ID A0A168D3J7_9BACL Unreviewed; 628 AA.
AC A0A168D3J7;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE SubName: Full=PTS glucose transporter subunit IIA {ECO:0000313|EMBL:OAB33839.1};
GN ORFNames=PGLA_23220 {ECO:0000313|EMBL:OAB33839.1};
OS Paenibacillus glacialis.
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX NCBI_TaxID=494026 {ECO:0000313|EMBL:OAB33839.1, ECO:0000313|Proteomes:UP000076967};
RN [1] {ECO:0000313|EMBL:OAB33839.1, ECO:0000313|Proteomes:UP000076967}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 22343 {ECO:0000313|EMBL:OAB33839.1,
RC ECO:0000313|Proteomes:UP000076967};
RA Shin S.-K., Yi H.;
RT "Draft genome sequence of Paenibacillus glacialis DSM 22343.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAB33839.1}.
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DR EMBL; LVJH01000070; OAB33839.1; -; Genomic_DNA.
DR RefSeq; WP_068537574.1; NZ_LVJH01000070.1.
DR AlphaFoldDB; A0A168D3J7; -.
DR STRING; 494026.PGLA_23220; -.
DR OrthoDB; 9764327at2; -.
DR Proteomes; UP000076967; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0008982; F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity; IEA:InterPro.
DR GO; GO:0009401; P:phosphoenolpyruvate-dependent sugar phosphotransferase system; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd00212; PTS_IIB_glc; 1.
DR Gene3D; 2.70.70.10; Glucose Permease (Domain IIA); 1.
DR Gene3D; 3.30.1360.60; Glucose permease domain IIB; 1.
DR InterPro; IPR011055; Dup_hybrid_motif.
DR InterPro; IPR036878; Glu_permease_IIB.
DR InterPro; IPR018113; PTrfase_EIIB_Cys.
DR InterPro; IPR001127; PTS_EIIA_1_perm.
DR InterPro; IPR003352; PTS_EIIC.
DR InterPro; IPR013013; PTS_EIIC_1.
DR InterPro; IPR001996; PTS_IIB_1.
DR NCBIfam; TIGR00826; EIIB_glc; 1.
DR NCBIfam; TIGR00830; PTBA; 1.
DR PANTHER; PTHR30009; CYTOCHROME C-TYPE SYNTHESIS PROTEIN AND PTS TRANSMEMBRANE COMPONENT; 1.
DR PANTHER; PTHR30009:SF4; PTS SYSTEM N-ACETYLGLUCOSAMINE-SPECIFIC EIICBA COMPONENT; 1.
DR Pfam; PF00358; PTS_EIIA_1; 1.
DR Pfam; PF00367; PTS_EIIB; 1.
DR Pfam; PF02378; PTS_EIIC; 1.
DR SUPFAM; SSF51261; Duplicated hybrid motif; 1.
DR SUPFAM; SSF55604; Glucose permease domain IIB; 1.
DR PROSITE; PS51093; PTS_EIIA_TYPE_1; 1.
DR PROSITE; PS51098; PTS_EIIB_TYPE_1; 1.
DR PROSITE; PS01035; PTS_EIIB_TYPE_1_CYS; 1.
DR PROSITE; PS51103; PTS_EIIC_TYPE_1; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphotransferase system {ECO:0000256|ARBA:ARBA00022683};
KW Sugar transport {ECO:0000256|ARBA:ARBA00022597,
KW ECO:0000313|EMBL:OAB33839.1}; Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 12..35
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 55..88
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 100..118
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 138..161
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 173..195
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 232..254
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 289..313
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 342..362
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..374
FT /note="PTS EIIC type-1"
FT /evidence="ECO:0000259|PROSITE:PS51103"
FT DOMAIN 386..468
FT /note="PTS EIIB type-1"
FT /evidence="ECO:0000259|PROSITE:PS51098"
FT DOMAIN 487..591
FT /note="PTS EIIA type-1"
FT /evidence="ECO:0000259|PROSITE:PS51093"
FT ACT_SITE 408
FT /note="Phosphocysteine intermediate; for EIIB activity"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00421"
SQ SEQUENCE 628 AA; 68870 MW; 5606CAB2BAE00F09 CRC64;
MNWLGSLQQL GRAVMLPTMV LPAAAILLSI GSLPWDAWGL PSIGDVSTWA GQGIFYFLPY
FFAVGVAWGL ANQAGPAGLA ALSGMFIYDQ VTRHYSDGSI QPSTLIGIIF GMIAGGLYNR
FKHIKLPEVV QFFGGSRFVL LIMGLLSAVF SWFMLGISPF LQRGLDELTQ LVLHLGGFGL
FLYGMLYRIL TAFGLHHLLN NVFWFQVGTF TTPDGIYVQG DLPRYFAGDP TAGSFMAGLF
PIMMFALPGI ALAIIHEARE DLKPKIKKTF LTAALVCFVT GVSEQIEFAF LFVAPYMFIV
HVILSGLAMW ITYALDIHHG FSYSAGVIDY ILNFHLSHNA WMLIPIGLAY GLIYYVLFRW
AIHRFQIPTP GREEGSTLED WAGNIPFQAP LILEALGGKE NVVRLESCVT RLRLTVKNDR
LIDTSALKLL GSAGSMKLGG GNVQVVFGTY SELIREEVNK LMQRDLPQVL FCAPMQGRML
PIGEVPDHIF AAKLVGDGVA FIPEKDELVS PVYGTILHIY PTMHAIGIST PEGLEVLLHI
GIDTSQLTGG DFKAVVKEGD VVVPGQLLIK FNLAYIRKHA ASLATPMVIT NPQRVKSWSF
APFKGVKKGQ ASVMSVVLHD RNVGGHET
//
