ID A0A169NCW1_STRLU Unreviewed; 811 AA.
AC A0A169NCW1;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=p4 family phage/plasmid primase {ECO:0000313|EMBL:BAU83108.1};
GN ORFNames=SLA_2175 {ECO:0000313|EMBL:BAU83108.1};
OS Streptomyces laurentii.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=39478 {ECO:0000313|EMBL:BAU83108.1, ECO:0000313|Proteomes:UP000217676};
RN [1] {ECO:0000313|EMBL:BAU83108.1, ECO:0000313|Proteomes:UP000217676}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 31255 {ECO:0000313|EMBL:BAU83108.1,
RC ECO:0000313|Proteomes:UP000217676};
RA Doi K., Fujino Y., Nagayoshi Y., Ohshima T., Ogata S.;
RT "Complete Genome Sequence of Thiostrepton-Producing Streptomyces laurentii
RT ATCC 31255.";
RL Genome Announc. 4:e00360-16(2016).
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DR EMBL; AP017424; BAU83108.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A169NCW1; -.
DR KEGG; slau:SLA_2175; -.
DR Proteomes; UP000217676; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd01029; TOPRIM_primases; 1.
DR Gene3D; 3.40.1360.10; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR006500; Helicase_put_C_phage/plasmid.
DR InterPro; IPR014015; Helicase_SF3_DNA-vir.
DR InterPro; IPR045455; NrS-1_pol-like_helicase.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014818; Phage/plasmid_primase_P4_C.
DR InterPro; IPR034154; TOPRIM_DnaG/twinkle.
DR InterPro; IPR006171; TOPRIM_domain.
DR NCBIfam; TIGR01613; primase_Cterm; 1.
DR PANTHER; PTHR35372; ATP BINDING PROTEIN-RELATED; 1.
DR PANTHER; PTHR35372:SF2; SF3 HELICASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF08706; D5_N; 1.
DR Pfam; PF19263; DUF5906; 1.
DR Pfam; PF13155; Toprim_2; 1.
DR SMART; SM00885; D5_N; 1.
DR SMART; SM00493; TOPRIM; 1.
DR SUPFAM; SSF56731; DNA primase core; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51206; SF3_HELICASE_1; 1.
DR PROSITE; PS50880; TOPRIM; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000217676}.
FT DOMAIN 212..296
FT /note="Toprim"
FT /evidence="ECO:0000259|PROSITE:PS50880"
FT DOMAIN 519..678
FT /note="SF3 helicase"
FT /evidence="ECO:0000259|PROSITE:PS51206"
SQ SEQUENCE 811 AA; 88608 MW; 0DA5B7E4791EF37F CRC64;
MLFADLLGRF DGVNEHQDGG YVARCPAHDD GRPSLRLWRG EDGKVRITCR AGCATADVIG
AVRLGWSDLF DVSGPGATVS AERPELVSTR LVAGLAAYVD RTSSALGDWS SEWAERARTY
LADRFGLDVE TAADLRIGVD QGDRGDGFPY LSRQYRSHPR ITVPLAGWDG VARGLQGRDI
SGKCSARWVS LTNPKGHRWI PWGVLRGGGG YGTVLITEGP GDGLTAVACG YDAVVIRGAS
LAGSPELVAE LAEGLRGSLV ILCGDADRAG SGFTARLAAG LAEHGVTTHA LELPRPGWDL
TDWREDNPGQ FAAELHRAVK AARPVRDSAD IEDDARSAEL AARTGADTVT RDQGAEAAEI
LARLVGQLGE SDAMNAHALV GWVGGRIRYA PGLGFYSWDG RVWVRSDTRV RQEVHRMGAA
LVLAGQTQAA RGFTMTTRID SLMTELKSVP SVLVEAVDFD NRPDLLAFKN GVVDLRTGRL
RPHDMRDMLT YGLDLDYRAE ATCPRWERFL AEIFPGMPDM PAYIQRLVGY GITGHVTEQS
FAVLWGKGAN GKSVLVDTLT AVFRAISKTT PFATFEAKSS GGIPNDIAAL RGARLVMASE
GESGAPMSEA ILKRVTGKDM ISARYLRREF FEFKPSFLLM LATNHKPKFK SQDEGLWRRV
KLLPFLRYFA PHERDTELDA KLLEEAEGIA AWAVRGAVDW YRGGLRDPQV IEGASQEYRE
TSDQLAGFFP GVLEHASDDQ VMNGNEAFNS YLEWCEAENL PARERWTRRA FYDAMEERGI
YRRKTMRGIA LVGLREADAT PDTPGPGIFA N
//
