ID A0A168HUD0_MUCCL Unreviewed; 941 AA.
AC A0A168HUD0;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:OAC99195.1};
GN ORFNames=MUCCIDRAFT_154095 {ECO:0000313|EMBL:OAC99195.1};
OS Mucor lusitanicus CBS 277.49.
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Mucorineae; Mucoraceae; Mucor.
OX NCBI_TaxID=747725 {ECO:0000313|EMBL:OAC99195.1, ECO:0000313|Proteomes:UP000077051};
RN [1] {ECO:0000313|EMBL:OAC99195.1, ECO:0000313|Proteomes:UP000077051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 277.49 {ECO:0000313|EMBL:OAC99195.1,
RC ECO:0000313|Proteomes:UP000077051};
RG DOE Joint Genome Institute;
RA Corrochano L.M., Kuo A., Marcet-Houben M., Polaino S., Salamov A.,
RA Villalobos J.M., Alvarez M.I., Avalos J., Benito E.P., Benoit I.,
RA Burger G., Camino L.P., Canovas D., Cerda-Olmedo E., Cheng J.-F.,
RA Dominguez A., Elias M., Eslava A.P., Glaser F., Grimwood J., Gutierrez G.,
RA Heitman J., Henrissat B., Iturriaga E.A., Lang B.F., Lavin J.L., Lee S.,
RA Li W., Lindquist E., Lopez-Garcia S., Luque E.M., Marcos A.T., Martin J.,
RA Mccluskey K., Medina H.R., Miralles-Duran A., Miyazaki A., Munoz-Torres E.,
RA Oguiza J.A., Ohm R., Olmedo M., Orejas M., Ortiz-Castellanos L.,
RA Pisabarro A.G., Rodriguez-Romero J., Ruiz-Herrera J., Ruiz-Vazquez R.,
RA Sanz C., Schackwitz W., Schmutz J., Shahriari M., Shelest E.,
RA Silva-Franco F., Soanes D., Syed K., Tagua V.G., Talbot N.J., Thon M.,
RA De Vries R.P., Wiebenga A., Yadav J.S., Braun E.L., Baker S., Garre V.,
RA Horwitz B., Torres-Martinez S., Idnurm A., Herrera-Estrella A.,
RA Gabaldon T., Grigoriev I.V.;
RT "Expansion of signal transduction pathways in fungi by whole-genome
RT duplication.";
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the RNR ribonuclease family.
CC {ECO:0000256|ARBA:ARBA00005785, ECO:0000256|RuleBase:RU003901}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAC99195.1}.
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DR EMBL; AMYB01000008; OAC99195.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A168HUD0; -.
DR STRING; 747725.A0A168HUD0; -.
DR VEuPathDB; FungiDB:QYA_154095; -.
DR OrthoDB; 945235at2759; -.
DR Proteomes; UP000077051; Unassembled WGS sequence.
DR GO; GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0004540; F:RNA nuclease activity; IEA:InterPro.
DR CDD; cd09862; PIN_Rrp44-like; 1.
DR Gene3D; 2.40.50.690; -; 1.
DR Gene3D; 2.40.50.700; -; 1.
DR Gene3D; 3.40.50.1010; 5'-nuclease; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR InterPro; IPR041505; Dis3_CSD2.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR029060; PIN-like_dom_sf.
DR InterPro; IPR002716; PIN_dom.
DR InterPro; IPR001900; RNase_II/R.
DR InterPro; IPR022966; RNase_II/R_CS.
DR InterPro; IPR033771; Rrp44_CSD1.
DR InterPro; IPR033770; RRP44_S1.
DR PANTHER; PTHR23355:SF35; EXOSOME COMPLEX EXONUCLEASE RRP44; 1.
DR PANTHER; PTHR23355; RIBONUCLEASE; 1.
DR Pfam; PF17849; OB_Dis3; 1.
DR Pfam; PF13638; PIN_4; 1.
DR Pfam; PF00773; RNB; 1.
DR Pfam; PF17216; Rrp44_CSD1; 1.
DR Pfam; PF17215; Rrp44_S1; 1.
DR SMART; SM00670; PINc; 1.
DR SMART; SM00955; RNB; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 3.
DR SUPFAM; SSF88723; PIN domain-like; 1.
DR PROSITE; PS01175; RIBONUCLEASE_II; 1.
PE 3: Inferred from homology;
KW Exosome {ECO:0000256|ARBA:ARBA00022835};
KW Reference proteome {ECO:0000313|Proteomes:UP000077051};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884}.
FT DOMAIN 60..178
FT /note="PIN"
FT /evidence="ECO:0000259|SMART:SM00670"
FT DOMAIN 465..797
FT /note="Ribonuclease II/R"
FT /evidence="ECO:0000259|SMART:SM00955"
SQ SEQUENCE 941 AA; 106446 MW; CD61EE9563020312 CRC64;
MLRSKSFVKR TRKGNVVKVV KEHYLRDDIP CSSEICNVCS KTSAPVLSST PKGTTTFKPH
YLIPDTNVFI SQLDIMEHPA IKDVIVLQTV REEIRHLSTP VYNRLNTILA DKTKRFYMFA
NEHQRDTFIE KLKGETPNDR NDRAIRVATK WFVDHLKANS SGENIDVIML SDDRGNREKA
KATGIKSCGV IEYVESIKDT PELLDMVSAP KAAAGEQVVY EEHLSPAQIQ NGIKKGTLIQ
APFNVSVHNV QEATVVGEVD GEVKTIFILG RKHFNRCIQG DIVAVELLPK SEWKRGASIA
IEEEDDDEEK MFGEEEVIDK MTESDSPVEP TGKVVGIIRK KWRPYCGFIV KKTVPKNTTS
GPVGVMFRAM DKRIPPIKIR TSQAQSLVGN RIVVSIDSWP TNSSFPMGHF VKTLGSSGDR
ETETEVLLLE HDVPYQEFSQ RVLQDLPVEG DQWVVQDKHL TQEKRRDFRD LDICSIDPPG
CTDIDDALHA RILPNGNWEV GVHIADVTYF VKHGMPMDVE AASRGTSVYL VDKRLDMLPS
LLGTNLCSLR SNVERLAFSC VWEMNENAEI VSVDFTKSVI RSKHSFTYDE AQTRIDDERM
QDPITKGIRV LNKFAKILRQ KRMENGALTL SSPEVRFNLE NDSQDPVDVE MKELKETNAL
VEEFMLLANI SVAKKIYSKF PSSAMLRKHA APPSNNFDSL RQILMEKGFV LETGSSKELA
DSLDKAVIPE DPYFNKLVRI MTTRCMMQAQ YFCSGTEIES EFKHYGLASP IYTHFTSPIR
RYADVIVHRL LQACIEPDLE YGQELTDTQK MKDLCDNLNF RNRMAQQASR SSVELFTSLY
FRNKVEVEDG RILRVLKNGI IVLVPKYGIE TIVYTSATVD GPSPFTYDEE AKSLVAGDVV
LKTFDSVKVE IRVEGDAEGM RQKMNMKLVE PFVEGLNKEI E
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