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Database: UniProt
Entry: A0A171DJY2_9ACTN
LinkDB: A0A171DJY2_9ACTN
Original site: A0A171DJY2_9ACTN 
ID   A0A171DJY2_9ACTN        Unreviewed;       604 AA.
AC   A0A171DJY2;
DT   06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT   06-JUL-2016, sequence version 1.
DT   18-JUL-2018, entry version 19.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=PS9374_04793 {ECO:0000313|EMBL:GAT69122.1};
OS   Planomonospora sphaerica.
OC   Bacteria; Actinobacteria; Streptosporangiales; Streptosporangiaceae;
OC   Planomonospora.
OX   NCBI_TaxID=161355 {ECO:0000313|EMBL:GAT69122.1, ECO:0000313|Proteomes:UP000077701};
RN   [1] {ECO:0000313|Proteomes:UP000077701}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM 9374 {ECO:0000313|Proteomes:UP000077701};
RA   Suzuki T., Dohra H., Kodani S.;
RT   "Planomonospora sphaerica JCM9374 whole genome shotgun sequence.";
RL   Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00747961}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:GAT69122.1}.
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DR   EMBL; BDCX01000012; GAT69122.1; -; Genomic_DNA.
DR   RefSeq; WP_068900267.1; NZ_BDCX01000012.1.
DR   EnsemblBacteria; GAT69122; GAT69122; PS9374_04793.
DR   Proteomes; UP000077701; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   Gene3D; 3.30.300.180; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR038454; DnaA_N_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000077701};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00747973};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00748008};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000077701}.
FT   DOMAIN      295    423       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      507    576       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     303    310       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   604 AA;  66048 MW;  4CF278645D0C63A8 CRC64;
     MDEMELGAVW ARVLASSLHE DVPPIHRAWL GQTVPFGLMN DTVVLAAPTD FARDVLENKL
     RPLVTQALSQ EMGRPMRFAV MVDPAASANA GPGPGAGGPG NAGRPGSGTS RPREAYPQDS
     GTGYPQGNGP QPGYAQGGNA QHHGGAGQQH PYPAARPAAP PSTDYPQPRP QGQGFSFPYP
     QGEGDYPQRE ENAQPYRPAP PAPAPPPAEQ DQGQGYGGRG YPPQPAPPRA EPGAFERPAP
     VPAPAQNRWD SRGGRTPGEP ARLNPKYTFE TFVIGSSNRF AHAAAVAVAE APAKAYNPLF
     IYGDSGLGKT HLLHAIGHYA QSLYDGARVR YVSSEEFTND FINSIRDHKA DNFRGRYRAV
     DILLVDDIQF LEGKEQTQEE FFHTFNTLHN ANKQIVISSD RAPKQLITLE DRLRNRFEWG
     LITDVQPPEL ETRIAILRKK AIQEGLAAPP EVLEYIASRI STNIRELEGA LIRVTAFASL
     NRQSVDLQLT EVVLKDLITE DADSEITIAT IMASTATYFG LSIDDLCGGS RSRVLVTARQ
     IAMYLCRELT DMSLPKIGQQ FGGRDHTTVM HADRKIRSLM AERRSIYNQV NELTTRIKQQ
     SRNG
//
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