ID A0A172Q9X8_9STRE Unreviewed; 1241 AA.
AC A0A172Q9X8;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE SubName: Full=Phosphoribosylformylglycinamidine synthase {ECO:0000313|EMBL:AND80266.1};
GN ORFNames=A0O21_09895 {ECO:0000313|EMBL:AND80266.1};
OS Streptococcus pantholopis.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=1811193 {ECO:0000313|EMBL:AND80266.1, ECO:0000313|Proteomes:UP000077317};
RN [1] {ECO:0000313|EMBL:AND80266.1, ECO:0000313|Proteomes:UP000077317}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TA 26 {ECO:0000313|EMBL:AND80266.1,
RC ECO:0000313|Proteomes:UP000077317};
RX PubMed=27226124; DOI=10.1099/ijsem.0.001189;
RA Bai X., Xiong Y., Lu S., Jin D., Lai X., Yang J., Niu L., Hu S., Meng X.,
RA Pu J., Ye C., Xu J.;
RT "Streptococcuspantholopis sp. nov., isolated from faeces of the Tibetan
RT antelope (Pantholops hodgsonii).";
RL Int. J. Syst. Evol. Microbiol. 66:3281-3286(2016).
RN [2] {ECO:0000313|Proteomes:UP000077317}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TA 26 {ECO:0000313|Proteomes:UP000077317};
RA Bai X.;
RT "Streptococcus antelopensis sp. nov., isolated from the feces of the
RT Tibetan antelope (Pantholops hodgsonii) in Hoh Xil National Nature Reserve,
RT Qinghai, China.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP014699; AND80266.1; -; Genomic_DNA.
DR RefSeq; WP_067064718.1; NZ_CP014699.1.
DR AlphaFoldDB; A0A172Q9X8; -.
DR STRING; 1811193.A0O21_09895; -.
DR KEGG; spat:A0O21_09895; -.
DR OrthoDB; 9804441at2; -.
DR Proteomes; UP000077317; Chromosome.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004642; F:phosphoribosylformylglycinamidine synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
DR CDD; cd02203; PurL_repeat1; 1.
DR CDD; cd02204; PurL_repeat2; 1.
DR Gene3D; 3.40.50.880; -; 1.
DR Gene3D; 3.90.650.10; PurM-like C-terminal domain; 1.
DR Gene3D; 3.30.1330.10; PurM-like, N-terminal domain; 2.
DR InterPro; IPR029062; Class_I_gatase-like.
DR InterPro; IPR010141; FGAM_synthase.
DR InterPro; IPR041609; PurL_linker.
DR InterPro; IPR010918; PurM-like_C_dom.
DR InterPro; IPR036676; PurM-like_C_sf.
DR InterPro; IPR036921; PurM-like_N_sf.
DR NCBIfam; TIGR01857; FGAM-synthase; 1.
DR PANTHER; PTHR10099; PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE; 1.
DR PANTHER; PTHR10099:SF1; PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE; 1.
DR Pfam; PF02769; AIRS_C; 1.
DR Pfam; PF18072; FGAR-AT_linker; 1.
DR Pfam; PF13507; GATase_5; 1.
DR SMART; SM01211; GATase_5; 1.
DR SUPFAM; SSF52317; Class I glutamine amidotransferase-like; 1.
DR SUPFAM; SSF56042; PurM C-terminal domain-like; 2.
DR SUPFAM; SSF55326; PurM N-terminal domain-like; 2.
PE 4: Predicted;
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Purine biosynthesis {ECO:0000256|ARBA:ARBA00022755};
KW Reference proteome {ECO:0000313|Proteomes:UP000077317}.
FT DOMAIN 182..228
FT /note="Phosphoribosylformylglycinamidine synthase linker"
FT /evidence="ECO:0000259|Pfam:PF18072"
FT DOMAIN 439..591
FT /note="PurM-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02769"
SQ SEQUENCE 1241 AA; 135706 MW; 45AF97E579311398 CRC64;
MNERIFVEKK SHFQVKSQSL AKELRHNLQL ESLTELRLVQ VYDVFNLSQE LAAAAQKHVF
SEQVTDNILT EKAVKELFES YVFFAIESLP GQFDQRAASA QEALLLLGSS DAVTVNTAQL
YLVNQDIAAK ELTAIKNYLL NPVDSRFKDI SAGMAYPDFS KSDETVAYLD FFADYTAEDF
AKYKADQGLA MEVEDLLFIQ DYFKAIGRVP TETELKVLDT YWSDHCRHTT FETELKAIDF
SASSFEQQLQ ATYEKYLAMR AELGRSDKPQ TLMDMATIFG RYERANGRLD DMEVSDEINA
CSIEIEVDVN GVKEPWLLMF KNETHNHPTE IEPFGGAATC IGGAIRDPLS GRSYVYQAMR
ISGAGDITRP ISSTRPGKLP QQVISKTAAQ GYSSYGNQIG LATTYVKEYF HPGFVAKRME
LGAVVGAAPK KNVVREKPQA GDLVILLGGK TGRDGIGGAT GSSKVQTVQS VETAGAEVQK
GNAIEERKIQ RLFRKGRVTR LIKKSNDFGA GGVCVAIGEL ADGLEIDLNK IPLKYQGLNG
TEIAISESQE RMSVVVRPEH TDLFIAECAR ENIEAVAVGV VTEKPHLVMT WNGQTIVDLE
RSFLDTNGVR VAVDAKVVDS AADLPEQRIT SAATLEKDAV NVLSDLNHAS QKGLQTIFDS
SVGRSTVNHP IGGRYQVTPA ESSVQKLPVQ NGETRTASVM AQGFNPYIAE WSPYHGGAYA
VIEAAARLAA TGGNWSKARF SYQEYFQRMD KQAERFGQPV AALLGSIEAQ IQLGLPSIGG
KDSMSGTFEE LTVPPTLVAF GVTTADVDKV LSPEFKAAGE TIYYIAGQVL SENIDFTLIK
ENLDKFAAIQ AKYKISSASA VKYGGVLESL ALASFGNHIG ASVEIEELEH SLTAQLGGFI
FTSGEDIAEA VKIGETTADF RLDVNGVHLS GTSLLKAFEQ PLEGVYPTEF TQTAQVEDLP
IIPSNNTVQA KEKVERPLVY IPVFPGTNSE YDSAKAFEKE GGEVRLVPFV TLNEAAIKES
VAVMVDQINQ ANILFLAGGF SAADEPDGSA KFIVNILLNR DVRQAIDKFI ERGGLIIGIC
NGFQALVKSG LLPYGDFEAA QKDSPTLFYN DANQHVAKMV ETRIANTNSP WLAGVEVGDI
HTIPVSHGEG KFVVSAWEFA QLRDKGQIFS QYVDFAGKPS MDSRYNPNGS YYAIEGITSE
NGQIIGKMGH SERYEEGLFQ NIPGNKEQLL FRSAVEYFTK S
//
