ID   A0A170XVY1_9ACTN        Unreviewed;       620 AA.
AC   A0A170XVY1;
DT   06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT   06-JUL-2016, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Cholesterol oxidase {ECO:0000313|EMBL:GAT82084.1};
GN   ORFNames=STXM2123_2785 {ECO:0000313|EMBL:GAT82084.1};
OS   Streptomyces sp. F-3.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1840095 {ECO:0000313|EMBL:GAT82084.1, ECO:0000313|Proteomes:UP000078145};
RN   [1] {ECO:0000313|EMBL:GAT82084.1, ECO:0000313|Proteomes:UP000078145}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Wang L.S., Gao P.J., Liu L., Zhang H.Q., Cheng Z., Sun X.M.;
RT   "Streptomyces sp. F-3 geneom sequencing.";
RL   Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GAT82084.1}.
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DR   EMBL; BDDR01000015; GAT82084.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A170XVY1; -.
DR   STRING; 1840095.STXM2123_2785; -.
DR   OrthoDB; 517968at2; -.
DR   Proteomes; UP000078145; Unassembled WGS sequence.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   GO; GO:0016614; F:oxidoreductase activity, acting on CH-OH group of donors; IEA:InterPro.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 3.
DR   InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR000172; GMC_OxRdtase_N.
DR   InterPro; IPR007867; GMC_OxRtase_C.
DR   PANTHER; PTHR47470; CHOLESTEROL OXIDASE; 1.
DR   PANTHER; PTHR47470:SF1; FAD-DEPENDENT OXIDOREDUCTASE 2 FAD BINDING DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF05199; GMC_oxred_C; 1.
DR   Pfam; PF00732; GMC_oxred_N; 1.
DR   Pfam; PF13450; NAD_binding_8; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR   PROSITE; PS51379; 4FE4S_FER_2; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000078145}.
FT   DOMAIN          219..249
FT                   /note="4Fe-4S ferredoxin-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51379"
FT   REGION          1..29
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   620 AA;  67049 MW;  9CF0BAF13DDE10C6 CRC64;
     MSQGRSARTR DEDAYAHDHD HDDSGTHDTR DDHYDYDVIV VGSGFGGSVS ALRLTEKGYR
     VGVLEAGRRF TRESLPKNSW DLKNYLWAPR LGMYGIQRIH LLGNVMVLAG AGVGGGSLNY
     ANTLYVPPKA FFDDPQWRDI TDWQEELKPY YDQARRMLGA RLNPTTTPSD VHLKAAAQRM
     GCGDTFHMAP VGVFFGDGKD ADGGTRAKAG ERVADPYFGG VGPDRNACIE CGECMTGCRH
     GAKNTLNENY LYLAEKAGAV VHPMTTVVSI TEDARGGYAV ATLPTDNRRK GAGRLFTARR
     VVLAAGTYGT QTLLHRMKAG GMLPYLSPRL GELTRTNSEA LVGAQTDNRR YRRATGKPKA
     DFTRGVAITS SVHPDENTHI EPVRYGRGSN AMGGLSILQV PYVEGSSRVA AWLRNVARHP
     LLFLRSLSNR RWSERTIIGL VMQSLDNSLT TYLKPSGIGK GLLTARQGHG APNPQQIRAA
     TEAATALAAE INGFAGSNVG ELMGTPLTAH FLGGCPIGAS RETGVIDPYH RLYGHPGISV
     VDGSAVSANL GVNPSLTITA QAERAMAYWP NKGEPDPRPP QGAAYRRLRP VKPRNPVVPE
     GAFGALRLPF LEVPAVPPKK
//