ID   A0A173LXU6_9MICO        Unreviewed;       734 AA.
AC   A0A173LXU6;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE            EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
GN   ORFNames=AUMI_111510 {ECO:0000313|EMBL:BAU99693.1};
OS   Aurantimicrobium minutum.
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC   Aurantimicrobium.
OX   NCBI_TaxID=708131 {ECO:0000313|EMBL:BAU99693.1, ECO:0000313|Proteomes:UP000243847};
RN   [1] {ECO:0000313|EMBL:BAU99693.1, ECO:0000313|Proteomes:UP000243847}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KNC {ECO:0000313|EMBL:BAU99693.1,
RC   ECO:0000313|Proteomes:UP000243847};
RA   Nakai R., Fujisawa T., Nakamura Y., Nishide H., Uchiyama I., Baba T.,
RA   Toyoda A., Fujiyama A., Naganuma T., Niki H.;
RT   "Complete Genome Sequence of Aurantimicrobium minutum Type Strain KNCT, a
RT   Planktonic Ultramicrobacterium Isolated from River Water.";
RL   Genome Announc. 4:e00616-16(2016).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC         Evidence={ECO:0000256|ARBA:ARBA00034618};
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DR   EMBL; AP017457; BAU99693.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A173LXU6; -.
DR   KEGG; amin:AUMI_111510; -.
DR   OrthoDB; 9787585at2; -.
DR   Proteomes; UP000243847; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR   InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR014016; UvrD-like_ATP-bd.
DR   PANTHER; PTHR11070:SF2; ATP-DEPENDENT DNA HELICASE SRS2; 1.
DR   PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR   Pfam; PF00580; UvrD-helicase; 1.
DR   Pfam; PF13361; UvrD_C; 2.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000243847}.
FT   DOMAIN          255..556
FT                   /note="UvrD-like helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51198"
FT   BINDING         276..283
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ   SEQUENCE   734 AA;  81462 MW;  FB79AD58240D27AC CRC64;
     MPNIQLSKLK NQNHEGPVRA KILTFLQKLA EDDTTPGLHI EKMQQQADPK ARTGRVDQSL
     RAVLYRIDRA GEERLYVYAG TWAHDEAIRR AQTLVLQVNP INGIPEFVES APTGIPSYVP
     QTVTPIVEDP TSDVPLQPFL KQFGFSHADL TESLGFDASA AEALLHATSE DELLSLAESF
     ENEWQVNAAL ALAVGEPIDK IREDLAIGEK PEPGDDAFVA AFEHPASKMQ FTFIDNDQEL
     KNIIEGGDFG AWRVFLHPEQ RSYAEKSYNG PFRLTGGAGT GKTVVLLHRA RNLHHRDFKK
     RIILTTFTKA LASALTRDLE RLDPTVSLAS SLGKEGVLVR GIDQLAAEIR DSNPELFWKS
     AENVFGAATE PRSKLVSNET GWREAIEDSD TVLPAELQSP TFYETEYLQV VLPARITKLD
     EYLQVRRPGR GVALDRTKRT LVWKIIESHR KASSHLGRIN FAEVSAVAVS VLQNGSAVSV
     ADSVLVDEAQ DLSPIHWQLL RALAPEGQDD LFIAEDSHQR IYGQKVVLSR FGIRITGRSK
     RLTLNYRTTQ QNLHFALGVL EGVQYLDSEE AEETTHGYKS SRRGPTPELL ASQTEVDQFE
     QIAALIKTWI DGGVPQQDIA VLCRSNTKRD QLRAQLNDRG VPTVVLEPGE SAAKKPVLMT
     MYKSKGMEFS RVILFDVSAG SIPNPVGLQN TAPEDLDDFL LRERSLLYVA ASRARDELVI
     SWQGYPSELL GAVV
//