ID A0A167MGT5_PHYB8 Unreviewed; 1400 AA.
AC A0A167MGT5;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=Kinesin motor domain-containing protein {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
GN ORFNames=PHYBLDRAFT_95995 {ECO:0000313|EMBL:OAD72799.1};
OS Phycomyces blakesleeanus (strain ATCC 8743b / DSM 1359 / FGSC 10004 / NBRC
OS 33097 / NRRL 1555).
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Phycomycetaceae; Phycomyces.
OX NCBI_TaxID=763407 {ECO:0000313|EMBL:OAD72799.1, ECO:0000313|Proteomes:UP000077315};
RN [1] {ECO:0000313|Proteomes:UP000077315}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 1555(-) {ECO:0000313|Proteomes:UP000077315};
RG DOE Joint Genome Institute;
RA Corrochano L.M., Kuo A., Marcet-Houben M., Polaino S., Salamov A.,
RA Villalobos J.M., Alvarez M.I., Avalos J., Benito E.P., Benoit I.,
RA Burger G., Camino L.P., Canovas D., Cerda-Olmedo E., Cheng J.-F.,
RA Dominguez A., Elias M., Eslava A.P., Glaser F., Grimwood J., Gutierrez G.,
RA Heitman J., Henrissat B., Iturriaga E.A., Lang B.F., Lavin J.L., Lee S.,
RA Li W., Lindquist E., Lopez-Garcia S., Luque E.M., Marcos A.T., Martin J.,
RA McCluskey K., Medina H.R., Miralles-Duran A., Miyazaki A., Munoz-Torres E.,
RA Oguiza J.A., Ohm R., Olmedo M., Orejas M., Ortiz-Castellanos L.,
RA Pisabarro A.G., Rodriguez-Romero J., Ruiz-Herrera J., Ruiz-Vazquez R.,
RA Sanz C., Schackwitz W., Schmutz J., Shahriari M., Shelest E.,
RA Silva-Franco F., Soanes D., Syed K., Tagua V.G., Talbot N.J., Thon M.,
RA De vries R.P., Wiebenga A., Yadav J.S., Braun E.L., Baker S., Garre V.,
RA Horwitz B., Torres-Martinez S., Idnurm A., Herrera-Estrella A.,
RA Gabaldon T., Grigoriev I.V.;
RT "Expansion of signal transduction pathways in fungi by whole-genome
RT duplication.";
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Kinesin family. {ECO:0000256|PROSITE-ProRule:PRU00283}.
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DR EMBL; KV440982; OAD72799.1; -; Genomic_DNA.
DR RefSeq; XP_018290839.1; XM_018443941.1.
DR STRING; 763407.A0A167MGT5; -.
DR GeneID; 29004846; -.
DR VEuPathDB; FungiDB:PHYBL_95995; -.
DR InParanoid; A0A167MGT5; -.
DR OrthoDB; 1360435at2759; -.
DR Proteomes; UP000077315; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR CDD; cd22705; FHA_KIF1; 1.
DR CDD; cd01365; KISc_KIF1A_KIF1B; 1.
DR Gene3D; 2.60.200.20; -; 1.
DR Gene3D; 6.10.250.2520; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR InterPro; IPR000253; FHA_dom.
DR InterPro; IPR022164; Kinesin-like.
DR InterPro; IPR022140; Kinesin-like_KIF1-typ.
DR InterPro; IPR032405; Kinesin_assoc.
DR InterPro; IPR001752; Kinesin_motor_dom.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR PANTHER; PTHR47117:SF6; KINESIN-LIKE PROTEIN KIF1C ISOFORM X1; 1.
DR PANTHER; PTHR47117; STAR-RELATED LIPID TRANSFER PROTEIN 9; 1.
DR Pfam; PF12473; DUF3694; 1.
DR Pfam; PF00498; FHA; 1.
DR Pfam; PF12423; KIF1B; 1.
DR Pfam; PF00225; Kinesin; 1.
DR Pfam; PF16183; Kinesin_assoc; 2.
DR PRINTS; PR00380; KINESINHEAVY.
DR SMART; SM00240; FHA; 1.
DR SMART; SM00129; KISc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR PROSITE; PS50006; FHA_DOMAIN; 1.
DR PROSITE; PS50067; KINESIN_MOTOR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00283};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Motor protein {ECO:0000256|PROSITE-ProRule:PRU00283};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00283}; Reference proteome {ECO:0000313|Proteomes:UP000077315}.
FT DOMAIN 1..347
FT /note="Kinesin motor"
FT /evidence="ECO:0000259|PROSITE:PS50067"
FT DOMAIN 486..537
FT /note="FHA"
FT /evidence="ECO:0000259|PROSITE:PS50006"
FT REGION 566..591
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 657..694
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1121..1153
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 712..754
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 657..672
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 673..694
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 84..91
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00283"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:OAD72799.1"
FT NON_TER 1400
FT /evidence="ECO:0000313|EMBL:OAD72799.1"
SQ SEQUENCE 1400 AA; 157878 MW; 31B2EA38EAFF5BB1 CRC64;
HSEIARGATC LIRMDGDQTI ITKPSLAGQP KEEDTKAFTF DRSYWSADKN DPNFATQKTV
YNDLGRELLD HAFHGYNCCI FAYGQTGSGK SYSMMGYGKD KGIIPLTCSE LFDRIAESTT
DVLSFQVEVS YIEIYNEKVR DLLNPSNKSN LKVREHPSLG PYVEDLSRLA VKSFEDISHL
MNEGNKARTV AATNMNETSS RSHAVFTIFL TSARYDETAK LSTEKVARIR CVGKVIPILI
SSLVDLAGSE RADSTGATGM RLKEGANINK SLTTLGKVIS SLAEHGDTKK GKKSKEAFVP
YRDSVLTWLL KDSLGGNSKT AMIAAISPAD YEETLSTLRY ADQAKKIKNK AVVNEDPNAK
LIRELKEELQ ALRDTLMVYA PDEVDRIIVF TDASGHTQHL TREEVVDQLQ TAEKLLNQVN
RTWEEKLHST ETIHQDREKA LEELGVMVEK NNMGVYTPKS VPHLVNLNED PLMTECLVYQ
LKPGKTRVGR LDSTIPAEIR LSGPNIKDNH CFFEHNDGIV TLYPDEGSMT MVNGMRISDS
KRLHSGFRVI LGDYHVFRFN HPEEARRERD LQQRTTGSAA GLEPGSSQAL DMMCRPVSPS
ASSMREMAQS PEVVDWGFAR REAVLNYYSA ESNLGGLTDE DLEKLFDDVF RIRQSRKKRF
DGRSEADPDD ETLSRTSTSS SARPSHGQST VFGEDQSVSS LYLDTSTMTP NRDDLLRQVK
EEMQQQLDLQ KQAFEEKIKL LESVRAEMER MMDQQRYAYE SKIKRIAMHL PPGTSLQSPT
LPSVATEHET ILIYQTFLKW KSLRYVWMAE TIMSHAALLK EANVISKELN KNVIYQFFVL
HDHASVNPVS FWESGSELQP KGGGRLSRLS SETMPCVGVL VVDRKHEVTY VWSIEETQAR
LVRMRSLYDF TERPLENNES LTEQQDPFYE SPCPRYSLLG LAKVPIQNLA FQVPVESMVD
VVCRHSGHVL GHLRVLITPI ARSMARRAGN SQLTLPLSRQ SSRDSHQERF LHVGQQQVFE
VRIISLDGLS ESDATQVHAQ FRLSSFGNIE PNSPVDRIYA TDPISGFGTL PIDFHYAQTL
STTVTADMLE VITTKTLTVE IHGHLQSHFL RNMVQQSVER EELASPVATR PRMTLEPIPP
AHSRRPSDSP EDGQIREEVH DIVAWVKICE LEAEGEYEPV RVVYDSNNNN PKKSDGGGVF
SLRQGLQRRI SLSLMHASGR KLRWEAIEEM SIGNVRLLNS KGQEIAPAVH SDVPVYLFAE
QELVYHSNGT STLSAQGPWD SSLHNSLYLN RVSPDNQLVL LSLSWKVNCS SQCTVPIKFS
MDLAVMIQER DARLTAAVFS FLRSQRILRK MSAIFVLKLH PPMSRKLKDL WRLNTTHRYV
RGEELLGPWR PRGVSLVHEY
//
