ID   A0A169N5U7_STRLU        Unreviewed;       211 AA.
AC   A0A169N5U7;
DT   06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT   06-JUL-2016, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   SubName: Full=N-acyl homoserine lactone hydrolase {ECO:0000313|EMBL:BAU81972.1};
GN   ORFNames=SLA_1021 {ECO:0000313|EMBL:BAU81972.1};
OS   Streptomyces laurentii.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=39478 {ECO:0000313|EMBL:BAU81972.1, ECO:0000313|Proteomes:UP000217676};
RN   [1] {ECO:0000313|EMBL:BAU81972.1, ECO:0000313|Proteomes:UP000217676}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 31255 {ECO:0000313|EMBL:BAU81972.1,
RC   ECO:0000313|Proteomes:UP000217676};
RA   Doi K., Fujino Y., Nagayoshi Y., Ohshima T., Ogata S.;
RT   "Complete Genome Sequence of Thiostrepton-Producing Streptomyces laurentii
RT   ATCC 31255.";
RL   Genome Announc. 4:e00360-16(2016).
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- SIMILARITY: Belongs to the metallo-beta-lactamase superfamily.
CC       {ECO:0000256|ARBA:ARBA00007749}.
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DR   EMBL; AP017424; BAU81972.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A169N5U7; -.
DR   KEGG; slau:SLA_1021; -.
DR   Proteomes; UP000217676; Chromosome.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR   InterPro; IPR001279; Metallo-B-lactamas.
DR   InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR   PANTHER; PTHR42978:SF2; METALLO-BETA-LACTAMASE DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR42978; QUORUM-QUENCHING LACTONASE YTNP-RELATED-RELATED; 1.
DR   Pfam; PF00753; Lactamase_B; 1.
DR   SMART; SM00849; Lactamase_B; 1.
DR   SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000313|EMBL:BAU81972.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000217676}.
FT   DOMAIN          28..198
FT                   /note="Metallo-beta-lactamase"
FT                   /evidence="ECO:0000259|SMART:SM00849"
SQ   SEQUENCE   211 AA;  23115 MW;  A5F0FCBAD5130AB7 CRC64;
     MISTTCLDLG YFTRPAAEWG GPYDRREPAL GYLVRHATGT VLFDTGMGEG SPEADAHYRP
     VRRALPVEPG DVDVIVNSHL HFDHIGGNQL FPGTPVLVQR TELATARAGD HTIDTLLPGV
     SYQEIDGEYA LAHGVRVVPT PGHTEGHQSL VLDHGDRMTV LAGQAYDFAH EFGTPYRPWL
     DRLGELAAGR PVRVLFAHDH DLWEGTLPAP R
//