ID   A0A172TNM9_9BACL        Unreviewed;      1002 AA.
AC   A0A172TNM9;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   SubName: Full=Alpha-mannosidase {ECO:0000313|EMBL:ANE48648.1};
GN   ORFNames=SY83_01630 {ECO:0000313|EMBL:ANE48648.1};
OS   Paenibacillus swuensis.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX   NCBI_TaxID=1178515 {ECO:0000313|EMBL:ANE48648.1, ECO:0000313|Proteomes:UP000076927};
RN   [1] {ECO:0000313|EMBL:ANE48648.1, ECO:0000313|Proteomes:UP000076927}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DY6 {ECO:0000313|EMBL:ANE48648.1,
RC   ECO:0000313|Proteomes:UP000076927};
RA   Kim M.K., Srinivasan S., Lee J.-J.;
RT   "Paenibacillus swuensis/DY6/whole genome sequencing.";
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 38 family.
CC       {ECO:0000256|ARBA:ARBA00009792}.
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DR   EMBL; CP011388; ANE48648.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A172TNM9; -.
DR   STRING; 1178515.SY83_01630; -.
DR   KEGG; pswu:SY83_01630; -.
DR   PATRIC; fig|1178515.4.peg.302; -.
DR   OrthoDB; 9772207at2; -.
DR   Proteomes; UP000076927; Chromosome.
DR   GO; GO:0004559; F:alpha-mannosidase activity; IEA:InterPro.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006013; P:mannose metabolic process; IEA:InterPro.
DR   CDD; cd10789; GH38N_AMII_ER_cytosolic; 1.
DR   Gene3D; 2.60.40.2220; -; 1.
DR   Gene3D; 3.20.110.10; Glycoside hydrolase 38, N terminal domain; 1.
DR   Gene3D; 1.20.1270.50; Glycoside hydrolase family 38, central domain; 1.
DR   InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR   InterPro; IPR041147; GH38_C.
DR   InterPro; IPR011330; Glyco_hydro/deAcase_b/a-brl.
DR   InterPro; IPR011682; Glyco_hydro_38_C.
DR   InterPro; IPR015341; Glyco_hydro_38_cen.
DR   InterPro; IPR037094; Glyco_hydro_38_cen_sf.
DR   InterPro; IPR000602; Glyco_hydro_38_N.
DR   InterPro; IPR027291; Glyco_hydro_38_N_sf.
DR   InterPro; IPR028995; Glyco_hydro_57/38_cen_sf.
DR   PANTHER; PTHR46017; ALPHA-MANNOSIDASE 2C1; 1.
DR   PANTHER; PTHR46017:SF1; ALPHA-MANNOSIDASE 2C1; 1.
DR   Pfam; PF09261; Alpha-mann_mid; 1.
DR   Pfam; PF17677; Glyco_hydro38C2; 1.
DR   Pfam; PF07748; Glyco_hydro_38C; 1.
DR   Pfam; PF01074; Glyco_hydro_38N; 1.
DR   SMART; SM00872; Alpha-mann_mid; 1.
DR   SUPFAM; SSF88688; Families 57/38 glycoside transferase middle domain; 1.
DR   SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR   SUPFAM; SSF88713; Glycoside hydrolase/deacetylase; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00023295};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000076927}.
FT   DOMAIN          501..579
FT                   /note="Glycoside hydrolase family 38 central"
FT                   /evidence="ECO:0000259|SMART:SM00872"
SQ   SEQUENCE   1002 AA;  113486 MW;  3F3B56947BA4F6B3 CRC64;
     MPYESLTVER FHSLKDRIEQ SIYQPIESLS VQAWVTKEPV PYEERTSGKA ITLNPGDPWG
     ELWDCAWFHF QGIVPAAAAG QSVVLLIDVN GELCVVDADG SPYQGLTNIN SEYDYALGLP
     GKRVVYVAEQ AKGGERIDLW GDAGCNDLFG RYRSGKLKEA LIAVCLEENK QLYYDLEVLM
     ELADQLSNES SRKKQILQAL FEVSHVLMDI TPESVGAARH RLSVELKKRG GDPTIRVSAI
     GHAHMDLAWL WPIRETIRKG ARTFATALRM MEKYPDYVFG ASQPQLYEWI KQHYPALFES
     VKQRIKEGRW EVQGAMWVEP DSNVAGGEAL VRQILYGKRY FKQEFGIDVR MLWVPDIFGY
     SASLPQLLKK SGVDYMVTQK LSWNMYNDYP HHTFFWEGLD GSKVLTHLPP EDTYNSPSAP
     RSLVKIEKEY HDSGVSDRAL MLFGIGDGGG GPGEEHLERL KREKNLLGLP PVEQEPSIDF
     LDKLQEGASH YKTWKGELYL EKHQGTLTTQ ARNKKFNRRL EKSLREWEFA ASFASRACAV
     PYPKQELEEI WKEVLLYQFH DILPGSSIGR VYDESLARYE EITKTVEKGI EVAYGEIANN
     LNLSDYRDPV VYFNSLPWER AEWVQLKKGW MKAVVPSMGY CAVEPEEVVG VTEFVQLKAS
     SEGIENEEIR VVLNEAGVIV SLFDKREGRE LLQGGRTGNN LVLFDDRGGD AWDFPGDYRE
     RASIELQPAS TQAYIDGPYA VVEQHYVFGN SELTQRVKLS SESRQIVFET RVDWQESDKM
     LRSSFPLAIA TDLVTSEIQF GSIKRPTHRN TSWDTARDEI CAHHWIDVSE SRYGVTMLND
     SKYGHRVENG VLDINLLRSP AYPDPLADRA VHEFVYSILP HAGSCAEALV YKDGYELNTP
     LRSVKPASKS GTMAASDSLY KVDHPHIMIE AVKQAEDDHS LIIRLYETSG GQANVNLQVA
     HPYLSIEETN LMEETIASLE SDNGAVRLRF SAFEIKTIRI VM
//