero J., Ruiz-Herrera J., Ruiz-Vazquez R.,
RA Sanz C., Schackwitz W., Schmutz J., Shahriari M., Shelest E.,
RA Silva-Franco F., Soanes D., Syed K., Tagua V.G., Talbot N.J., Thon M.,
RA De vries R.P., Wiebenga A., Yadav J.S., Braun E.L., Baker S., Garre V.,
RA Horwitz B., Torres-Martinez S., Idnurm A., Herrera-Estrella A.,
RA Gabaldon T., Grigoriev I.V.;
RT "Expansion of signal transduction pathways in fungi by whole-genome
RT duplication.";
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; KV440984; OAD72104.1; -; Genomic_DNA.
DR RefSeq; XP_018290144.1; XM_018436227.1.
DR STRING; 763407.A0A167M8B5; -.
DR GeneID; 28997133; -.
DR VEuPathDB; FungiDB:PHYBL_170003; -.
DR InParanoid; A0A167M8B5; -.
DR OrthoDB; 1354018at2759; -.
DR Proteomes; UP000077315; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd18596; ABC_6TM_VMR1_D1_like; 1.
DR CDD; cd18604; ABC_6TM_VMR1_D2_like; 1.
DR Gene3D; 1.20.1560.10; ABC transporter type 1, transmembrane domain; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011527; ABC1_TM_dom.
DR InterPro; IPR036640; ABC1_TM_sf.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR24223:SF353; ABC TRANSPORTER ATP-BINDING PROTEIN_PERMEASE VMR1-RELATED; 1.
DR PANTHER; PTHR24223; ATP-BINDING CASSETTE SUB-FAMILY C; 1.
DR Pfam; PF00664; ABC_membrane; 2.
DR Pfam; PF00005; ABC_tran; 2.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF90123; ABC transporter transmembrane region; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS50929; ABC_TM1F; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000077315};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 31..50
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 85..106
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 171..194
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 214..232
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 334..352
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 375..400
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 489..507
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 572..603
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1048..1068
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1119..1140
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1147..1168
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1180..1200
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1231..1253
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1259..1280
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 340..619
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT DOMAIN 682..930
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 1040..1288
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT DOMAIN 1325..1572
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 1583 AA; 178883 MW; 174CC2B3A17939FF CRC64;
MNFALPFCGC AEPPEIGSLS LEFDSCTRET LLDAALPLAF LIVSLGVNSL RRYRTWRTGA
LRLTGDADTL RLPTTKQAAL LRQSLILLVL VLLEISTWAF IFAWRLESAI LDRDNPKHAT
ELTSALTERC GTPPYQVLDP ILALIPRIYI LILVIRSFTT PADPVAPSKF TLYNPHFLTF
YSFALISAIV RIFAHFGTLL NSRDGVPSGV EKGFSLVDCF ICLAIWLVSA TTPSELDQGE
LLDFDDDDDG VMVLNDGRVV RNGRILSFEA TASPLSFMTF GWINSLLHKA YKKPLTADQL
WALPLRQRAQ ENFRQFKQTI NSSLVRRIYE ANKTIILVQF VTAIAAVFFH YANPFFLRKL
LNYIQDSKNQ PSDIGYLYCL AIFVCSIIST LVASQTLLWG RRWHVSMTNM LNSEIYEHTL
QLNHPKETTV NKSESEEDAE NALPNKLASL MSRDTERLAE LASYLHIFYT CPLEIGVGVI
FLYQVLGNSF LAGLVVMAVT LPSTHFISQR LIHVQKQLEE AKTWRTRLLK ELFEGIKTTK
FLAWEHKWEH VIAAARDDEL VKLIKLYTQN TILGLIWFAT PVLVTTISFA CTAFVSIVLF
GMLREPLNVM PQAFMAYNDA KVSLEHINSF LNSGEKRYSD SDSSTPYEAM NYSYTEHVQT
GFDEGSFQWL PKSEPSVRRP YVRDKATLSP NSSDGHLSSF RLTVPEIDFP VGSISVITGP
RKSGKSSMIS ALLGEMKGVS GSSHIPSRFL TMRTNLIRDQ KYRALYVFRV AYVAQIPWIE
SGTIRENILF SDPWDDSRYR AVLYQCDLLR DLSLLENGDL TQIGERGMAL TESQKHKISL
ARAVYSRAKT VLIDDLFALL ETPTVNFLFD KCISGDLMQG RTVIITATEL GQWACNAQLL
VCLDSGNVSQ IERECDAIST WVFTHQARRD SSTAVVASDD RIEALFETDN VYTDDDFFDE
ASVLRESIAA PEDITIENTK ARKYAYATYF SACGGWQFWM SAIMFTVLAR VSSISESYWL
KEDVPIFIPT PTQPEKEIPD ENVINHYVII YLGLSMVTVA FNFSRTVVQY RGSLQASNRI
FLRLLQAVCH APLQFFDNTL QSDIMNRFSK DMETVDSSIG WHVNFLLQTL FGIIGVVIAI
GFILPEVYIV SFFAALLYLY IGMIYIRASG ELKKLNTDTR PAIVCLYADT LAGLSTIRAY
REQRGMMRKM FQRLDENMRP FYTLWTTNRW LFVRVEVLGA LISLFISVLL IYKRDTVDAG
SAGIALTFAT SLLEYVYWLM RQSTTVDMHF EAVERINEYL DMPQEPPGVV EGSRPPAAWP
ATAAINVRDL MVSYGGEEDP ILRHVSFNIL SGEKVALVGR AGAEKNVLVS CIFRFVDPLR
GSIKIDGVNI AWIGVKDLRS RITFIAKDGW LLSGTVRSNL DPFGEYDDYE LWQALYRVHL
AVSPISEEDV QNYVHSATTS TIYDLDMDLG KDGMALSVGN RQLLCVARAL LRDCTRLVVL
EEAQLTLETQ EKMQRVIEEE FEDSTLLVIP YSLQSVLRYD RAMVFDQGDL VEYDNPADLL
KREDGLLHSL FERAGILEAH ITE
//
