ID A0A168MF57_ABSGL Unreviewed; 997 AA.
AC A0A168MF57;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=DH domain-containing protein {ECO:0008006|Google:ProtNLM};
GN Name=ABSGL_03945.1 scaffold 4693 {ECO:0000313|EMBL:SAL98416.1};
OS Absidia glauca (Pin mould).
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Cunninghamellaceae; Absidia.
OX NCBI_TaxID=4829 {ECO:0000313|EMBL:SAL98416.1};
RN [1] {ECO:0000313|EMBL:SAL98416.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 101.48 {ECO:0000313|EMBL:SAL98416.1};
RA Evans L.H., Alamgir A., Owens N., Weber N.D., Virtaneva K., Barbian K.,
RA Babar A., Rosenke K.;
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; LT552071; SAL98416.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A168MF57; -.
DR STRING; 4829.A0A168MF57; -.
DR InParanoid; A0A168MF57; -.
DR OrthoDB; 23973at2759; -.
DR Proteomes; UP000078561; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd00014; CH_SF; 1.
DR CDD; cd05992; PB1; 1.
DR CDD; cd13246; PH_Scd1; 1.
DR CDD; cd00160; RhoGEF; 1.
DR Gene3D; 1.10.418.10; Calponin-like domain; 1.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR010481; Cdc24/Scd1_N.
DR InterPro; IPR033511; Cdc24/Scd1_PH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000219; DH-domain.
DR InterPro; IPR001331; GDS_CDC24_CS.
DR InterPro; IPR000270; PB1_dom.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR47339; CELL DIVISION CONTROL PROTEIN 24; 1.
DR PANTHER; PTHR47339:SF1; CELL DIVISION CONTROL PROTEIN 24; 1.
DR Pfam; PF06395; CDC24; 1.
DR Pfam; PF00564; PB1; 1.
DR Pfam; PF15411; PH_10; 1.
DR Pfam; PF00621; RhoGEF; 1.
DR SMART; SM00666; PB1; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00325; RhoGEF; 1.
DR SUPFAM; SSF54277; CAD & PB1 domains; 1.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS00741; DH_1; 1.
DR PROSITE; PS50010; DH_2; 1.
DR PROSITE; PS51745; PB1; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000078561}.
FT DOMAIN 257..430
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
FT DOMAIN 454..576
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 913..994
FT /note="PB1"
FT /evidence="ECO:0000259|PROSITE:PS51745"
FT REGION 1..72
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 634..907
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 13..71
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 637..653
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 659..728
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 751..771
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 835..854
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 879..905
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 997 AA; 112485 MW; 3AFFD7D1EFBCEEC2 CRC64;
MATPALKRRT PSLGATPTIS SPPTHSPFNS PTTTAPATTA TEASITSTIT NTSSTSSTIS
STSSKTPPPG SSLYHTCRLV LDKLALVDGM SYWLDLEEDN LSPSLSPINS SSPPLMPLST
SSPSLAAVNT DASSTAGSNN DPLSKLCYLC RRGTPLFTLF NALNTHQPLK MDPNPKLNQV
NSCKANVYHF LVACRKQLLF PEEELFTVSD LYVDDTNGFV KVVNTVLKLL QLLEDKGIIS
SHCANQDSCP MVPPKDIRDQ VVLELLSTER KYVQDLETLQ TYMRELQQQR ILSQDTVHYL
FGNLNALVDF QRRFLIQMEK TAENQPQDQH FGLLFSQMED AFSVYEPYCS NFYSAQDLVV
QEAPKLQKLN IMNPTHQLTS LLIKPIQRIC KYPLLLNELI KSTNKEWLTV PEMATGLDTM
RRVADKVNET QRKHENLQMV VELKRRVDDW KGISIDKCGQ LLLQDKMVVT AYDNEREMHV
FFFENRLLLC KENKDNTKNR LTKANTITMK KRRRGTLEPK GKIETSRIVS LQNVSSNGEW
ALMIEWKEHQ VEQFTLKFRN EEQYKLWEST LNKQKDRRAV AAASSLVYST SNIDLHSNDS
NVPTVASSSS NISIFNHPNY LTTLPLNPHV NDNWSFIDPD DEEDEVDSVE DDGEESSSGS
RSRSNSFSAQ ILNTFSTRPK FGRNNSTDIS GLKPLSTPAT TMTSGRSNTP GLNLQPLPRS
NNSNLYHHEQ PVPGDYFFYP SSPPPSNPSS PTSSSRVSPN NSSSGRTFRD HPSSQMLHHH
YLQHHQKQKP TVLPTPSEPM TPSMDYFATP TMDAFDSSLL TGRPGPSLSE QQHYDRHHHH
HHHHHHHHHQ RPPPAQSRSR AQSSPSISRR HDNRPDGYYP VQQQRQYSLS TTLPKVSSDK
KSASLSDQLA PGLRKVKLIY NDGVYSIIIV SQHISCEELM DRVEQKLQVV GDLPYYCGFR
LKYRDEDGDL ITINSTEDIQ MAFESDSTSS SHFYVCM
//
