ID A0A173MFU7_9BACT Unreviewed; 258 AA.
AC A0A173MFU7;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE RecName: Full=tRNA(His) guanylyltransferase {ECO:0000256|ARBA:ARBA00012511};
DE EC=2.7.7.79 {ECO:0000256|ARBA:ARBA00012511};
GN ORFNames=SAMN05421788_107126 {ECO:0000313|EMBL:SIT27061.1};
OS Filimonas lacunae.
OC Bacteria; Bacteroidota; Chitinophagia; Chitinophagales; Chitinophagaceae;
OC Filimonas.
OX NCBI_TaxID=477680 {ECO:0000313|EMBL:SIT27061.1, ECO:0000313|Proteomes:UP000186917};
RN [1] {ECO:0000313|Proteomes:UP000186917}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 21054 {ECO:0000313|Proteomes:UP000186917};
RA Varghese N., Submissions S.;
RL Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SIMILARITY: Belongs to the tRNA(His) guanylyltransferase family.
CC {ECO:0000256|ARBA:ARBA00010113}.
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DR EMBL; FTOR01000007; SIT27061.1; -; Genomic_DNA.
DR RefSeq; WP_076380720.1; NZ_FTOR01000007.1.
DR AlphaFoldDB; A0A173MFU7; -.
DR STRING; 477680.SAMN05421788_107126; -.
DR KEGG; fln:FLA_2484; -.
DR OrthoDB; 4547336at2; -.
DR Proteomes; UP000186917; Unassembled WGS sequence.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR GO; GO:0008193; F:tRNA guanylyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0006400; P:tRNA modification; IEA:InterPro.
DR Gene3D; 3.30.70.3000; -; 1.
DR InterPro; IPR025845; Thg1_C_dom.
DR InterPro; IPR024956; tRNAHis_GuaTrfase_cat.
DR InterPro; IPR007537; tRNAHis_GuaTrfase_Thg1.
DR InterPro; IPR038469; tRNAHis_GuaTrfase_Thg1_sf.
DR PANTHER; PTHR12729:SF6; TRNA(HIS) GUANYLYLTRANSFERASE-RELATED; 1.
DR PANTHER; PTHR12729; UNCHARACTERIZED; 1.
DR Pfam; PF04446; Thg1; 1.
DR Pfam; PF14413; Thg1C; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695,
KW ECO:0000313|EMBL:SIT27061.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000186917};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:SIT27061.1};
KW tRNA processing {ECO:0000256|ARBA:ARBA00022694}.
FT DOMAIN 9..126
FT /note="tRNAHis guanylyltransferase catalytic"
FT /evidence="ECO:0000259|Pfam:PF04446"
FT DOMAIN 135..217
FT /note="Thg1 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF14413"
SQ SEQUENCE 258 AA; 30416 MW; C4D94B009D25DC54 CRC64;
MKFDDLDYKM RVYETSQDRC VLPDMYLVAR IDGRSFTKLT KEVHQFEAPF DEKFRDLMVE
TVKHLMNCGF NIIYGYTESD EISLLFHPME NTFGRKTRKY ISILAGEASA KFSSLLGSVG
AFDCRLSELP NKKLVEDYFR WRNEDAHRNA LNAHCYWRLR GDRFSANEAT SKIEGMSTGA
KNELLFQYGV NFNNIPNWQK RGIGFYWKDV KKEGFNPKTN EHVWADKRIL YTDFDLPMRE
EYNTFINELV DKYDTVIV
//
