ID A0A172UUD5_9MYCO Unreviewed; 639 AA.
AC A0A172UUD5;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Acetoacetate-CoA ligase {ECO:0000313|EMBL:ANE82701.1};
GN ORFNames=A7U43_06700 {ECO:0000313|EMBL:ANE82701.1};
OS Mycobacterium adipatum.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium.
OX NCBI_TaxID=1682113 {ECO:0000313|EMBL:ANE82701.1, ECO:0000313|Proteomes:UP000077143};
RN [1] {ECO:0000313|EMBL:ANE82701.1, ECO:0000313|Proteomes:UP000077143}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YC-RL4 {ECO:0000313|EMBL:ANE82701.1,
RC ECO:0000313|Proteomes:UP000077143};
RA Ren L., Fan S., Ruth N., Jia Y., Wang J., Qiao C.;
RT "Complete genome sequence of a phthalic acid esters degrading Mycobacterium
RT sp. YC-RL4.";
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP015596; ANE82701.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A172UUD5; -.
DR STRING; 1682113.A7U43_06700; -.
DR KEGG; madi:A7U43_06700; -.
DR OrthoDB; 9803968at2; -.
DR Proteomes; UP000077143; Chromosome.
DR GO; GO:0030729; F:acetoacetate-CoA ligase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR005914; Acac_CoA_synth.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR NCBIfam; TIGR01217; ac_ac_CoA_syn; 1.
DR PANTHER; PTHR42921; ACETOACETYL-COA SYNTHETASE; 1.
DR PANTHER; PTHR42921:SF1; ACETOACETYL-COA SYNTHETASE; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:ANE82701.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000077143}.
FT DOMAIN 32..83
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 89..458
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 525..600
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 639 AA; 69129 MW; B489BC779D610A22 CRC64;
MSTAPQWQPT AADIAEARVT DFARFAGAPA EYHALWQWSV DEPAAFWGAL WEYFGLGEMP
GEVLARTDMP GAQWFPGVQL NFVDQVVRQA RTDRPAIRCV SEDTPTADLS WAELLRRTAG
FAQTLIDLGV RAGDRVVGYL PNIAEAVIAF LGTAAVGAVW SACGQDYSAK AALDRLGQLE
PVVLVTTDGY RFGGKFHDKS AEVAALRDGL PTLRATISVS RVAPVPQDHL DWETATATGA
ELGTVAVGFD HPLWILFSSG TTGLPKGIMH GHGGVLLEHL KAVALQSDIG ERDTFFWYTS
PSWMMWNFQI AGLLVGATIV CYDGSPSYPT PDALWAMAAD LGVTVLGTSP GYVLGCMKAG
AVPRSEHDLS ALRTVGITGS SLPPSTSLWM RDNIGEHVQI ASISGGTDVV SAFIGGVRTV
PVWPGELSAP YLGVALDAWD ESGNPVRGEV GELVVTKPLP SMPVAFWNDP DGSRYRDAYF
EMFPGVWRHG DWITITDHGS VIVHGRSDST LNRHGIRMGS ADIYQAVERL PEIAEALVIG
AEQPDGGYWM PLFVVLAEGV ELDDALRDKV KSTIRAEVSP RHVPDDIILA PGIPHTRTGK
KLEVPIKKLF QGAEAEKVVE RSAVDDPDLL QWYVTQRRT
//
