ID   A0A168PIB6_ABSGL        Unreviewed;       450 AA.
AC   A0A168PIB6;
DT   06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT   06-JUL-2016, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   RecName: Full=Saccharopine dehydrogenase {ECO:0008006|Google:ProtNLM};
GN   Name=ABSGL_08238.1 scaffold 9741 {ECO:0000313|EMBL:SAM02445.1};
OS   Absidia glauca (Pin mould).
OC   Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC   Mucoromycetes; Mucorales; Cunninghamellaceae; Absidia.
OX   NCBI_TaxID=4829 {ECO:0000313|EMBL:SAM02445.1};
RN   [1] {ECO:0000313|EMBL:SAM02445.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 101.48 {ECO:0000313|EMBL:SAM02445.1};
RA   Evans L.H., Alamgir A., Owens N., Weber N.D., Virtaneva K., Barbian K.,
RA   Babar A., Rosenke K.;
RL   Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; LT553855; SAM02445.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A168PIB6; -.
DR   STRING; 4829.A0A168PIB6; -.
DR   InParanoid; A0A168PIB6; -.
DR   OMA; WNYKFTW; -.
DR   OrthoDB; 2184985at2759; -.
DR   Proteomes; UP000078561; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0009085; P:lysine biosynthetic process; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.1870.10; Domain 3, Saccharopine reductase; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR032095; Sacchrp_dh-like_C.
DR   InterPro; IPR005097; Sacchrp_dh_NADP.
DR   PANTHER; PTHR11133:SF25; ALPHA-AMINOADIPIC SEMIALDEHYDE SYNTHASE, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR11133; SACCHAROPINE DEHYDROGENASE; 1.
DR   Pfam; PF16653; Sacchrp_dh_C; 1.
DR   Pfam; PF03435; Sacchrp_dh_NADP; 1.
DR   SUPFAM; SSF55347; Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00023154};
KW   Lysine biosynthesis {ECO:0000256|ARBA:ARBA00023154};
KW   NADP {ECO:0000256|ARBA:ARBA00022857};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000078561}.
FT   DOMAIN          6..121
FT                   /note="Saccharopine dehydrogenase NADP binding"
FT                   /evidence="ECO:0000259|Pfam:PF03435"
FT   DOMAIN          125..443
FT                   /note="Saccharopine dehydrogenase-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF16653"
SQ   SEQUENCE   450 AA;  49611 MW;  5FB2A41C15EFBFB8 CRC64;
     MSEKKVLLLG SGFVAAPAVE YILRRPENKL TIASRRLENA QALVKEYPAA TAVSCDINDE
     KAIEDLVAQH DLVISLIPYI YHALVIKAAV KHKKNVVTTS YVSPAMMEYD QAAKDAGITV
     MNEIGLDPGI DHLYAVRTIE EVHNQGGKLL EFISFCGGLP APENSNNPFG YKFSWSARGV
     LLALKNTAKY LEDGKVVEVS GTALMDSARK LNAGYPGFAF VGYGNRDSTP YDKRYNIPEA
     QTIIRGTLRY DGFCQFVKAL FKLGFLSEDE QPHLAQNAPE IAWNQVIAKV SGAKSTQEED
     LKNAIIAKCD LDNDDNKAQI LDGMRWVGFF SDVKVTRRNN LLDTFCATLE EKMQYEEGER
     DLVFLQHRFE IELKDGSKQT RTSTLVEYGK PGGFSAMAKT VGVPCGIAVQ LILDGKLTKT
     GVLAPMSSDI NDPIIELLEQ EGIGMVEKIL
//