ID A0A167NDI0_CALVF Unreviewed; 1411 AA.
AC A0A167NDI0;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Ras GEF {ECO:0000313|EMBL:KZO97598.1};
GN ORFNames=CALVIDRAFT_554479 {ECO:0000313|EMBL:KZO97598.1};
OS Calocera viscosa (strain TUFC12733).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Dacrymycetes;
OC Dacrymycetales; Dacrymycetaceae; Calocera.
OX NCBI_TaxID=1330018 {ECO:0000313|EMBL:KZO97598.1, ECO:0000313|Proteomes:UP000076738};
RN [1] {ECO:0000313|EMBL:KZO97598.1, ECO:0000313|Proteomes:UP000076738}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TUFC12733 {ECO:0000313|EMBL:KZO97598.1,
RC ECO:0000313|Proteomes:UP000076738};
RX PubMed=26659563; DOI=10.1093/molbev/msv337;
RA Nagy L.G., Riley R., Tritt A., Adam C., Daum C., Floudas D., Sun H.,
RA Yadav J.S., Pangilinan J., Larsson K.H., Matsuura K., Barry K., Labutti K.,
RA Kuo R., Ohm R.A., Bhattacharya S.S., Shirouzu T., Yoshinaga Y.,
RA Martin F.M., Grigoriev I.V., Hibbett D.S.;
RT "Comparative Genomics of Early-Diverging Mushroom-Forming Fungi Provides
RT Insights into the Origins of Lignocellulose Decay Capabilities.";
RL Mol. Biol. Evol. 33:959-970(2016).
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DR EMBL; KV417279; KZO97598.1; -; Genomic_DNA.
DR STRING; 1330018.A0A167NDI0; -.
DR OrthoDB; 5476208at2759; -.
DR Proteomes; UP000076738; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR CDD; cd06224; REM; 1.
DR Gene3D; 1.10.840.10; Ras guanine-nucleotide exchange factors catalytic domain; 1.
DR Gene3D; 1.20.870.10; Son of sevenless (SoS) protein Chain: S domain 1; 1.
DR InterPro; IPR008937; Ras-like_GEF.
DR InterPro; IPR000651; Ras-like_Gua-exchang_fac_N.
DR InterPro; IPR023578; Ras_GEF_dom_sf.
DR InterPro; IPR001895; RASGEF_cat_dom.
DR InterPro; IPR036964; RASGEF_cat_dom_sf.
DR PANTHER; PTHR23113; GUANINE NUCLEOTIDE EXCHANGE FACTOR; 1.
DR PANTHER; PTHR23113:SF364; GUANINE NUCLEOTIDE EXCHANGE FACTOR LTE1; 1.
DR Pfam; PF00617; RasGEF; 1.
DR Pfam; PF00618; RasGEF_N; 1.
DR SMART; SM00147; RasGEF; 1.
DR SUPFAM; SSF48366; Ras GEF; 1.
DR PROSITE; PS50009; RASGEF_CAT; 1.
DR PROSITE; PS50212; RASGEF_NTER; 1.
PE 4: Predicted;
KW Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658,
KW ECO:0000256|PROSITE-ProRule:PRU00168};
KW Reference proteome {ECO:0000313|Proteomes:UP000076738}.
FT DOMAIN 333..465
FT /note="N-terminal Ras-GEF"
FT /evidence="ECO:0000259|PROSITE:PS50212"
FT DOMAIN 1066..1407
FT /note="Ras-GEF"
FT /evidence="ECO:0000259|PROSITE:PS50009"
FT REGION 1..85
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 210..247
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 268..295
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 486..527
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 713..775
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 809..870
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..73
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 214..231
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 726..749
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 750..774
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 852..870
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1411 AA; 153937 MW; F912FF7D833FF9C1 CRC64;
MTSQHSATGL TPARQLSISI SASQAQRNTL TPPQTSPVRS SILPSVSPSK SHTTAPSHRT
TSSSTISPSS VGAPTPVTAP PMSAHVPGLG EDCFLDLMGM PTPPPSQRPR AGSVGIGGGR
NAGIPPAPQG VEAVARAPRA RLEDRWKAAE PPAEQEQEGE GPAEVAGSEE LDAMRLRALQ
DLADGTLTLE DRAHALRGSH SFDSVLTARV HSPGDAQSPD SDNTPTSVTP ANGPEPALPE
EGTRRPKYSF VSSYPTLAFD VLQTYDGSEL SSPRARAKEP APFEDGDAVN PLPPDDPRFI
LWSTPAPAST NPPRQSAYLN VPQPPPPSPA GPVRRTLLAC TLERWISQLT SSLDYDILLD
TLISYRPFFP PSALARLLIT RFMWTLQPPP TWLHPSDVQR QEVVRKIVRL RTMLVMRCWL
QVFFRVDFVH NKEARDVLIG WMNRMEREPE IQARDDVLKL VRRLKRIVRE CKDAYNRDVQ
TEFELGMKDS PIAPSAAPLP PARSNSNPIP PEEQNTEDID LSDLSPRPSV DYDRLAGRSA
AEEYAHLATY GKPNPSSKGR ESIRGIAEFT PAVVPPTQVP LLIPNSTAVA ASPPVSAVPP
VGLGLDLDDE PVVLGMGQVV PASPNHPGTG TRHAISRVMG KFKRAVAGKS SPVSAVGTAC
AGPDAAKMFL EDTPGLVSAA MMVGRTDSPP PVPMKEIQAQ QLEYIAPVVP EAEAAPQPPI
QPEEVYEAPK PEDETREEAN DDTIQITEAE SRTSEEFTPS LTPASPTSSE PVDSSGVWEK
RMVDHNEHEA DAHGSEAFTS LSIGTDRWQQ ESMTSLESGA DEHGHALGGH QPPHVISLDD
WDSDLDLDSS DEDDAPVQRQ PKRLPRRLPL RRELDERPVS IETVSSLGIR SYNDRDSVVS
ATFPVLHERE RELGPRNPLL EGPLAMWQLE LIGAYLESED EEGEEGGAAA ALAKLEGQID
QSRQAQRWKR AGEFIEEAAV IAQGMLDEKL VKDDASAERS SMGSTISARR TINVAPSTAS
PQNAVRPLTA TPARPHASSI GASALPAIPP PPSYLMTHVS LILVHSSTDL AEAFCLIDCE
MTLAIRFEEI LHLEWYGRVQ AEPDVLDWAS FIKNRAVVRY ELQQKQRKLR SQRNASGAAV
DPAAAGITEG AIRKLSDIAA IKARFNLMVH WVAHEILLTH PSRRVELVNK IIRIAYKAYK
MNSFATVVPI VAGLCSPEAS IAMRKLWPRV GAWEMKLFTA LREICTQDDN FKYLRAAVSR
LIEEPGTGVA PASVRSALAA NGKPRLFSTT CVPFLGVYVS QMQNVSRMPD YIDPTDPPAG
LRYNAATNQF YPFKNPDRFA TLQPLPSTVP LEPLINVEKA RKLADIVRNF VAGQHLAVNM
RFPEINHTLW KECMSIRRLS SEEVNGRLMA E
//
