ID A0A173L0I3_9SPHN Unreviewed; 355 AA.
AC A0A173L0I3;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Alpha-pyrone synthesis polyketide synthase-like Pks18 {ECO:0000313|EMBL:ANI79055.1};
GN ORFNames=EP837_02660 {ECO:0000313|EMBL:ANI79055.1};
OS Sphingobium sp. EP60837.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Sphingobium.
OX NCBI_TaxID=1855519 {ECO:0000313|EMBL:ANI79055.1, ECO:0000313|Proteomes:UP000078304};
RN [1] {ECO:0000313|EMBL:ANI79055.1, ECO:0000313|Proteomes:UP000078304}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EP60837 {ECO:0000313|EMBL:ANI79055.1,
RC ECO:0000313|Proteomes:UP000078304};
RA Lee C.-M., Yoon S.-H., Kim B.-Y.;
RT "Complete genome sequence of a organophosphorus pesticides.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Chalcone/stilbene
CC synthases family. {ECO:0000256|ARBA:ARBA00005531}.
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DR EMBL; CP015987; ANI79055.1; -; Genomic_DNA.
DR RefSeq; WP_066529465.1; NZ_CP015987.1.
DR AlphaFoldDB; A0A173L0I3; -.
DR STRING; 1855519.EP837_02660; -.
DR KEGG; sphb:EP837_02660; -.
DR PATRIC; fig|1855519.3.peg.2724; -.
DR OrthoDB; 9786288at2; -.
DR Proteomes; UP000078304; Chromosome 2.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR012328; Chalcone/stilbene_synt_C.
DR InterPro; IPR001099; Chalcone/stilbene_synt_N.
DR InterPro; IPR011141; Polyketide_synthase_type-III.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR11877; HYDROXYMETHYLGLUTARYL-COA SYNTHASE; 1.
DR PANTHER; PTHR11877:SF46; TYPE III POLYKETIDE SYNTHASE A; 1.
DR Pfam; PF02797; Chal_sti_synt_C; 1.
DR Pfam; PF00195; Chal_sti_synt_N; 1.
DR PIRSF; PIRSF000451; PKS_III; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000078304}.
FT DOMAIN 4..210
FT /note="Chalcone/stilbene synthase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00195"
FT DOMAIN 224..349
FT /note="Chalcone/stilbene synthase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02797"
FT ACT_SITE 149
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000451-1"
SQ SEQUENCE 355 AA; 38197 MW; 63582A41CB08557C CRC64;
MSERRACINA IGCATPGQDV HLPFIRWASE QLEDERARGL FTRMAERSGI DHRWSVLPSV
EGGSPVDAGG FYAEAMPSTS QRMRLYRCYA PALALSAIEA LKVNTNIDGI THLVVASCTG
FVAPGIDQII AEALDLAGVE RTLVGFMGCY AAVAALRTAR HIVRSEPDAR VLVVTVELSS
LHLQAEQQLE RLLMMLQFGD GAAAALVSAE NCGFAMETLF AINLAESADL IRWEIGDTGF
IMHLSGEVPG RIQTALRDES VRERVCGSME PAMISNWAVH AGGRSILDAV EHGLELRDNA
LAFSRGVLAR YGNMSSATLM FILADLLDQD RQGQGVALAF GPGVAAEGFR FCRAG
//
