ID A0A172TZ39_9BACT Unreviewed; 701 AA.
AC A0A172TZ39;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Peptidoglycan glycosyltransferase {ECO:0000313|EMBL:ANE52208.1};
GN ORFNames=SY85_18645 {ECO:0000313|EMBL:ANE52208.1};
OS Flavisolibacter tropicus.
OC Bacteria; Bacteroidota; Chitinophagia; Chitinophagales; Chitinophagaceae;
OC Flavisolibacter.
OX NCBI_TaxID=1492898 {ECO:0000313|EMBL:ANE52208.1, ECO:0000313|Proteomes:UP000077177};
RN [1] {ECO:0000313|Proteomes:UP000077177}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LCS9 {ECO:0000313|Proteomes:UP000077177};
RA Kim M.K., Srinivasan S., Lee J.-J.;
RT "Flavisolibacter sp./LCS9/ whole genome sequencing.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ANE52208.1, ECO:0000313|Proteomes:UP000077177}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LCS9 {ECO:0000313|EMBL:ANE52208.1,
RC ECO:0000313|Proteomes:UP000077177};
RX PubMed=27259556; DOI=10.1099/ijsem.0.001207;
RA Lee J.J., Kang M.S., Kim G.S., Lee C.S., Lim S., Lee J., Roh S.H., Kang H.,
RA Ha J.M., Bae S., Jung H.Y., Kim M.K.;
RT "Flavisolibacter tropicus sp. nov., isolated from tropical soil.";
RL Int. J. Syst. Evol. Microbiol. 66:3413-3419(2016).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
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DR EMBL; CP011390; ANE52208.1; -; Genomic_DNA.
DR RefSeq; WP_066406452.1; NZ_CP011390.1.
DR AlphaFoldDB; A0A172TZ39; -.
DR STRING; 1492898.SY85_18645; -.
DR KEGG; fla:SY85_18645; -.
DR PATRIC; fig|1492898.3.peg.4059; -.
DR OrthoDB; 9766847at2; -.
DR Proteomes; UP000077177; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR GO; GO:0009002; F:serine-type D-Ala-D-Ala carboxypeptidase activity; IEA:InterPro.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0009252; P:peptidoglycan biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR InterPro; IPR017790; Penicillin-binding_protein_2.
DR NCBIfam; TIGR03423; pbp2_mrdA; 1.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF2; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE MRDA; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000077177};
KW Transferase {ECO:0000313|EMBL:ANE52208.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..30
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 51..219
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 256..598
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 701 AA; 78163 MW; 2F5D48E1A3849E1D CRC64;
MSVFNQSRSY IIRLLFLVVF LVIIGQLFNL QVLSGKYQQL AQANAVFRKV VYPPRGIIFD
RKGKAILNNT LMYDLMVTPS QVKNVDTSFL CQLLEIDTAV FKQRMVEAIV RNGRFRPSSF
EELLSPEKYA RLEENMWRFS SGFYLQQRPV RVYPFNAAPH VMGYVGEVDS GIIARSGGFY
QAGDYVGRSG LEAYYERVLM GQRGVQFMIK DNKNRLVGQY ENGQFDTAAI AGRGLRTFID
IDIQQLAEKL MANKVGAVVA LEPKTGGIIA MVSGPNYDPN ALTGSEKKKN YSKLVLDVAG
PLLNRAIAGT YPPGSTFKPI GGLVALDEGL ITPRFGYPCG GRYYACGIGK PACTHSGGGH
AATLRLAIAN SCNSYFTHVY RMAVDNPKYR NVEEGYAVWR HYLNNFGLGV QLGVDLPGEY
RKSGIPDTSV YNRVYRNSWS SCTNLTLGIG QDMMLATPLQ LANSMCIIAN KGYYYTPHFV
RDIDGETKDD TILNKFRQKH EVLTHISDTA FEAVISGMQD VVEIGTARVA KVPGFNVCAK
TGTAENYRII DRKKVKLKDN SMFVCFAPRE NPKIAIAVVV ENAGFGATWG GNIAQLLMEK
YLTDSLRPER AKEAERIASS NLMPPYLSRL QYIEDSTRAR LYFDLTKDSS YLRKYIHRGL
PSAPAKKDSS APKPKTRLAY LPIWEAVLPK ELIDLKKKSV A
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