ID   A0A171DN47_9ACTN        Unreviewed;       852 AA.
AC   A0A171DN47;
DT   06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT   06-JUL-2016, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   SubName: Full=Molybdopterin oxidoreductase {ECO:0000313|EMBL:GAT70492.1};
GN   ORFNames=PS9374_06174 {ECO:0000313|EMBL:GAT70492.1};
OS   Planomonospora sphaerica.
OC   Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC   Streptosporangiaceae; Planomonospora.
OX   NCBI_TaxID=161355 {ECO:0000313|EMBL:GAT70492.1, ECO:0000313|Proteomes:UP000077701};
RN   [1] {ECO:0000313|EMBL:GAT70492.1, ECO:0000313|Proteomes:UP000077701}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM 9374 {ECO:0000313|EMBL:GAT70492.1,
RC   ECO:0000313|Proteomes:UP000077701};
RA   Dohra H., Suzuki T., Inoue Y., Kodani S.;
RT   "Draft Genome Sequence of Planomonospora sphaerica JCM9374, a Rare
RT   Actinomycete.";
RL   Genome Announc. 4:e00779-16(2016).
RN   [2] {ECO:0000313|Proteomes:UP000077701}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM 9374 {ECO:0000313|Proteomes:UP000077701};
RA   Suzuki T., Dohra H., Kodani S.;
RT   "Planomonospora sphaerica JCM9374 whole genome shotgun sequence.";
RL   Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Mo-bis(molybdopterin guanine dinucleotide);
CC         Xref=ChEBI:CHEBI:60539; Evidence={ECO:0000256|ARBA:ARBA00001942};
CC   -!- COFACTOR:
CC       Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC         Evidence={ECO:0000256|ARBA:ARBA00001966};
CC   -!- PATHWAY: Nitrogen metabolism. {ECO:0000256|ARBA:ARBA00004909}.
CC   -!- SIMILARITY: Belongs to the prokaryotic molybdopterin-containing
CC       oxidoreductase family. NasA/NapA/NarB subfamily.
CC       {ECO:0000256|ARBA:ARBA00008747}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GAT70492.1}.
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DR   EMBL; BDCX01000017; GAT70492.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A171DN47; -.
DR   STRING; 161355.PS9374_06174; -.
DR   OrthoDB; 7376058at2; -.
DR   Proteomes; UP000077701; Unassembled WGS sequence.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0042128; P:nitrate assimilation; IEA:UniProtKB-KW.
DR   CDD; cd02791; MopB_CT_Nitrate-R-NapA-like; 1.
DR   Gene3D; 2.40.40.20; -; 1.
DR   Gene3D; 3.40.50.740; -; 1.
DR   Gene3D; 3.40.228.10; Dimethylsulfoxide Reductase, domain 2; 1.
DR   InterPro; IPR009010; Asp_de-COase-like_dom_sf.
DR   InterPro; IPR041957; CT_Nitrate-R-NapA-like.
DR   InterPro; IPR006657; MoPterin_dinucl-bd_dom.
DR   InterPro; IPR006656; Mopterin_OxRdtase.
DR   InterPro; IPR006963; Mopterin_OxRdtase_4Fe-4S_dom.
DR   InterPro; IPR006655; Mopterin_OxRdtase_prok_CS.
DR   PANTHER; PTHR43105:SF9; NITRATE REDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G15190)-RELATED; 1.
DR   PANTHER; PTHR43105; RESPIRATORY NITRATE REDUCTASE; 1.
DR   Pfam; PF00384; Molybdopterin; 1.
DR   Pfam; PF01568; Molydop_binding; 1.
DR   SUPFAM; SSF50692; ADC-like; 1.
DR   SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
DR   PROSITE; PS51669; 4FE4S_MOW_BIS_MGD; 1.
DR   PROSITE; PS00490; MOLYBDOPTERIN_PROK_2; 1.
PE   3: Inferred from homology;
KW   4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Molybdenum {ECO:0000256|ARBA:ARBA00022505};
KW   Nitrate assimilation {ECO:0000256|ARBA:ARBA00023063};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000077701}.
FT   DOMAIN          64..120
FT                   /note="4Fe-4S Mo/W bis-MGD-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51669"
FT   REGION          799..852
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   852 AA;  93075 MW;  6375E452FA538817 CRC64;
     MDDRIAEPWG PRTPYGPGPA IERFAASLPG WLRDLLPGEP GRRSAWPVRV DMFLQDGIAE
     SDVEEWVQAA SILHSNGDAM DIAVSGGRIV GVRGRAGDRV NHGRLDPKDL YGWQADSSPD
     RLTRPLVRED GKLVETDWDT AMGRIVARSK ELLAEPGGWG RFGFYTSGQL FLEEYYTLGV
     IGKAGIGTPH MDGNTRLCTA TAAAALKASF GTDGQPGSYT DVDHCDAIAL WGHNVAETQV
     VLWERMLDRR RGPRPPAMIA VDPRQTPVAR EADVHLAVRP GTNLALMNAL IHRLIERGWY
     DERYVRRHTL GFEELRRTVA ECTPQWAARI CDVPVRLIEQ AAEILGSCDR LLSTVLQGFY
     QSNQATAAAC QVNNIHLLRG MLGRPGAGLY QMNGQPTAQN TRETGADGDL PGMRNWDNPE
     HVRQLAELWN VDASVIPHWA PPTHALQIFR HAEQGSIKLL WISATNPAVS LPDLARIRRI
     LGKEDLFTVV QDIFLTETAR LADVVLPAAT WGEKQGTFTS VDRTVHLSDR AVDPPGEARS
     DLDIFLDYAR RMGFRDRAGA PLVKWHDPES AFEAWKACSA GRPCDYTGIT YDLLRGGSGV
     QWPCTRSAPR GTERLYAGGR FNTDPDYCET YGHDLATGAE YDARHYRALE PRGRAFLQAA
     PYEPSPEVPS EDYPMTLTTG RTVYHFHTRT KTGRTPQLND AAPEPWVEIS PGDAHTLGVT
     EGDLLHVESP RGRLEARARV CGTRPGVVFV PFHYGYWDLD APGPGEGAGR AANELTITSW
     DPVSKQPIYK VAAVRVGKAA PSGGTPSAAP TTGAAAPADP NVPATTGGSA AAVSSRISDH
     LSSRLPDRPG ET
//