ID A0A172Y0G2_9FLAO Unreviewed; 210 AA.
AC A0A172Y0G2;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Alkyl hydroperoxide reductase {ECO:0000313|EMBL:ANF52748.1};
GN ORFNames=A0O34_20510 {ECO:0000313|EMBL:ANF52748.1};
OS Chryseobacterium glaciei.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales; Weeksellaceae;
OC Chryseobacterium group; Chryseobacterium.
OX NCBI_TaxID=1685010 {ECO:0000313|EMBL:ANF52748.1, ECO:0000313|Proteomes:UP000077824};
RN [1] {ECO:0000313|EMBL:ANF52748.1, ECO:0000313|Proteomes:UP000077824}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IHBB 10212 {ECO:0000313|EMBL:ANF52748.1,
RC ECO:0000313|Proteomes:UP000077824};
RA Pal M., Swarnkar M.K., Kaushal K., Chhibber S., Singh A.K., Gulati A.;
RT "Complete Genome Sequence of Chryseobacterium sp. IHBB 10212.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Thiol-specific peroxidase that catalyzes the reduction of
CC hydrogen peroxide and organic hydroperoxides to water and alcohols,
CC respectively. Plays a role in cell protection against oxidative stress
CC by detoxifying peroxides. {ECO:0000256|ARBA:ARBA00037420}.
CC -!- SIMILARITY: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
CC {ECO:0000256|ARBA:ARBA00009796}.
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DR EMBL; CP015199; ANF52748.1; -; Genomic_DNA.
DR RefSeq; WP_066758845.1; NZ_CP015199.1.
DR AlphaFoldDB; A0A172Y0G2; -.
DR STRING; 1685010.A0O34_20510; -.
DR KEGG; chh:A0O34_20510; -.
DR OrthoDB; 9812811at2; -.
DR Proteomes; UP000077824; Chromosome.
DR GO; GO:0051920; F:peroxiredoxin activity; IEA:InterPro.
DR CDD; cd03015; PRX_Typ2cys; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR InterPro; IPR000866; AhpC/TSA.
DR InterPro; IPR024706; Peroxiredoxin_AhpC-typ.
DR InterPro; IPR019479; Peroxiredoxin_C.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR InterPro; IPR013766; Thioredoxin_domain.
DR PANTHER; PTHR10681; THIOREDOXIN PEROXIDASE; 1.
DR PANTHER; PTHR10681:SF128; THIOREDOXIN-DEPENDENT PEROXIDE REDUCTASE, MITOCHONDRIAL; 1.
DR Pfam; PF10417; 1-cysPrx_C; 1.
DR Pfam; PF00578; AhpC-TSA; 1.
DR PIRSF; PIRSF000239; AHPC; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
DR PROSITE; PS51352; THIOREDOXIN_2; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 2..177
FT /note="Thioredoxin"
FT /evidence="ECO:0000259|PROSITE:PS51352"
FT ACT_SITE 51
FT /note="Cysteine sulfenic acid (-SOH) intermediate; for
FT peroxidase activity"
FT /evidence="ECO:0000256|PIRSR:PIRSR000239-1"
SQ SEQUENCE 210 AA; 23872 MW; 6B116AE4ABCD6ADF CRC64;
MSLVGKKFPN VAIDAMSEMG DDLRINIFEE TTKNQQKVIL FWYPKDFTFV CPTELHAFQE
ALGEFEKRNT KVIGASCDTN EVHFAWLNVS KDNGGIEGVT YPLLADTHRQ LANMLGIVDQ
DFEYNDEGEE VFTGSNVTYR ATYLIDETGK VFHESVNDMP LGRNVKEYLR LIDAYTHVQK
HGEVCPANWE EGKDAMKADR NSTAEYLAKN
//
