ID A0A168FA48_CORDF Unreviewed; 585 AA.
AC A0A168FA48;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Xanthine/uracil/vitamin C permease {ECO:0000313|EMBL:OAA74877.1};
GN ORFNames=LEL_06865 {ECO:0000313|EMBL:OAA74877.1};
OS Akanthomyces lecanii RCEF 1005.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Cordycipitaceae; Akanthomyces;
OC Cordyceps confragosa.
OX NCBI_TaxID=1081108 {ECO:0000313|EMBL:OAA74877.1, ECO:0000313|Proteomes:UP000076881};
RN [1] {ECO:0000313|EMBL:OAA74877.1, ECO:0000313|Proteomes:UP000076881}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RCEF 1005 {ECO:0000313|EMBL:OAA74877.1,
RC ECO:0000313|Proteomes:UP000076881};
RX PubMed=27071652; DOI=10.1093/gbe/evw082;
RA Shang Y., Xiao G., Zheng P., Cen K., Zhan S., Wang C.;
RT "Divergent and convergent evolution of fungal pathogenicity.";
RL Genome Biol. Evol. 8:1374-1387(2016).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. Azg-like subfamily. {ECO:0000256|ARBA:ARBA00005697}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAA74877.1}.
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DR EMBL; AZHF01000005; OAA74877.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A168FA48; -.
DR STRING; 1081108.A0A168FA48; -.
DR OrthoDB; 35157at2759; -.
DR Proteomes; UP000076881; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:InterPro.
DR GO; GO:1904823; P:purine nucleobase transmembrane transport; IEA:UniProt.
DR InterPro; IPR045018; Azg-like.
DR InterPro; IPR006043; NCS2.
DR PANTHER; PTHR43337; XANTHINE/URACIL PERMEASE C887.17-RELATED; 1.
DR PANTHER; PTHR43337:SF1; XANTHINE_URACIL PERMEASE C887.17-RELATED; 1.
DR Pfam; PF00860; Xan_ur_permease; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000076881};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 96..115
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 148..168
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 180..199
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 242..261
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 326..347
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 367..391
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 403..424
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 430..448
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 478..495
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 541..585
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 569..585
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 585 AA; 62518 MW; 89B7022BAC0667A9 CRC64;
MGWAENVDSR VAKSFVGRWF RLDGSGHPRE RKGSYFLTEM RAGLTTFFAM AYILAVNSSI
VSESGGTCVC NGGADDPLCN NNEEYAICIQ AIKRDVVTAT AAISAIATFF VGLLANMPVG
IAPGMGLNAY FAYTVVGFHG SGPVPYKVAL TAIFVEGFIF FGLALCGMRQ WLARAIPASI
KLATGAGIGL YLTLIGLTYS NGIGVIVGSQ ATPTELAGCH PANRDPKTGA CPGSDKMRNP
TMWIGIFCGG ILTVMLMMYR VKGAVIAGIL LVSIISWPRP TPVTYFPYTP VGDDAFDFFK
KVVTVHPIKN ILNVQEWNVS EYGGQFGLAL ITFLYVDILD CTGTLYSMAR FAGLIDPVTQ
DFEGSTLAYM TDAICISIGA VFGLPPVTAF VESGAGITEG GKTGLTAVMT GFCFFITIFF
APIFASIPPW ATGCVLIIVG SMMATAVVEI NWKYLGDAVP AFLTIAMMPF SYSIADGLIA
GVMSYIILNG SVWAIKKASG GRILPPNYDE RSGWTYKIPG GVLPPWMVRL SKGDKKFWKE
EPRAAAPATM TQKEADLASN HGSDHEQPAE APVTTTISEG HSKQQ
//
