ID A0A173MHQ5_9BACT Unreviewed; 576 AA.
AC A0A173MHQ5;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
GN ORFNames=SAMN05421788_102220 {ECO:0000313|EMBL:SIS94200.1};
OS Filimonas lacunae.
OC Bacteria; Bacteroidota; Chitinophagia; Chitinophagales; Chitinophagaceae;
OC Filimonas.
OX NCBI_TaxID=477680 {ECO:0000313|EMBL:SIS94200.1, ECO:0000313|Proteomes:UP000186917};
RN [1] {ECO:0000313|Proteomes:UP000186917}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 21054 {ECO:0000313|Proteomes:UP000186917};
RA Varghese N., Submissions S.;
RL Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00034618};
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DR EMBL; FTOR01000002; SIS94200.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A173MHQ5; -.
DR STRING; 477680.SAMN05421788_102220; -.
DR KEGG; fln:FLA_3177; -.
DR Proteomes; UP000186917; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR PANTHER; PTHR11070:SF2; ATP-DEPENDENT DNA HELICASE SRS2; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR Pfam; PF00580; UvrD-helicase; 1.
DR Pfam; PF13361; UvrD_C; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000186917}.
FT DOMAIN 8..274
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT BINDING 29..36
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ SEQUENCE 576 AA; 65193 MW; 7FB2BD9CCAEC6E69 CRC64;
MVRFTYFRAM LTQEQEAIVN STGNIKINAV AGSGKTTTLL AYAAARPQQK ILYLAFNKAV
KLEAEKKFSA KRQHHVKVDT AHSLAFSRIV AGSKYTIKTE GYKIPEIVEI LQLNNYTGKH
TEYILATHIS ALIASFCNSN KLKVQEVNYE DTVTDAEALE FVNRHKEAIL YQARLFLDKM
NKAEIGITHD FYLKKLQLTK PQLPYDVILF DEGQDASEAM LDIFLSQKAI KVIVGDSHQQ
IYGWRNAVNS LEKVAYPTFH LSTSFRFNQE IAELATEVIG WKKRFQKNTT ITVKGAGKPP
EKVKTRAVVA RTNAGLLVKA IELLIEKKEI SSVYFEGRIE NYTYASDGAS IYDVLNLYTG
EKGRIRDPLI ASMANLDELE DYIDNTGDAQ LRMLVEVVKE YGKKIAGYIK KLKEDHLEHN
DKEKADMIFS TVHRCKGMEY DEVTLAGDFI TEDKIKSILA RQDDANIPKL AEEVNLLYVA
VTRTRGKINI PEELLSEEDD ATPVAKPKTT VQYAAKSRTY QASRNTNSGQ KPWKNNEDIR
LLRLFADGKP VIELAKFFGR TPVDVIRRIK ELNGKN
//
