ID A0A168FGT9_9MICO Unreviewed; 328 AA.
AC A0A168FGT9;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE SubName: Full=3-methyl-2-oxobutanoate dehydrogenase subunit beta {ECO:0000313|EMBL:ANC31711.1};
DE EC=1.2.4.4 {ECO:0000313|EMBL:ANC31711.1};
GN Name=bkdB_2 {ECO:0000313|EMBL:ANC31711.1};
GN ORFNames=I598_2170 {ECO:0000313|EMBL:ANC31711.1};
OS Isoptericola dokdonensis DS-3.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales;
OC Promicromonosporaceae; Isoptericola.
OX NCBI_TaxID=1300344 {ECO:0000313|EMBL:ANC31711.1, ECO:0000313|Proteomes:UP000076794};
RN [1] {ECO:0000313|EMBL:ANC31711.1, ECO:0000313|Proteomes:UP000076794}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DS-3 {ECO:0000313|EMBL:ANC31711.1,
RC ECO:0000313|Proteomes:UP000076794};
RA Kwon S.-K., Kim J.F.;
RT "Complete genome sequence of a soil Actinobacterium, Isoptericola
RT dokdonensis DS-3.";
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC Evidence={ECO:0000256|ARBA:ARBA00001964};
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DR EMBL; CP014209; ANC31711.1; -; Genomic_DNA.
DR RefSeq; WP_068202952.1; NZ_CP014209.1.
DR AlphaFoldDB; A0A168FGT9; -.
DR STRING; 1300344.I598_2170; -.
DR KEGG; ido:I598_2170; -.
DR PATRIC; fig|1300344.3.peg.2179; -.
DR OrthoDB; 3457658at2; -.
DR Proteomes; UP000076794; Chromosome.
DR GO; GO:0003863; F:3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity; IEA:UniProtKB-EC.
DR GO; GO:0000287; F:magnesium ion binding; IEA:UniProt.
DR CDD; cd07036; TPP_PYR_E1-PDHc-beta_like; 1.
DR Gene3D; 3.40.50.920; -; 1.
DR Gene3D; 3.40.50.970; -; 1.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR009014; Transketo_C/PFOR_II.
DR InterPro; IPR005475; Transketolase-like_Pyr-bd.
DR InterPro; IPR033248; Transketolase_C.
DR PANTHER; PTHR42980:SF1; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA, MITOCHONDRIAL; 1.
DR PANTHER; PTHR42980; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA-RELATED; 1.
DR Pfam; PF02779; Transket_pyr; 1.
DR Pfam; PF02780; Transketolase_C; 1.
DR SMART; SM00861; Transket_pyr; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
DR SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000313|EMBL:ANC31711.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000076794}.
FT DOMAIN 6..181
FT /note="Transketolase-like pyrimidine-binding"
FT /evidence="ECO:0000259|SMART:SM00861"
SQ SEQUENCE 328 AA; 34715 MW; 193E40D75B967785 CRC64;
MSTQTMPLAK AITAGLRATL EGDDKVMLMG EDIGRLGGVF RVTDGLQKDF GEHRVVDTPL
AESGIVGTAI GLAMRGYRPV CEIQFDGFVF PAFDQITTQL SKLHSRTGGR VQVPVVIRIP
YGGGIGAVEH HSESPETLFA HTAGLRVVSP STPQDAYDMI RAAVASPDPV VFFEPKGRYW
TKGDVDLDAP VPADVLGTAR VVRDGADVTL VAYGPTVATA LSAADALAAE GTSAEVVDLR
SISPMDVPTV AASVRRTGRC VVVHEAPTFL GAGAELAARI SEECFYSLEA PVLRVGGFHA
PYPVAKIEHD YLPSVDRVLD AVDRALAH
//
