ID A0A173LLE1_9ACTN Unreviewed; 169 AA.
AC A0A173LLE1;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE RecName: Full=dUTP diphosphatase {ECO:0000256|ARBA:ARBA00012379};
DE EC=3.6.1.23 {ECO:0000256|ARBA:ARBA00012379};
GN ORFNames=BJL86_1561 {ECO:0000313|EMBL:ANI92338.1};
OS Dietzia timorensis.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Dietziaceae;
OC Dietzia.
OX NCBI_TaxID=499555 {ECO:0000313|EMBL:ANI92338.1, ECO:0000313|Proteomes:UP000186104};
RN [1] {ECO:0000313|EMBL:ANI92338.1, ECO:0000313|Proteomes:UP000186104}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ID05-A0528 {ECO:0000313|EMBL:ANI92338.1,
RC ECO:0000313|Proteomes:UP000186104};
RA Wu X.;
RT "Complete genome sequence of a saline-alkali tolerant type strain Dietzia
RT timorensis ID05-A0528T.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=dUTP + H2O = diphosphate + dUMP + H(+); Xref=Rhea:RHEA:10248,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:33019,
CC ChEBI:CHEBI:61555, ChEBI:CHEBI:246422; EC=3.6.1.23;
CC Evidence={ECO:0000256|ARBA:ARBA00000878};
CC -!- SIMILARITY: Belongs to the dUTPase family.
CC {ECO:0000256|ARBA:ARBA00006581}.
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DR EMBL; CP015961; ANI92338.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A173LLE1; -.
DR STRING; 499555.BJL86_1561; -.
DR KEGG; dtm:BJL86_1561; -.
DR Proteomes; UP000186104; Chromosome.
DR GO; GO:0004170; F:dUTP diphosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR GO; GO:0006226; P:dUMP biosynthetic process; IEA:InterPro.
DR GO; GO:0046081; P:dUTP catabolic process; IEA:InterPro.
DR CDD; cd07557; trimeric_dUTPase; 1.
DR Gene3D; 2.70.40.10; -; 1.
DR InterPro; IPR008181; dUTPase.
DR InterPro; IPR029054; dUTPase-like.
DR InterPro; IPR036157; dUTPase-like_sf.
DR InterPro; IPR033704; dUTPase_trimeric.
DR NCBIfam; TIGR00576; dut; 1.
DR PANTHER; PTHR11241; DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE; 1.
DR PANTHER; PTHR11241:SF0; DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE; 1.
DR Pfam; PF00692; dUTPase; 1.
DR SUPFAM; SSF51283; dUTPase-like; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:ANI92338.1};
KW Nucleotide metabolism {ECO:0000256|ARBA:ARBA00023080}.
FT DOMAIN 31..163
FT /note="dUTPase-like"
FT /evidence="ECO:0000259|Pfam:PF00692"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 169 AA; 17667 MW; D4AD11DA6034853F CRC64;
MSETPATPSS TPSAAGGPGE LLVHRLDPEL PMPVRGHADD AGIDVYSAED VSLQPGARHL
TGTGLAVRIP PGFVGLMHPR SGLAHKAGLS MVNTPGTIDA GYTGELKVNL INHDPAEPIH
IRRGDRIAQL LVQRVELWPV REVESVAELG ESARGAKGFG STGGHDRLG
//
