ID A0A168M313_MUCCL Unreviewed; 667 AA.
AC A0A168M313;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=Signal recognition particle subunit SRP72 {ECO:0000256|ARBA:ARBA00018350, ECO:0000256|PIRNR:PIRNR038922};
GN ORFNames=MUCCIDRAFT_91003 {ECO:0000313|EMBL:OAD04313.1};
OS Mucor lusitanicus CBS 277.49.
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Mucorineae; Mucoraceae; Mucor.
OX NCBI_TaxID=747725 {ECO:0000313|EMBL:OAD04313.1, ECO:0000313|Proteomes:UP000077051};
RN [1] {ECO:0000313|EMBL:OAD04313.1, ECO:0000313|Proteomes:UP000077051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 277.49 {ECO:0000313|EMBL:OAD04313.1,
RC ECO:0000313|Proteomes:UP000077051};
RG DOE Joint Genome Institute;
RA Corrochano L.M., Kuo A., Marcet-Houben M., Polaino S., Salamov A.,
RA Villalobos J.M., Alvarez M.I., Avalos J., Benito E.P., Benoit I.,
RA Burger G., Camino L.P., Canovas D., Cerda-Olmedo E., Cheng J.-F.,
RA Dominguez A., Elias M., Eslava A.P., Glaser F., Grimwood J., Gutierrez G.,
RA Heitman J., Henrissat B., Iturriaga E.A., Lang B.F., Lavin J.L., Lee S.,
RA Li W., Lindquist E., Lopez-Garcia S., Luque E.M., Marcos A.T., Martin J.,
RA Mccluskey K., Medina H.R., Miralles-Duran A., Miyazaki A., Munoz-Torres E.,
RA Oguiza J.A., Ohm R., Olmedo M., Orejas M., Ortiz-Castellanos L.,
RA Pisabarro A.G., Rodriguez-Romero J., Ruiz-Herrera J., Ruiz-Vazquez R.,
RA Sanz C., Schackwitz W., Schmutz J., Shahriari M., Shelest E.,
RA Silva-Franco F., Soanes D., Syed K., Tagua V.G., Talbot N.J., Thon M.,
RA De Vries R.P., Wiebenga A., Yadav J.S., Braun E.L., Baker S., Garre V.,
RA Horwitz B., Torres-Martinez S., Idnurm A., Herrera-Estrella A.,
RA Gabaldon T., Grigoriev I.V.;
RT "Expansion of signal transduction pathways in fungi by whole-genome
RT duplication.";
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of the signal recognition particle (SRP) complex, a
CC ribonucleoprotein complex that mediates the cotranslational targeting
CC of secretory and membrane proteins to the endoplasmic reticulum (ER).
CC {ECO:0000256|PIRNR:PIRNR038922}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496,
CC ECO:0000256|PIRNR:PIRNR038922}. Endoplasmic reticulum
CC {ECO:0000256|ARBA:ARBA00004240}.
CC -!- SIMILARITY: Belongs to the SRP72 family.
CC {ECO:0000256|ARBA:ARBA00007676, ECO:0000256|PIRNR:PIRNR038922}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAD04313.1}.
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DR EMBL; AMYB01000003; OAD04313.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A168M313; -.
DR STRING; 747725.A0A168M313; -.
DR VEuPathDB; FungiDB:QYA_91003; -.
DR OrthoDB; 91080at2759; -.
DR Proteomes; UP000077051; Unassembled WGS sequence.
DR GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.
DR GO; GO:0005786; C:signal recognition particle, endoplasmic reticulum targeting; IEA:UniProtKB-UniRule.
DR GO; GO:0008312; F:7S RNA binding; IEA:InterPro.
DR GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; IEA:UniProtKB-UniRule.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR InterPro; IPR013699; Signal_recog_part_SRP72_RNA-bd.
DR InterPro; IPR026270; SRP72.
DR InterPro; IPR031545; SRP72_TPR-like.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR14094; SIGNAL RECOGNITION PARTICLE 72; 1.
DR PANTHER; PTHR14094:SF9; SIGNAL RECOGNITION PARTICLE SUBUNIT SRP72; 1.
DR Pfam; PF08492; SRP72; 1.
DR Pfam; PF17004; SRP_TPR_like; 1.
DR PIRSF; PIRSF038922; SRP72; 1.
DR SMART; SM00028; TPR; 6.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS50005; TPR; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|PIRNR:PIRNR038922};
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Reference proteome {ECO:0000313|Proteomes:UP000077051};
KW Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274,
KW ECO:0000256|PIRNR:PIRNR038922};
KW Signal recognition particle {ECO:0000256|ARBA:ARBA00023135,
KW ECO:0000256|PIRNR:PIRNR038922};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT REPEAT 459..492
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT DOMAIN 552..590
FT /note="Signal recognition particle SRP72 subunit RNA-
FT binding"
FT /evidence="ECO:0000259|Pfam:PF08492"
FT REGION 545..667
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 667 AA; 73829 MW; EBE3BACAF21FE185 CRC64;
MASATKEQQI TQLFTELKKT VDEYDDERSL EICDKLIKLN PEDQLTLQCK VVTLIRLEKY
KDALTMIARQ FRNSDIDLSY EKIYCYYRTN QLAPAMELLQ ELKAKNASND PSLLYLEAQL
LYSQGQFEKA VQVYESLLKS SDKNSNLYDE IQVNLLAAKA GLLFSTNNKA AVKDKAELKE
SADLYEVAYN AASVYLARGD VKKAQEQLEL AHKQCSDRSQ GMSKEEQEEE LAVISTQLGY
TYQLQGRAND AMKIYRQLLN SSDVTVAAVV SNNVVALDQG KNTEEAAKHL KTATSKEADV
KLKNYQKRVI HMNESLLQLY SHKYSACRDQ AQKLIDKYPD NDNLYLILAS ATHHQHKAAK
AVEELKKYAE KKPASLAIRF ATIQLQLLES QPAAALSTLE SYLATVKGDK SSYYKPALIA
LLVWLYEQTG QSEKAMETLD EASSVWKNDA SFTSTAAPTS TIKQTAAFKL KTGRYQDAVV
DYEQLVKADP SDAQAIAGLI AAYAHVDPKK AEQYGNALPA ITLSHLDVAT LEKIVPGVKR
GYVKKDPNGV HVKKPKTKKK RATLYPKKMD PNVQPDPERW IPKYERSTFR MKGKNKKALN
KGPQGVSMEG GGIGGTGSAN IGGKKAASST AAAAQSPEPV KEKAVSTPTP AKSAASKKKK
GKGKNRK
//
