ID A0A168JNV6_MUCCL Unreviewed; 765 AA.
AC A0A168JNV6;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=Cullin {ECO:0000313|EMBL:OAD01425.1};
GN ORFNames=MUCCIDRAFT_112869 {ECO:0000313|EMBL:OAD01425.1};
OS Mucor lusitanicus CBS 277.49.
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Mucorineae; Mucoraceae; Mucor.
OX NCBI_TaxID=747725 {ECO:0000313|EMBL:OAD01425.1, ECO:0000313|Proteomes:UP000077051};
RN [1] {ECO:0000313|EMBL:OAD01425.1, ECO:0000313|Proteomes:UP000077051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 277.49 {ECO:0000313|EMBL:OAD01425.1,
RC ECO:0000313|Proteomes:UP000077051};
RG DOE Joint Genome Institute;
RA Corrochano L.M., Kuo A., Marcet-Houben M., Polaino S., Salamov A.,
RA Villalobos J.M., Alvarez M.I., Avalos J., Benito E.P., Benoit I.,
RA Burger G., Camino L.P., Canovas D., Cerda-Olmedo E., Cheng J.-F.,
RA Dominguez A., Elias M., Eslava A.P., Glaser F., Grimwood J., Gutierrez G.,
RA Heitman J., Henrissat B., Iturriaga E.A., Lang B.F., Lavin J.L., Lee S.,
RA Li W., Lindquist E., Lopez-Garcia S., Luque E.M., Marcos A.T., Martin J.,
RA Mccluskey K., Medina H.R., Miralles-Duran A., Miyazaki A., Munoz-Torres E.,
RA Oguiza J.A., Ohm R., Olmedo M., Orejas M., Ortiz-Castellanos L.,
RA Pisabarro A.G., Rodriguez-Romero J., Ruiz-Herrera J., Ruiz-Vazquez R.,
RA Sanz C., Schackwitz W., Schmutz J., Shahriari M., Shelest E.,
RA Silva-Franco F., Soanes D., Syed K., Tagua V.G., Talbot N.J., Thon M.,
RA De Vries R.P., Wiebenga A., Yadav J.S., Braun E.L., Baker S., Garre V.,
RA Horwitz B., Torres-Martinez S., Idnurm A., Herrera-Estrella A.,
RA Gabaldon T., Grigoriev I.V.;
RT "Expansion of signal transduction pathways in fungi by whole-genome
RT duplication.";
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- SIMILARITY: Belongs to the cullin family.
CC {ECO:0000256|ARBA:ARBA00006019, ECO:0000256|PROSITE-ProRule:PRU00330,
CC ECO:0000256|RuleBase:RU003829}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAD01425.1}.
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DR EMBL; AMYB01000006; OAD01425.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A168JNV6; -.
DR STRING; 747725.A0A168JNV6; -.
DR VEuPathDB; FungiDB:QYA_112869; -.
DR OrthoDB; 5474206at2759; -.
DR Proteomes; UP000077051; Unassembled WGS sequence.
DR GO; GO:0031461; C:cullin-RING ubiquitin ligase complex; IEA:InterPro.
DR GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
DR GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR Gene3D; 1.20.1310.10; Cullin Repeats; 4.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR045093; Cullin.
DR InterPro; IPR016157; Cullin_CS.
DR InterPro; IPR016158; Cullin_homology.
DR InterPro; IPR036317; Cullin_homology_sf.
DR InterPro; IPR001373; Cullin_N.
DR InterPro; IPR019559; Cullin_neddylation_domain.
DR InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11932; CULLIN; 1.
DR PANTHER; PTHR11932:SF168; CULLIN-3; 1.
DR Pfam; PF00888; Cullin; 1.
DR Pfam; PF10557; Cullin_Nedd8; 1.
DR SMART; SM00182; CULLIN; 1.
DR SMART; SM00884; Cullin_Nedd8; 1.
DR SUPFAM; SSF75632; Cullin homology domain; 1.
DR SUPFAM; SSF74788; Cullin repeat-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS01256; CULLIN_1; 1.
DR PROSITE; PS50069; CULLIN_2; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000077051};
KW Ubl conjugation {ECO:0000256|ARBA:ARBA00022843}.
FT DOMAIN 401..635
FT /note="Cullin family profile"
FT /evidence="ECO:0000259|PROSITE:PS50069"
SQ SEQUENCE 765 AA; 88345 MW; F10B027034D06217 CRC64;
MSLRKGRIRP VKRMPVMDHT QEYEEGFEIL SNAITVIFQK QARELSYELL YRTAYKLTIR
QFGERLYHDV AKVIADYLEA TAEQAIVPAF INTSVETSTA DEGAAFLKTV KKVWDDFKAA
IDLILQVLYY LNDRLPKYNL PSVDEMGLNL FRDKVIRSKQ YPIQQHLISA MLTQIQLERN
GDVIDRSAIQ SAVSMLVELT DPDTKLTVYA IDFEATYLDT TTSYYQIESQ KLVSSYDAPE
FMRKVEKRLE EEYERTVHCL SMTTEIKIRT IVETQLIANN LKTLMEMKNS GLESMLNADK
YGDLSRMYSL FSRVPAGLNE MRAFISNYIL TLGAEINQHI MSDLKSKAEK GSSSIAINWV
MEVLALQDKF DKILDLAASK DKSFQTVFNE AFEKFINDNQ KSAEFISLFI DENLKKGLKG
KSEDEVDDVL DKTITLFRFL QDKDVFERYY KQHLAKRLLL NRSVSDDAER GMLSKLKREC
GYQFTNKLEG MFNDMKLSTE MSTAFKEYLE KSTNPATNKL SLDASVTVLT STFWPMNLSA
SPKCVMPANV TQACKSFEHF YFDRHSGRRL TWQPQMGSAD IRAYFKKGKH LLNVSTYAMV
VLLLFNKNDT LSWEDIKNYT QIADQDLKRT LQSLACAKYK ILVKSSKGRD ILEDDSFAFN
QDFSSNMARI KIQALASRVE NDGERKNTQD KVDEERKHQI EASVVRIMKD RKTMEHNLLI
SEVTKQLSSR FMPSPVMIKK RIEALIDREY LERSAEDRRA YHYLA
//
